A study of using manganese chloride (MnCl2) solution as an alternative of contrast medium for iodine in computed tomography (CT) imaging

Iodine solution is the only contrast medium currently used in the computed tomography scan (CT scan) examination. In the present study manganese chloride (MnCl2) solution has been chosen as alternative contrast medium in computed tomography scanning (CT scan). It was found that using MnCl2 solution as an alternative contrast medium in rabbits which enhanced the CT scan imaging in the resolution and increasing the Hounsfield unit (HU) values of heart and kidney organs in comparison with the iodine compound at the same doses. It was chosen the heart and kidney of rabbits to study the effect of using the iodine and MnCl2 solution as alternative contrast medium in CT scan imaging, the following results: the native has 45 HU for heart and 50.1 for kidney organ. While the results of using iodine solution at dose of 3 ml has 83 HU for heart and 164 HU for kidney organ. In the MnCl2 solution which used as alternative of contrast medium has 83 HU for heart and 70.3 HU for kidney at 2.5 ml of 0.5 molar of solution. From these results the resolution of CT scan image has well and clears when using the alternative contrast medium (MnCl2). We can concluded that the alternative contrast medium of MnCl2 solution has good HU values of both heart and kidney comparison with iodine solution.

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Spontaneous Regression of a Mandibular Plasmacytoma in a Juvenile Dog: A Case Report

Journal of the American Animal Hospital Association ◽

10.5326/jaaha-ms-6932 ◽

2020 ◽

Vol 56 (3) ◽

Author(s):

Erika Villedieu ◽

Samuel Beck ◽

Laurent Findji

Keyword(s):

Computed Tomography ◽

Spontaneous Regression ◽

Round Cell ◽

Computed Tomography Scan ◽

Computed Tomography Scanning ◽

Cell Neoplasm ◽

Poorly Differentiated ◽

The Right ◽

Tomography Scan ◽

Tomography Scanning

ABSTRACT A 4 mo old female Finnish lapphund presented for further investigation of a swelling of the right rostral mandible. A computed tomography scan showed the swelling to be an expansile and osteolytic mandibular lesion. Histopathology revealed a poorly differentiated, moderately well-demarcated, unencapsulated, highly infiltrative round cell neoplasm, and immunohistochemistry was supportive of a plasmacytoma. Performance of a rostral partial mandibulectomy was initially discussed with the owners, but the lesion improved spontaneously both clinically and on repeated computed tomography scanning before surgery could be performed. It subsequently almost completely resolved 6 mo after diagnosis. Hypotheses for spontaneous regression of the lesion are discussed and the human literature is briefly reviewed.

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Progressive Dyspnea Associated with a Crazy-Paving Appearance on a Chest Computed Tomography Scan

Canadian Respiratory Journal ◽

10.1155/2006/203830 ◽

2006 ◽

Vol 13 (5) ◽

pp. 269-271 ◽

Cited By ~ 4

Author(s):

Nimrod Maimon ◽

Narinder Paul ◽

Gregory P Downey

Keyword(s):

Computed Tomography ◽

Pulmonary Alveolar Proteinosis ◽

Present Report ◽

Computed Tomography Scan ◽

Chest Computed Tomography ◽

Progressive Dyspnea ◽

Computed Tomography Scanning ◽

Alveolar Proteinosis ◽

Tomography Scan ◽

Tomography Scanning

A ‘crazy-paving’ appearance of the lungs on computed tomography scanning of the chest was first described nearly 20 years ago in patients with pulmonary alveolar proteinosis, and was thought to be characteristic of this condition. However, this pattern has subsequently been reported in a variety of pulmonary diseases and is now considered to be nonspecific. The present report describes a case of a 74-year-old man in whom congestive heart failure presented with a crazy-paving appearance of the lungs on a chest computed tomography scan. This uncommon association illustrates the importance of the correlation of clinical and radiographic information.

