Spindle-cell ameloblastic carcinoma: A case report with immunohistochemical, ultrastructural, and comparative genomic hybridization analyses

2003 ◽  
Author(s):  
Shigeto Kawauchi ◽  
Yoshikazu Hayatsu ◽  
Mutsuo Takahashi ◽  
Tomoko Furuya ◽  
Atsunori Oga ◽  
...  
Keyword(s):  
Case Report ◽  
Comparative Genomic Hybridization ◽  
Spindle Cell ◽  
Comparative Genomic ◽  
Ameloblastic Carcinoma ◽  
Genomic Hybridization

scholarly journals Invasive melanoma in a 5-year-old Canadian patient: A case report

2019 ◽  
Vol 7 ◽  
pp. 2050313X1982963
Author(s):  
Joanna Yuen ◽  
Fatmah AlZahrani ◽  
Garnet Horne ◽  
Karen Naert ◽  
Timothy McCalmont ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Comparative Genomic Hybridization ◽  
Array Comparative Genomic Hybridization ◽  
Melanocytic Nevus ◽  
Chromosome 9 ◽  
Comparative Genomic ◽  
Genomic Hybridization ◽  
Mitotic Figures ◽  
Canadian Patient

Atypical Spitzoid lesions pose a distinct challenge in classification as they may comprise a mixture of both classic benign nevus and cutaneous melanoma characteristics. Immunostaining and molecular analysis, such as comparative genomic hybridization, can assist in narrowing the differential diagnosis. We present a case of a 5-year-old male with an atypical Spitzoid lesion on his back. Initial histopathology revealed a relatively symmetric lesion with mitotic figures and poor maturation of melanocytes with descent into the dermis. Immunohistochemistry demonstrated a loss of p16, and array comparative genomic hybridization revealed a loss of chromosome 9, supporting a diagnosis of invasive melanoma arising in conjunction with a remnant of a conventional melanocytic nevus. This case is the first in Canada to demonstrate the use of array comparative genomic hybridization for diagnosing melanoma in a young paediatric patient.

Proximal-type epithelioid sarcoma: case report and result of comparative genomic hybridization

2003 ◽  
Vol 31 (1) ◽  
pp. 67-71 ◽  
Author(s):  
Mi-Woo Lee ◽  
Kowan-Ja Jee ◽  
Jae-Yoon Ro ◽  
Deuk-Pyo Lee ◽  
Jee-Ho Choi ◽  
...  
Keyword(s):  
Case Report ◽  
Comparative Genomic Hybridization ◽  
Epithelioid Sarcoma ◽  
Comparative Genomic ◽  
Genomic Hybridization
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