Physiologic Patient Derived 3D Spheroids for Anti-neoplastic Drug Screening to Target Cancer Stem Cells

10.3791/59696 ◽  
2019 ◽  
Author(s):  
Michael E. Bregenzer ◽  
Ciara Davis ◽  
Eric N. Horst ◽  
Pooja Mehta ◽  
Caymen M. Novak ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Drug Screening ◽  
3D Spheroids ◽  
Target Cancer

scholarly journals 11R-P53 and GM-CSF Expressing Oncolytic Adenovirus Target Cancer Stem Cells with Enhanced Synergistic Activity

2017 ◽  
Vol 8 (2) ◽  
pp. 199-206 ◽  
Author(s):  
Sai-qun Lv ◽  
Zhen-long Ye ◽  
Pin-yi Liu ◽  
Yao Huang ◽  
Lin-fang Li ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Oncolytic Adenovirus ◽  
Synergistic Activity ◽  
Gm Csf ◽  
Target Cancer

Abstract C21: Generation of Wnt- and mitogenic receptor binding bispecific antibodies to target cancer stem cells

2015 ◽  
Author(s):  
Berina Eppink ◽  
Rob Roovers ◽  
Bram Herpers ◽  
Wim de Lau ◽  
Carina Clements ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Receptor Binding ◽  
Bispecific Antibodies ◽  
Target Cancer

scholarly journals Small-Molecule Ferroptotic Agents with Potential to Selectively Target Cancer Stem Cells

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
William R. Taylor ◽  
Sara R. Fedorka ◽  
Ibtissam Gad ◽  
Ronit Shah ◽  
Hanan D. Alqahtani ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Small Molecule ◽  
Target Cancer

scholarly journals Therapeutic Approaches to Target Cancer Stem Cells

Cancers ◽  
2011 ◽  
Vol 3 (3) ◽  
pp. 3331-3352 ◽  
Author(s):  
Arlhee Diaz ◽  
Kalet Leon
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Therapeutic Approaches ◽  
Target Cancer

scholarly journals Smac Mimetics in Combination with TRAIL Selectively Target Cancer Stem Cells in Nasopharyngeal Carcinoma

2013 ◽  
Vol 12 (9) ◽  
pp. 1728-1737 ◽  
Author(s):  
Man-si Wu ◽  
Guang-feng Wang ◽  
Zhi-qiang Zhao ◽  
Yi Liang ◽  
Heng-bang Wang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Nasopharyngeal Carcinoma ◽  
Cancer Stem Cells ◽  
Smac Mimetics ◽  
Target Cancer

scholarly journals Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells

Cell ◽  
2012 ◽  
Vol 149 (6) ◽  
pp. 1284-1297 ◽  
Author(s):  
Eleftherios Sachlos ◽  
Ruth M. Risueño ◽  
Sarah Laronde ◽  
Zoya Shapovalova ◽  
Jong-Hee Lee ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cancer Stem Cells ◽  
Receptor Antagonist ◽  
Dopamine Receptor ◽  
Dopamine Receptor Antagonist ◽  
Target Cancer

scholarly journals Aberrant lipid metabolism as an emerging therapeutic strategy to target cancer stem cells

Stem Cells ◽  
2019 ◽  
Vol 38 (1) ◽  
pp. 6-14 ◽  
Author(s):  
Malini Visweswaran ◽  
Frank Arfuso ◽  
Sudha Warrier ◽  
Arun Dharmarajan
Keyword(s):  
Stem Cells ◽  
Lipid Metabolism ◽  
Cancer Stem Cells ◽  
Therapeutic Strategy ◽  
Target Cancer
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