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Solitary Lesions on Bone Scintigraphy in Patients with Breast Cancer King Abdulaziz University Medical Centre Experience

Journal of King Abdulaziz University-Medical Sciences ◽

10.4197/med.22-1.2 ◽

2015 ◽

Vol 22 (1) ◽

pp. 9-15

Author(s):

Nadia A. Batawil

Keyword(s):

Breast Cancer ◽

Computed Tomography ◽

Bone Scintigraphy ◽

Medical Centre ◽

Bone Lesions ◽

Computed Tomography Scan ◽

Computed Tomography Scanning ◽

King Abdulaziz University ◽

Tomography Scan ◽

Tomography Scanning

The discrepancy between bone scintigraphy and computed tomography scanning for solitary bony lesion in patients who have breast cancer is challenging to the referral physician. The purpose of this study was to evaluate the risk of malignancy in solitary lesions on bone scintigraphy in patients who had breast cancer at King Abdulaziz University Medical Centre, and to compare the results between bone scintigraphy and computed tomography scanning. There were 89 patients who had a solitary bone lesion noted on bone scintigraphy and computed tomography performed within 3 months of bone scintigraphy. The solitary bone lesions were benign in 56 (63%) patients and malignant in 33 patients (37%). There were 15 (17%) malignant lesions in bone scan that had initial computed tomography findings that were negative or equivocal for bone metastasis, but all these lesions had destructive changes on follow-up computed tomography scan. In summary, at this medical center the frequency of malignancy is high (37%) in solitary bone lesions in patients who have breast cancer, regardless of appearance of the lesion on an initial computed tomography scan. Prospective study with a larger group of patients is recommended.

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Computed Tomography Scan and ICD Interaction

Case Reports in Medicine ◽

10.1155/2009/189429 ◽

2009 ◽

Vol 2009 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

Jose M. Porres ◽

Jose L. Cerezuela ◽

Oscar Luque ◽

Pilar Marco

Keyword(s):

Computed Tomography ◽

Safe Procedure ◽

Computed Tomography Scan ◽

Thoracic Computed Tomography ◽

Computed Tomography Scanning ◽

High Doses ◽

Tomography Scan ◽

Tomography Scanning

Although it has been considered a safe procedure, computed tomography scanning uses high doses of radiation and can cause malfunctioning in those patients with ICD when the radiation is directly incident on the device. We present a case of ventricular oversensing during a thoracic computed tomography.

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Clinical Judgment Is Not Reliable for Reducing Whole-body Computed Tomography Scanning after Isolated High-energy Blunt Trauma

Anesthesiology ◽

10.1097/aln.0000000000001617 ◽

2017 ◽

Vol 126 (6) ◽

pp. 1116-1124 ◽

Cited By ~ 4

Author(s):

Thomas Mistral ◽

Vivien Brenckmann ◽

Laurence Sanders ◽

Jean-Luc Bosson ◽

Gilbert Ferretti ◽

...

Keyword(s):

Computed Tomography ◽

Clinical Judgment ◽

High Energy ◽

Whole Body ◽

Computed Tomography Scan ◽

Whole Body Computed Tomography ◽

Computed Tomography Scanning ◽

Significant Injury ◽

Tomography Scan ◽

Tomography Scanning

Abstract Background The purpose of this study was to test the diagnostic performance of clinical judgment for the prediction of a significant injury with whole-body computed tomography scanning after high-energy trauma. Methods The authors conducted an observational prospective study in a single level-I trauma center. Adult patients were included if they had an isolated high-energy injury. Senior trauma leaders were asked to make a clinical judgment regarding the likelihood of a significant injury before performance of a whole-body computed tomography scan. Clinical judgments were recorded using a probability diagnosis scale. The primary endpoint was the diagnosis of a serious-to-critical lesion on the whole-body computed tomography scan. Diagnostic performance was assessed using receiver operating characteristic analysis. Results Of the 354 included patients, 127 patients (36%) had at least one injury classified as abbreviated injury score greater than or equal to 3. The area under the receiver operating characteristic curve of the clinical judgment to predict a serious-to-critical lesion was 0.70 (95% CI, 0.64 to 0.75%). The sensitivity of the clinical judgment was 82% (95% CI, 74 to 88%), and the specificity was 49% (95% CI, 42 to 55%). No patient with a strict negative clinical examination had a severe lesion (n = 19 patients). The sensitivity of the clinical examination was 100% (95% CI, 97 to 100%) and its specificity was 8% (95% CI, 5 to 13%). Conclusions Clinical judgment alone is not sufficient to reduce whole-body computed tomography scan use. In patients with a strictly normal physical examination, whole-body computed tomography scanning might be avoided, but this result deserves additional study in larger and more diverse populations of trauma patients.

