scholarly journals Optimal time to surgery following neoadjuvant chemotherapy and its effect on the survival of patients with breast cancer

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
B. Pedamallu ◽  
Delilah Hassanally ◽  
Abdul Kasem ◽  
Charlotte Abson ◽  
Ibrahim Ahmed
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Optimal Time ◽  
Time To Surgery

scholarly journals Clinical Impact of Delaying Surgery in Patients Undergoing Neoadjuvant Chemotherapy on Breast Cancer Recurrence and Survival

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 70s-70s
Author(s):  
J. Lin ◽  
L. Anna
Keyword(s):  
Breast Cancer ◽  
Overall Survival ◽  
Neoadjuvant Chemotherapy ◽  
Cancer Recurrence ◽  
Disease Free Survival ◽  
Optimal Time ◽  
Study Cohort ◽  
Free Survival ◽  
Time To Surgery ◽  
Kaplan Meier

Background: For patients with breast cancer, the optimal time of surgery after completion of neoadjuvant chemotherapy (NAC) is unknown. Aim: We evaluated the association between time to surgery after NAC completion and disease free survival (DFS) and overall survival (OS). Methods: Women diagnosed with breast cancer stages I to III between 2013-2016 who received NAC at our institution were included. Patients were categorized into two groups according to time to surgery after completion of NAC ≤ 60 days, and > 60 days. Survival outcomes were estimated and compared according to time to surgery after NAC completion. Statistical analysis was done using the Kaplan-Meier estimate. Groups were then compared by log rank. Results: In total, 58 patients treated with NAC were included in the study. The median interval to surgery after completion of NAC was 29 days. Five-year DFS was 82% for patients with surgery < 60 days and 63% for patients with surgery > 60 days after NAC completion (log rank z=2.32, P = 0.02). A surgery date of > 60 days after NAC completion was associated with shorter DFS. Five-year OS was 89% for patients with surgery < 60 days and 90% for patients > 60 days after NAC completion (log rank z=0.14, P = 0.89). A surgery date of > 60 days after NAC completion was not associated with a poorer overall survival. Conclusion: Time to surgery after completion of NAC influenced recurrence outcomes but not overall survival in our study cohort. Our findings suggest that the timing of surgery after completion of NAC is crucial for recurrence, but not survival, for patients undergoing NAC.

Time to surgery following neoadjuvant chemotherapy for breast cancer impacts residual cancer burden, recurrence, and survival

2020 ◽  
Vol 122 (8) ◽  
pp. 1761-1769
Author(s):  
Thomas L. Sutton ◽  
Alexander Schlitt ◽  
Stuart K. Gardiner ◽  
Nathalie Johnson ◽  
Jennifer R. Garreau
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Residual Cancer ◽  
Cancer Burden ◽  
Residual Cancer Burden ◽  
Time To Surgery

scholarly journals Time to surgery in early breast cancer treated with neoadjuvant chemotherapy

2017 ◽  
Vol 28 ◽  
pp. v49-v50
Author(s):  
M. Cinausero ◽  
G. Galli ◽  
D. Basile ◽  
L. Gerratana ◽  
G. Fasola ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Early Breast Cancer ◽  
Time To Surgery

scholarly journals Time to surgery after neoadjuvant chemotherapy for early breast cancer

2017 ◽  
Vol 28 ◽  
pp. vi29
Author(s):  
M. Cinausero ◽  
G. Galli ◽  
D. Basile ◽  
L. Gerratana ◽  
G. Fasola ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Early Breast Cancer ◽  
Time To Surgery

Retrospective audit on time to surgery delays after completion of neoadjuvant chemotherapy in breast cancer patients.

2021 ◽  
Vol 47 (2) ◽  
pp. e39
Author(s):  
B Srinivas Pedamallu ◽  
Delilah Hassanally ◽  
Abdul Kasem ◽  
Charlotte Abson ◽  
Ibrahim Ahmed
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Time To Surgery ◽  
Retrospective Audit

Optimum Time to Surgery after Neoadjuvant Chemotherapy and Its Survival Impact in Breast Cancer Patients. A Retrospective Study.

2020 ◽  
Vol 46 (2) ◽  
pp. e62
Author(s):  
B Srinivas Pedamallu ◽  
Ibrahim Ahmed ◽  
Delilah Hassanally ◽  
Abdul Kasem ◽  
Charlotte Abson
Keyword(s):  
Breast Cancer ◽  
Retrospective Study ◽  
Neoadjuvant Chemotherapy ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Optimum Time ◽  
Time To Surgery

Impact of time to surgery after neoadjuvant chemotherapy in operable breast cancer patients

2017 ◽  
Vol 43 (4) ◽  
pp. 613-618 ◽  
Author(s):  
C. Omarini ◽  
G. Guaitoli ◽  
S. Noventa ◽  
A. Andreotti ◽  
A. Gambini ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Cancer Patients ◽  
Operable Breast Cancer ◽  
Breast Cancer Patients ◽  
Time To Surgery

scholarly journals Impact of time to surgery after neoadjuvant chemotherapy in patients with operable breast cancer

2015 ◽  
Vol 26 ◽  
pp. vi4
Author(s):  
F. Piacentini ◽  
M.E. Filieri ◽  
G. Grizzi ◽  
C. Omarini ◽  
M. Maur ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Operable Breast Cancer ◽  
Time To Surgery

scholarly journals Factors influencing the time to surgery after neoadjuvant chemotherapy in breast cancer patients

2020 ◽  
Vol 301 (4) ◽  
pp. 1055-1059
Author(s):  
Carolin Müller ◽  
Ingolf Juhasz-Böss ◽  
Gilda Schmidt ◽  
Peter Jungmann ◽  
Erich-Franz Solomayer ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Time To Surgery ◽  
Factors Influencing
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