As a compound modifying and flooding agent, the organic-inorganic crosslinked plugging system which is mixed by gel and silicide according our experimental study, formed integral crosslinked system at high temperature and varied in a broad range gelling time by regulate concentration of organic-inorganic crosslinked plugging system. It exhibits excellent thermostability, shear properties, plugging performance and washable characteristic. In this visual experiment, the organic-inorganic crosslinked plugging systems injection, waterflooding effect and sealing capacity on homogeneous reservoir and heterogeneous reservoir are all exhibited clearly. The results of experiment show that organic-inorganic crosslinked plugging system has a good injectivity and water plugging performance. Depth of injection has an important effect on water-flooding situation, further influencing the increasement of recovery factor. Before the injection of Organic-Inorganic Crosslinked Plugging System, we inject some viscosity reducer, such as foam solution which reducing the deep oil viscosity, keeping the high recovery efficiency and preventing the mistaken plugging.