Microvessel density predicts the radiosensitivity of metastatic head and neck squamous cell carcinoma in cervical lymph nodes

Author(s):  
Yoshinori Ito ◽  
Tomoyuki Kamijo ◽  
Tomoyuki Yokose ◽  
Mitsuhiko Kawashima ◽  
Takashi Ogino ◽  
...  

Head & Neck ◽  
2007 ◽  
Vol 29 (7) ◽  
pp. 621-631 ◽  
Author(s):  
Michael J. Veness ◽  
Sandro Porceddu ◽  
Carsten E. Palme ◽  
Gary J. Morgan


2010 ◽  
Vol 113 (10) ◽  
pp. 1827-1833 ◽  
Author(s):  
Michael J. Veness ◽  
Carsten E. Palme ◽  
Mark Smith ◽  
Burcu Cakir ◽  
Gary J. Morgan ◽  
...  












Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 407
Author(s):  
Hoshino Terada ◽  
Yuzo Shimode ◽  
Madoka Furukawa ◽  
Yuichiro Sato ◽  
Nobuhiro Hanai

Background and Objectives: There is evidence or consensus on the use of 18F-2-fluorodeoxyglucose-positron emission tomography with computed tomography (PET-CT) in evaluating the effects of treatment at 12 weeks after chemoradiotherapy for head and neck squamous cell carcinoma with cervical lymph node metastasis. However, the use of imaging to evaluate the effects of treatment within 12 weeks after chemoradiotherapy is controversial. The aim of this study was to evaluate the usefulness of ultrasonography in the diagnosis of lymph nodes metastasis after chemoradiotherapy according to the criteria of the “Evaluation of the effects of treatment on metastatic cervical lymph nodes using ultrasonography”, which evaluated lymph nodes metastasis based on size change and presence of degeneration. Materials and methods: This prospective study included 34 head and neck squamous cell carcinoma patients with cervical lymph nodes metastasis. Thirty-two patients who completed treatment were analyzed. Ultrasonography was performed at 4 and 8 weeks after chemoradiotherapy and we judged whether a favorable prognosis could be expected or whether additional treatments should be considered. Ultrasonography and PET-CT were performed at 12 weeks after chemoradiotherapy. Neck dissection was performed if residual disease was suspected based on the PET-CT findings. Results: The accuracy and negative predictive value of ultrasonography were 81.3% and 96.3%, respectively. According to the Ultrasonography findings, the size of lymph nodes metastasis after chemoradiotherapy was significantly smaller than those before chemoradiotherapy (p < 0.05). The fluid and blood flow of lymph nodes metastasis showed a significantly reduced at 12 weeks after chemoradiotherapy (p < 0.05, p < 0.05, respectively). The echo density significantly changed from low to high echoic density after chemoradiotherapy (p < 0.05). Conclusions: Ultrasonography was useful for evaluating cervical lymph nodes metastasis after chemoradiotherapy for head and neck squamous cell carcinoma.



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