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Comparative study of orbital involvement in invasive and non-invasive fungal sinusitis

The Journal of Laryngology & Otology ◽

10.1017/s0022215111003185 ◽

2011 ◽

Vol 126 (2) ◽

pp. 152-158 ◽

Cited By ~ 7

Author(s):

R Chandrasekharan ◽

M Thomas ◽

V Rupa

Keyword(s):

Computed Tomography ◽

Optic Atrophy ◽

Fungal Sinusitis ◽

Orbital Involvement ◽

Non Invasive ◽

Invasive Fungal Sinusitis ◽

Computed Tomography Scanning ◽

The Difference ◽

Tomography Scan ◽

Tomography Scanning

AbstractObjective:To investigate differences in orbital involvement in patients with invasive versus non-invasive fungal sinusitis.Method:One hundred consecutive cases of fungal sinusitis were assessed clinically and by computed tomography scan to evaluate orbital involvement.Results:Clinical orbital involvement was more common in invasive (73.5 per cent) than non-invasive (12.1 per cent) fungal sinusitis (p = 0.000). Computed tomography scanning showed similar orbital involvement in both groups, except for erosion of the floor of the orbit, which was more common in patients with invasive fungal sinusitis (p = 0.01). Extra-ocular muscle enlargement (44.4 vs 4 per cent, p = 0.01) and optic atrophy (44.4 vs 0 per cent, p = 0.003) were more common in chronic than acute invasive fungal sinusitis. Four patients (16 per cent) with acute invasive fungal sinusitis had no evidence of orbital involvement on scanning, despite clinical evidence of optic atrophy.Conclusion:Orbital involvement is more common in invasive than non-invasive fungal sinusitis. The difference is more evident clinically than on computed tomography scanning. Patients with acute invasive fungal sinusitis may have limited evidence of orbital involvement on scanning, despite extensive clinical disease.

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Hubungan Antara Kadar DNA Plasma Virus Epstein Barr Dengan Stadium Klinis Karsinoma Nasofaring WHO Tipe 3

Oto Rhino Laryngologica Indonesiana ◽

10.32637/orli.v48i2.277 ◽

2019 ◽

Vol 48 (2) ◽

pp. 165

Author(s):

Putranti Dyahayu Roziaty ◽

Soehartono Soehartono ◽

Hendradi Surjotomo

Keyword(s):

Computed Tomography ◽

Ct Scan ◽

Epstein Barr Virus ◽

Tumor Type ◽

Computed Tomography Scan ◽

Cross Sectional ◽

Barr Virus ◽

Ebv Dna ◽

Epstein Barr ◽

Tomography Scan

Latar Belakang: Karsinoma nasofaring (KNF) merupakan keganasan yang tersering ditemukan, dan berdampak pada penurunan kualitas hidup serta memiliki mortalitas tinggi. Penanganan KNF selama ini terkendala oleh waktu tunggu yang cukup lama dalam menentukan staging KNF terutama untuk antrian pemeriksaan computed tomography scan (CT scan) dan Ultrasonography (USG). Pemeriksaan kadar DNA EBV (Deoxyribonucleic acid Epstein-Barr Virus) pada pasien yang relatif lebih mudah dan terjangkau dapat digunakan untuk memprediksi stadium dan prognosis KNF. Dengan mengetahui prognosis KNF lebih dini, maka diharapkan penanganan terhadap KNF dapat segera dilakukan. Tujuan: Mengetahui apakah kadar DNA EBV dapat dipakai untuk memprediksi stadium dan prognosis KNF dengan cara mencari hubungan antara kadar DNA EBV dengan stadium KNF. Metode: Penelitian cross sectional melibatkan 15 subjek penelitian yang terdiagnosis KNF WHO tipe 3 kemudian dilakukan staging dengan CT scan, USG abdomen, dan foto toraks, serta diambil sampel darah untuk diukur kadar DNA EBV. Hasil: Seluruh subjek penelitian mengalami peningkatan kadar DNA EBV sesuai dengan peningkatan stadium KNF. Peningkatan stadium KNF berhubungan signifikan dengan peningkatan kadar DNA EBV (p=0,001). Ukuran tumor (T) berhubungan signifikan dengan kadar DNA EBV (p=0,023), ukuran nodul (N) berhubungan signifikan dengan kadar DNA EBV (p=0,005), ada tidaknya metastasis tidak berhubungan signifikan dengan kadar DNA EBV (p=0,398). Nilai cut off kadar DNA EBV sebesar 952 kopi/ml. Kesimpulan: Terdapat hubungan yang signifikan antara kadar DNA EBV dengan stadium klinis, dengan demikian kadar DNA EBV dapat dipertimbangkan untuk digunakan sebagai prediktor stadium dan prognosis KNF. Background: Nasopharyngeal carcinoma (NPC) is the predominant tumor type arising in the nasopharynx, with a high mortality and affecting quality of life. NPC treatment management is hindered by long queues of Computed Tomography Scan (CT scan) and Ultrasonography (USG) examinations to ascertain the NPC staging. The examination of Epstein-Barr Virus (EBV) DNA level is relatively simpler and inexpensive to predict the NPC staging and prognosis, thus, it can speed up NPC treatment. Objective: To determine whether EBV DNA level can be used to predict the NPC stage and prognosis by finding a correlation between EBV DNA level and NPC stage. Method: This was a cross-sectional study involving 15 respondents who were diagnosed as WHO type 3 NPC, and examined by CT scan, abdominal ultrasound, chest X-ray, and blood test for measuring the levels of EBV DNA to determine the stage. Results: All respondents had elevated levels of EBV DNA in accordance with NPC stage elevation. Increased NPC stages were significantly correlated with elevated levels of EBV DNA (p=0.001). The size of tumor (T) was significantly correlated with EBV DNA (p=0.023), the size of nodule (N) was significantly correlated with EBV DNA (p=0.005). The presence or absence of metastasis did not significantly correlate with EBV DNA (p=0.398). The EBV DNA cut off value was 952 copies/ml. Conclusions: There was a significant correlation between EBV DNA levels and clinical stages, hence EBV DNA can be considered to be used as NPC staging and prognosis predictor.

