Herpes virus reactivation after initiation of interferon-free antiviral agents in HIV–HCV-coinfected subjects: a new immune restoration disease?

2016 ◽  
Vol 21 (8) ◽  
pp. 739-742 ◽  
Author(s):  
Raffaella Marocco ◽  
Miriam Lichtner ◽  
Tiziana Tieghi ◽  
Irene Pozzetto ◽  
Claudio M Mastroianni
2021 ◽  
Vol 14 (3) ◽  
pp. e239220
Author(s):  
Maria Alkozah ◽  
Rami Hallak ◽  
Imad Bou Akl ◽  
Aline El Zakhem

Human herpes virus-6 (HHV-6) infection is a common infection in the paediatric population and is increasingly reported in immunosuppressed adult patients. It has been reported as the causative agent of disease in few case reports in immunocompetent adults. We report herein an unusual case of HHV-6-associated viraemia, pneumonitis and meningitis in a patient who presented with dyspnoea, hypoxia, dry cough and headache. She was treated for atypical pneumonia with no improvement. Meningitis was suspected as headache kept worsening. HHV-6B was detected by PCR in the cerebrospinal fluid, and subsequently, in the bronchoalveolar lavage and serum samples. Studies were negative for the most common primary and secondary immunodeficiency syndromes, and serology could not be performed to differentiate virus reactivation from a primary infection. The patient was successfully treated with ganciclovir and had no residual sequelae.


2016 ◽  
Vol 09 (01) ◽  
pp. 25
Author(s):  
Khalid F Tabbara ◽  

Herpetic keratitis is a common cause of ocular morbidity and corneal blindness. The disease has a worldwide distribution. There are different types of Herpes virus with variable ocular and adnexal manifestations. Herpes virus stays dormant in the nerve ganglia following a primary infection. Topical antiviral agents include acyclovir and ganciclovir. Both agents may be used for the treatment and prophylaxis of herpetic keratitis. Antiviral prophylaxis is of crucial importance in the prevention of recurrent keratitis in patients with penetrating keratoplasty for herpes induced corneal scars. Recurrent herpetic keratitis in such patients frequently eventuate in the rejection of the graft. This article reviews topical ganciclovir 0.15% gel in the therapy and prophylaxis of herpetic keratitis.


2011 ◽  
Vol 29 (2) ◽  
pp. 83-90 ◽  
Author(s):  
Hazem Mohammad Saleh ◽  
Ahmed Samir Shaker ◽  
Ali Mohamed Saafan ◽  
Adel Khalil Ibrahim

Molecules ◽  
2015 ◽  
Vol 20 (6) ◽  
pp. 10689-10704 ◽  
Author(s):  
Juliana Mello ◽  
Nathália Botelho ◽  
Alessandra Souza ◽  
Riethe Oliveira ◽  
Monique Brito ◽  
...  

2009 ◽  
Vol 149 (2) ◽  
pp. 173-177 ◽  
Author(s):  
Lorenzo Calligaris ◽  
Gabriele Stocco ◽  
Sara De Iudicibus ◽  
Sara Marino ◽  
Giuliana Decorti ◽  
...  

Author(s):  
Raymond P. Stowe ◽  
Duane L. Pierson ◽  
Satish K. Mehta

Author(s):  
Raymond P. Stowe ◽  
Duane L. Pierson ◽  
Satish K. Mehta

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