THE CAPACITY OF PHYSICAL THERAPY FOR REPEATED IMPLANTATION FAILURES IN IVF PROGRAMS: A LITERATURE REVIEW

Relevance: Studies of the etiology and pathogenesis of implantation failures, both repeated and primary, as well as the possibilities of therapy today carry many contraversions. However, in recent years, numerous studies have demonstrated the high effectiveness of various physiotherapy methods in improving reproductive outcomes, including therapy and overcoming repeated implantation failures in in-vitro fertilization programs. The purpose of the study was to study the capacity of physical therapy for repeated implantation failures in in-vitro fertilization programs. Materials and Methods: The capacity of physical therapy for repeated implantation failures in in-vitro fertilization programs were studied through the search and analysis of the scientific sources for 1995-2021, available in the Scopus and Pubmed databases, using the keywords “in-vitro fertilization,” “repeated implantation failure,” “assisted reproductive technology,” and «physiotherapy.» Results: Electrical impulse therapy has established itself as the most studied method in the treatment of disorders of endometrial receptivity with proven efficacy. Physical methods of exposure can improve reproductive outcomes through a beneficial effect on the angiogenesis and architectonics of the endometrium, improving its receptivity, and normalizing physiology. Further detailed study of the etiology, pathogenetic mechanisms, as well as the effectiveness of overcoming repeated implantation failures by various methods is needed to develop treatment protocols.

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Recent advances in in vitro fertilization

F1000Research ◽

10.12688/f1000research.11701.1 ◽

2017 ◽

Vol 6 ◽

pp. 1616 ◽

Cited By ~ 12

Author(s):

Robert Casper ◽

Jigal Haas ◽

Tzu-Bou Hsieh ◽

Rawad Bassil ◽

Chaula Mehta

Keyword(s):

In Vitro Fertilization ◽

Older Women ◽

Assisted Reproductive Technology ◽

Genetic Screening ◽

Oocyte Quality ◽

Reproductive Technology ◽

Endometrial Receptivity ◽

Vitro Fertilization ◽

New Methods

The field of assisted reproductive technology is rapidly progressing with many new advances in the last decade. The present review discusses methods to improve oocyte quality in older women and new stimulation protocols that may improve the number of mature oocytes retrieved during an in vitro fertilization cycle. We will discuss the present use of pre-implantation genetic screening (PGS) and finally focus on some new methods to determine endometrial receptivity. The focus of this review is to point out areas of technology that may be controversial or are new enough to require proper controlled studies for validation.

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Effect of luteal phase support gonadotropin-releasing hormone agonist on the endometrial receptivity and outcomes of in vitro fertilization programs

GYNECOLOGY ◽

10.26442/2079-5696_18.3.48-53 ◽

2016 ◽

Vol 18 (3) ◽

Cited By ~ 1

Author(s):

E.М. Savelyeva ◽

S.G. Perminova ◽

T.A. Demura ◽

D.A. Strelchenko

Keyword(s):

In Vitro Fertilization ◽

Luteal Phase ◽

Endometrial Receptivity ◽

Gonadotropin Releasing Hormone ◽

Vitro Fertilization ◽

Releasing Hormone ◽

Luteal Phase Support ◽

Gonadotropin Releasing Hormone Agonist

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Effects of Hydrosalpinx on Endometrial Implantation Failures: Evaluating Salpingectomy in Women Undergoing in vitro fertilization

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics ◽

10.1055/s-0040-1722155 ◽

2021 ◽

Author(s):

Antonio Palagiano ◽

Mauro Cozzolino ◽

Filippo Maria Ubaldi ◽

Chiara Palagiano ◽

Maria Elisabetta Coccia

Keyword(s):

In Vitro Fertilization ◽

Oocyte Retrieval ◽

Ovarian Response ◽

Antral Follicle ◽

Antral Follicle Count ◽

Endometrial Receptivity ◽

Vitro Fertilization ◽

Ovid Medline ◽

Ultrasonographic Guidance

AbstractHydrosalpinx is a disease characterized by the obstruction of the salpinx, with progressive accumulation in the shape of a fluid-filled sac at the distal part of the tuba uterina, and closed to the ovary. Women with hydrosalpinges have lower implantation and pregnancy rates due to a combination of mechanical and chemical factors thought to disrupt the endometrial environment. Evidence suggests that the presence of hydrosalpinx reduces the rate of pregnancy with assisted reproductive technology. The main aim of the present is review to make an overview of the possible effects of hydrosalpinx on in vitro fertilization (IVF). We conducted a literature search on the PubMed, Ovid MEDLINE, and Google Scholar data bases regarding hydrosalpinx and IVF outcomes. Hydrosalpinx probably has a direct toxic effect on sperm motility and on the embryos. In addition, the increasing liquid inside the salpinges could alter the mechanisms of endometrial receptivity. The window of endometrial receptivity is essential in the implantation of blastocysts, and it triggers multiple reactions arising from the endometrium as well as the blastocysts. Hydrosalpinx could influence the expression of homeobox A10 (HOXA10) gene, which plays an essential role in directing embryonic development and implantation. Salpingectomy restores the endometrial expression of HOXA10; therefore, it may be one mechanism by which tubal removal could result in improved implantation rates in IVF. In addition, salpingectomy does not affect the ovarian response, nor reduces the antral follicle count. Further studies are needed to establish the therapeutic value of fluid aspiration under ultrasonographic guidance, during or after oocyte retrieval, in terms of pregnancy rate and ongoing pregnancy.

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