US foreign policy during the Obama administration, especially in the second term, has focused to resolve its international crises in the Middle East and tried to resolve the Iranian nuclear issue. In the current article, different approaches are brought forth in the field of discerning deterrence mechanisms that are feasible against asymmetric hazards. In the following, the attempts has been made to answer the question of how deterrence can be utilized as a mechanism to face asymmetric threats, and what role can Iran's nuclear program play in deterring countries in power in this process?. Hence, from the analysis of the mentioned model, we will present the main and major assumptions of the current article under four headings: deterrent measures, coercive measures, anti-deployment measures and counter-offensive measures. The tensions between Iran and the West are not the product of Iran's nuclear program, but are based on the religious ideology of the Iranian government and Israel's presence in the region, although the role of some Arab countries, especially Saudi Arabia, should not be disregarded. The hypothesis under consideration is that US foreign policy in the Iranian nuclear case has been directed towards the interaction of national interests by following the rational, organizational and bureaucratic model of decision-making models. The result of the research is that think tanks are very determining in leading the US government to the White House foreign policy decision-maker towards Iran, so that diplomacy actors cannot escape it. And public opinion seeks to make Iran's nuclear energy dangerous and to prevent Iran from obtaining a nuclear weapon as a serious threat to humanity. Though, the Islamic Republic of Iran, with its power to obtain nuclear weapons, does not intend to build a nuclear bomb, nor does it intend to make the world insecure. The power of reaching to a nuclear weapon can play a key and major role for Iran as a deterrent, and Iran intends to use nuclear energy not to build a bomb but to make it peaceful.