Synthesis of 3,4-dihydro-1,8-naphthyridin-2(1H)-ones via microwave-activated inverse electron-demand Diels–Alder reactions
2014 ◽
Vol 10
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pp. 282-286
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Keyword(s):
Substituted 3,4-dihydro-1,8-naphthyridin-2(1H)-ones have been synthesized with the inverse electron-demand Diels–Alder reaction from 1,2,4-triazines bearing an acylamino group with a terminal alkyne side chain. Alkynes were first subjected to the Sonogashira cross-coupling reaction with aryl halides, the product of which then underwent an intramolecular inverse electron-demand Diels–Alder reaction to yield 5-aryl-3,4-dihydro-1,8-naphthyridin-2(1H)-ones by an efficient synthetic route.
2020 ◽
Vol 85
(5)
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pp. 3407-3416
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1993 ◽
Vol 58
(22)
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pp. 5889-5891
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Keyword(s):
Keyword(s):
1998 ◽
Vol 37
(17)
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pp. 2404-2406
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Keyword(s):
2002 ◽
Vol 113
(1)
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pp. 133-137
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Keyword(s):