Preparation of Macroporous Glass-Ceramic Composites Containing β-TCP

2006 ◽  
Vol 11-12 ◽  
pp. 223-226
Author(s):  
Akiko Obata ◽  
Megumi Sasaki ◽  
Toshihiro Kasuga
Keyword(s):  
Tissue Engineering ◽  
Compressive Strength ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Glass Ceramic ◽  
Tricalcium Phosphate ◽  
Ceramic Composites ◽  
Calcium Pyrophosphate ◽  
Macroporous Glass ◽  
Glass Powders

A macroporous phosphate invert glass ceramic (PIGC) was prepared by dipping polymer sponges in the powder-slurry of the mother glass with a composition of 60CaO-30P2O-3TiO2- 7Na2O in mol%, and subsequent burning off the sponge at 850°C for 1 hr. The macroporous PIGC consists predominantly of ß-tricalcium phosphate (β-TCP) and ß-calcium pyrophosphate, and it has macropores of 500 μm in diameter and porosity of 83 %. Its compressive strength was estimated to be 160 kPa. The PIGC composite containing a large amount of β-TCP was also prepared by heating the mixture of Ca(OH)2 with the mother glass powders of the PIGC. Solubility of the composite was higher than PIGC. The macroporous PIGC and PIGC composite were expected to be applicable in high resorbable scaffolds for bone tissue engineering.

scholarly journals In Vitro and In Vivo Characterization of N-Acetyl-L-Cysteine Loaded Beta-Tricalcium Phosphate Scaffolds

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Yong-Seok Jang ◽  
Phonelavanh Manivong ◽  
Yu-Kyoung Kim ◽  
Kyung-Seon Kim ◽  
Sook-Jeong Lee ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Tricalcium Phosphate ◽  
Water Soluble ◽  
Tetrazolium Salt ◽  
Porous Scaffolds ◽  
Tissue Engineering Application ◽  
Beta Tricalcium Phosphate

Beta-tricalcium phosphate bioceramics are widely used as bone replacement scaffolds in bone tissue engineering. The purpose of this study is to develop beta-tricalcium phosphate scaffold with the optimum mechanical properties and porosity and to identify the effect of N-acetyl-L-cysteine loaded to beta-tricalcium phosphate scaffold on the enhancement of biocompatibility. The various interconnected porous scaffolds were fabricated using slurries containing various concentrations of beta-tricalcium phosphate and different coating times by replica method using polyurethane foam as a passing material. It was confirmed that the scaffold of 40 w/v% beta-tricalcium phosphate with three coating times had optimum microstructure and mechanical properties for bone tissue engineering application. The various concentration of N-acetyl-L-cysteine was loaded on 40 w/v% beta-tricalcium phosphate scaffold. Scaffold group loaded 5 mM N-acetyl-L-cysteine showed the best viability of MC3T3-E1 preosteoblastic cells in the water-soluble tetrazolium salt assay test.

Boron-doped Biphasic Hydroxyapatite/β-Tricalcium Phosphate for Bone Tissue Engineering

2020 ◽  
Author(s):  
Ahmet Engin Pazarçeviren ◽  
Ayşen Tezcaner ◽  
Dilek Keskin ◽  
Serap Topsoy Kolukısa ◽  
Sedat Sürdem ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Tricalcium Phosphate ◽  
Boron Doped

scholarly journals The Regenerative Applicability of Bioactive Glass and Beta-Tricalcium Phosphate in Bone Tissue Engineering: A Transformation Perspective

2019 ◽  
Vol 10 (1) ◽  
pp. 16 ◽  
Author(s):  
Baboucarr Lowe ◽  
Mark P. Ottensmeyer ◽  
Chun Xu ◽  
Yan He ◽  
Qingsong Ye ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bioactive Glass ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Tricalcium Phosphate ◽  
Beta Tricalcium Phosphate ◽  
Engineering Strategy

The conventional applicability of biomaterials in the field of bone tissue engineering takes into consideration several key parameters to achieve desired results for prospective translational use. Hence, several engineering strategies have been developed to model in the regenerative parameters of different forms of biomaterials, including bioactive glass and β-tricalcium phosphate. This review examines the different ways these two materials are transformed and assembled with other regenerative factors to improve their application for bone tissue engineering. We discuss the role of the engineering strategy used and the regenerative responses and mechanisms associated with them.

scholarly journals Microwave-sintered 3D printed tricalcium phosphate scaffolds for bone tissue engineering

2012 ◽  
Vol 7 (8) ◽  
pp. 631-641 ◽  
Author(s):  
Solaiman Tarafder ◽  
Vamsi Krishna Balla ◽  
Neal M Davies ◽  
Amit Bandyopadhyay ◽  
Susmita Bose
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Tricalcium Phosphate ◽  
3D Printed
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