scholarly journals Successful treatment of a patient with Philadelphia chromosome‑positive acute lymphoblastic leukemia complicated by bone marrow necrosis and acute renal insufficiency: A case report

2018 ◽  
Author(s):  
Jieyun Xia ◽  
Haiying Sun ◽  
Zhiling Yan ◽  
Feng Zhu ◽  
Kai Zhao ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Case Report ◽  
Acute Lymphoblastic Leukemia ◽  
Renal Insufficiency ◽  
Successful Treatment ◽  
Lymphoblastic Leukemia ◽  
Philadelphia Chromosome ◽  
Bone Marrow Necrosis ◽  
Acute Renal Insufficiency ◽  
Philadelphia Chromosome Positive

A Case of Bone Marrow Necrosis in B-Acute Lymphoblastic Leukemia with Philadelphia Chromosome at Presentation

2018 ◽  
Vol 8 (4) ◽  
pp. 171
Author(s):  
In Hwa Jeong ◽  
Gyu Dae An ◽  
Hyeon Ho Lim ◽  
Kwang Sook Woo ◽  
Kyeong Hee Kim ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Philadelphia Chromosome ◽  
Bone Marrow Necrosis

scholarly journals Bone marrow transplantation for patients with Philadelphia chromosome- positive acute lymphoblastic leukemia

Blood ◽  
1987 ◽  
Vol 70 (2) ◽  
pp. 587-588 ◽  
Author(s):  
SJ Forman ◽  
MR O'Donnell ◽  
AP Nademanee ◽  
DS Snyder ◽  
PJ Bierman ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Acute Lymphoblastic Leukemia ◽  
Bone Marrow Transplantation ◽  
Marrow Transplantation ◽  
Lymphoblastic Leukemia ◽  
Allogeneic Bone Marrow Transplantation ◽  
Philadelphia Chromosome ◽  
Allogeneic Bone ◽  
Marrow Ablation ◽  
Philadelphia Chromosome Positive

We report the treatment outcome of allogeneic bone marrow transplantation in ten patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Six patients are alive and well for 6 to 30 months (median 19 months) after transplantation. Four patients died with transplant related complications. In view of the poor prognosis associated with this disease, marrow ablation followed by allogeneic or syngeneic marrow grafting may be the preferred treatment modality if a suitable marrow donor is available.

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