The pressure fluctuation excited by the hydraulic pump can cause serious vibration in aero hydraulic pipeline system, which poses a serious threat to the safety of the aircraft. Therefore, an effective method for predicting the fluid pressure fluctuation and dynamic response of pipeline is strongly recommended. In this paper, a comprehensive model for predicting the dynamic response of pipeline, which includes the Poisson coupling, friction coupling, the vibration damping, Coriolis, and centrifugal forces is proposed. A numerical code is presented to solve the hydraulic pipeline equations. In this code, the hydraulic equations are solved by the method of characteristics and the dynamic equations of pipeline are solved by the finite element method combined with the Newmark algorithm. The numerical code is validated through the comparison of the dynamic response for a typical hydraulic pipeline with experiment. The obtained results indicate that the current combining method of characteristics and finite element method approach can predict the dynamic response of hydraulic pipeline with sufficient accuracy, which can serve as an efficient tool in the design and maintenance of aero hydraulic pipeline.