ELECTROCHEMICAL ACETYLCHOLINESTERASE SENSORS BASED ON CARBON NANOMAERIALS FOR THE DETERMINATION OF DRUGS AND INSECTICIDES

2021 ◽  
Vol 1 (19) ◽  
pp. 231-232
Author(s):  
R.V. Shamagsumova
Keyword(s):  
Blood Serum ◽  
Carbon Nanomaterials ◽  
Enzyme Inhibitors ◽  
Single Component ◽  
Electrochemical Biosensors ◽  
Reversible Inhibitors

Operational and analytical characteristics of electrochemical biosensors based on acetylcholinesterase have been considered for the determination of enzyme inhibitors. As was shown, application of the mixtures of carbon nanomaterials increases sensitivity of determination over that of single component coatings. Biosensors were tested on determination of reversible inhibitors in urea and blood serum.

Polarographic study of hydrolysis of [8-lysine]vasopressin and its derivatives with blood serum of pregnant women

1980 ◽  
Vol 45 (4) ◽  
pp. 1099-1108 ◽  
Author(s):  
Mikuláš Chavko ◽  
Michal Bartík ◽  
Evžen Kasafírek
Keyword(s):  
Blood Serum ◽  
Pregnant Women ◽  
Degree Of Hydrolysis ◽  
Polarographic Study ◽  
Ph Optimum ◽  
Lysine Vasopressin ◽  
Rate Of Hydrolysis ◽  
Hydrolysis Of ◽  
Vasopressin Analogues

A polarographic study of the hydrolysis of [8-lysine]vasopressin and some hormonogens of the vasopressin series with the blood serum of women in the last week of pregnancy was studied. The dependence of hydrolysis on pH (pH optimum: 7.4-7.50, substrate concentration (Km 1.2 . 10-5M), pH stability and thermal stability were determined. The rate of hydrolysis of individual vasopressin analogues decreases in the order: [8-lysine]vasopressin > Nα-glycyl-prolyl[8-lysine]-vasopressin > Nα-leucyl-[8-lysine]vasopressin > Nα-alanyl-[8-lysine]vasopressin > Nα-phenyl alanyl-[8-lysine]vasopressin > Nα-diglycyl-[8-lysine]vasopressin > Nα-prolyl-[8-lysine]vasopressin > Nα-triglycyl-[8-lysine]vasopressin > Nα-sarcosyl-glycyl-[8-lysine]vasopressin. The degree of hydrolysis gradually increases to a multiple with the length of the pregnancy in consequence of the presence of oxytocine. However, vasopressin is also hydrolysed to a small extent with the enzymes from the blood sera of non-pregnant women. Under similar analytical conditions oxytocin was not hydrolysed with the sera of non-pregnant women and therefore oxytocin is a more suitable substrate than vasopressin for polarographic determination of serum oxytocinase.

scholarly journals THE DETERMINATION OF POTASSIUM IN BLOOD SERUM

1930 ◽  
Vol 87 (1) ◽  
pp. 27-32
Author(s):  
F.H.L. Taylor
Keyword(s):  
Blood Serum

Applications of antibiofouling PEG-coating in electrochemical biosensors for determination of glucose in whole blood

2013 ◽  
Vol 89 ◽  
pp. 549-554 ◽  
Author(s):  
Chong Sun ◽  
Jingjing Miao ◽  
Jie Yan ◽  
Kai Yang ◽  
Chun Mao ◽  
...  
Keyword(s):  
Whole Blood ◽  
Electrochemical Biosensors ◽  
Peg Coating

Determination of urea in 10-?l blood serum samples with a urease reactor / ion-selective electrode cell

1983 ◽  
Vol 81 (1-2) ◽  
pp. 135-147 ◽  
Author(s):  
U. Thanei-Wyss ◽  
W. E. Morf ◽  
P. Lienemann ◽  
Z. Stefanac ◽  
I. Mostert ◽  
...  
Keyword(s):  
Blood Serum ◽  
Ion Selective Electrode ◽  
Selective Electrode ◽  
Serum Samples ◽  
Electrode Cell
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