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Anatomic Variations of the Nose in Chronic Rhinosinusitis: Correlation between Nasal Endoscopic and Computerized Tomography Scan Findings and a Review of Literature

Clinical Rhinology An International Journal ◽

10.5005/jp-journals-10013-1255 ◽

2016 ◽

Vol 9 (1) ◽

pp. 13-17

Author(s):

Priyanko Chakraborty ◽

Rajiv K Jain ◽

Purnima Joshi ◽

Rakhi Kumari ◽

Sidharth Pradhan

Keyword(s):

Computed Tomography ◽

Ct Scan ◽

Chronic Rhinosinusitis ◽

Sinus Surgery ◽

Anatomic Variations ◽

Review Of Literature ◽

Computed Tomography Scan ◽

Diagnostic Endoscopy ◽

The Mean ◽

Tomography Scan

ABSTRACT Background Chronic rhinosinusitis (CRS) refers to a group of disorders characterized by inflammation of the mucosa of the paranasal sinuses. Nasal endoscopy and computed tomography (CT) scans are successfully used as diagnostic modalities of nose and paranasal sinus diseases. There have been many studies regarding the anatomic variations leading to pathogenesis of paranasal sinus diseases. Considerable progress has been made in the medical and surgical control of these conditions; however, a large number of questions relating to the diagnosis, evaluation, and treatment of the diseases remain unanswered. Materials and methods The study included 82 clinically diagnosed cases of CRS who underwent CT scan and were advised to undergo diagnostic endoscopy. The anatomical findings of the nose were compared to see correlation between nasal endoscopy and CT scan. Results The mean age (±standard error of the mean) of presentation was 34.11 (±1.42) years, while most patients were from the age group of 18 to 30 years. Males were predominating the study group with 62.2%, while 37.8% were females. The most common anatomic variation was deviated nasal septum with 92.68% CT reported patients. This was followed by inferior turbinate hypertrophy, septal spur, concha bullosa, and agger nasi cells. Conclusion Computed tomography scan is considered the gold standard for sinonasal imaging. Diagnostic endoscopy and CT scan are a must prior to any functional endoscopic sinus surgery. They help in assessing the extent of sinus disease and to know the variations and vital relations of the paranasal sinuses. Computed tomography scan assists the surgeon as a “road map” during endoscopic sinus surgery. How to cite this article Chakraborty P, Jain RK, Joshi P, Kumari R, Pradhan S. Anatomic Variations of the Nose in Chronic Rhinosinusitis: Correlation between Nasal Endoscopic and Computerized Tomography Scan Findings and a Review of Literature. Clin Rhinol An Int J 2016;9(1):13-17.

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