Coding metasurfaces have attracted tremendous interests due to unique capabilities of manipulating electromagnetic wave. However, archiving transmissive coding metasurface is still challenging. Here we propose a transmissive anisotropic coding metasurface that enables the independent control of two orthogonal polarizations. The polarization beam splitter and the OAM generator have been studied as typical applications of anisotropic 2-bit coding metasurface. The simulated far field patterns illustrate that the x and y polarized electromagnetic waves are deflected into two different directions, respectively. The anisotropic coding metasurface has been experimentally verified to realize an orbital angular momentum (OAM) beam with l = 2 of right-handed polarized wave, resulting from both contributions from linear-to-circular polarization conversion and the phase profile modulation. This work is beneficial to enrich the polarization manipulation field and develop transmissive coding metasurfaces.