Influence of CT Window Techniques on Gross Tumor Volume Delineation of Lung Cancer

2011 ◽  
Vol 271-273 ◽  
pp. 973-977
Author(s):  
Juan Wang ◽  
Hui Qun Wu ◽  
Jian Guo Xia ◽  
Le Min Tang

To determine the variation in delineation of the gross tumor volume(GTV) of lung cancer on CT images with different window width(WW) and window level(WL).

2011 ◽  
Vol 271-273 ◽  
pp. 967-972
Author(s):  
Juan Wang ◽  
Jian Guo Xia ◽  
Le Min Tang

To compare the differences of the gross tumor volume(GTV) of lung cancer defined by radiologists and radiation oncologists and evaluate the influence of subjective variability to normal tissue complication probability(NTCP) of heart.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Xiao Chang ◽  
Wei Deng ◽  
Xin Wang ◽  
Zongmei Zhou ◽  
Jun Yang ◽  
...  

Abstract Purpose To investigate the interobserver variability (IOV) in target volume delineation of definitive radiotherapy for thoracic esophageal cancer (TEC) among cancer centers in China, and ultimately improve contouring consistency as much as possible to lay the foundation for multi-center prospective studies. Methods Sixteen cancer centers throughout China participated in this study. In Phase 1, three suitable cases with upper, middle, and lower TEC were chosen, and participants were asked to contour a group of gross tumor volume (GTV-T), nodal gross tumor volume (GTV-N) and clinical target volume (CTV) for each case based on their routine experience. In Phase 2, the same clinicians were instructed to follow a contouring protocol to re-contour another group of target volume. The variation of the target volume was analyzed and quantified using dice similarity coefficient (DSC). Results Sixteen clinicians provided routine volumes, whereas ten provided both routine and protocol volumes for each case. The IOV of routine GTV-N was the most striking in all cases, with the smallest DSC of 0.37 (95% CI 0.32–0.42), followed by CTV, whereas GTV-T showed high consistency. After following the protocol, the smallest DSC of GTV-N was improved to 0.64 (95% CI 0.45–0.83, P = 0.005) but the DSC of GTV-T and CTV remained constant in most cases. Conclusion Variability in target volume delineation was observed, but it could be significantly reduced and controlled using mandatory interventions.


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