According to Maxwell equations and constitutive relations in chiral medium, the dispersion characteristic of the symmetric slab waveguide with chiral negative refractive medium is studied. The dispersion equations expressed in the normalized parameter are deduced in the slab waveguide. The numerical results show that the chiral parameter has great influence on the dispersion characteristic of slab waveguide. When the relative chiral parameter is about 0.0477, the zero order mode of left-handed polarized wave disappears. While it is greater than 1, the core becomes chiral negative refractive medium and the zero order mode disappears. In addition, compared with the general chiral waveguide, the tendency of dispersion curves in slab waveguide with chiral negative refractive medium is also analyzed.