scholarly journals Silencing activating transcription factor 2 promotes the anticancer activity of sorafenib in hepatocellular carcinoma cells

2018 ◽  
Author(s):  
Lifang Luo ◽  
Lijing Cai ◽  
Laibang Luo ◽  
Zhimou Tang ◽  
Xiaohui Meng
Keyword(s):  
Hepatocellular Carcinoma ◽  
Transcription Factor ◽  
Anticancer Activity ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells ◽  
Activating Transcription Factor

HBx induces the proliferation of hepatocellular carcinoma cells via AP1 over-expressed as a result of ER stress

2015 ◽  
Vol 466 (1) ◽  
pp. 115-121 ◽  
Author(s):  
Hyun Kook Cho ◽  
So Young Kim ◽  
Yi Yi Kyaw ◽  
Aye Aye Win ◽  
Seung-Hoi Koo ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Proliferation ◽  
Transcription Factor ◽  
Er Stress ◽  
Critical Role ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

HBx protein is encoded by HBV and plays a critical role in hepatocarcinogenesis. In the present study we show that HBx activates the expression of the CREBH transcription factor and interacts with the activated CREBH. CREBH activation by HBx may result in cell proliferation.

scholarly journals Vitamin C enhances anticancer activity in methotrexate-treated Hep3B hepatocellular carcinoma cells

2014 ◽  
Vol 32 (3) ◽  
pp. 1057-1063 ◽  
Author(s):  
GIOU-TENG YIANG ◽  
PEI-LUN CHOU ◽  
YU-TING HUNG ◽  
JEN-NI CHEN ◽  
WEI-JUNG CHANG ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Vitamin C ◽  
Anticancer Activity ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells
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