Ultrastructural Characterization of Liposomes Using Transmission Electron Microscope

2008 ◽  
Vol 55-57 ◽  
pp. 709-711 ◽  
Author(s):  
Prukswan Chetanachan ◽  
P. Akarachalanon ◽  
D. Worawirunwong ◽  
Pisutti Dararutana ◽  
A. Bangtrakulnonth ◽  
...  

A liposome is a spherical vesicle composed of phospholipids and cholesterol bilayer membrane and contains a core of aqueous solution. Liposomes are polymeric nanoparticles used for drug delivery due to their unique properties. It can carry both hydrophobic and hydrophilic molecules. In this study, we showed the benefit of using transmission electron microscope (TEM) with negative staining technique to investigate the morphology of liposomes produced by thin film method. At the same magnification of micrograph results, we could see the multilamellar vesicles of liposomes in various figures and different sizes.

2017 ◽  
Vol 2 (3) ◽  
pp. 174-185 ◽  
Author(s):  
Hu Zhao ◽  
Bao Qiu ◽  
Haocheng Guo ◽  
Kai Jia ◽  
Zhaoping Liu ◽  
...  

2000 ◽  
Vol 6 (S2) ◽  
pp. 228-229
Author(s):  
M. A. Schofield ◽  
Y. Zhu

Quantitative off-axis electron holography in a transmission electron microscope (TEM) requires careful design of experiment specific to instrumental characteristics. For example, the spatial resolution desired for a particular holography experiment imposes requirements on the spacing of the interference fringes to be recorded. This fringe spacing depends upon the geometric configuration of the TEM/electron biprism system, which is experimentally fixed, but also upon the voltage applied to the biprism wire of the holography unit, which is experimentally adjustable. Hence, knowledge of the holographic interference fringe spacing as a function of applied voltage to the electron biprism is essential to the design of a specific holography experiment. Furthermore, additional instrumental parameters, such as the coherence and virtual size of the electron source, for example, affect the quality of recorded holograms through their effect on the contrast of the holographic fringes.


ACS Nano ◽  
2016 ◽  
Vol 10 (1) ◽  
pp. 1475-1480 ◽  
Author(s):  
Qing Wang ◽  
Ryo Kitaura ◽  
Shoji Suzuki ◽  
Yuhei Miyauchi ◽  
Kazunari Matsuda ◽  
...  

2009 ◽  
Vol 24 (11) ◽  
pp. 3358-3371 ◽  
Author(s):  
Sophie Chausson ◽  
Richard Retoux ◽  
Jean-Michel Rueff ◽  
Loïc LE Pluart ◽  
Pierre-Jean Madec ◽  
...  

This article describes the synthesis and the characterization of a polyamide-12 filled with a nanostructured organic/inorganic titanoniobate hybrid material. The pristine oxide KTiNbO5 has been successfully organomodified by N-alkyl amines via an acido-basic reaction after a cationic exchange step as shown by x-ray diffraction. Transmission electron microscope study and scanning transmission electron microscope observations have been used to describe the change of morphology of the nanofillers before and after processing; the micronic aggregates were changed into single sheets and dispersed in the polymer. Thermomechanical properties of the composites have been determined, and their analyses with structure-properties models are consistent with the exfoliation of the organomodified titanoniobates.


Nano Letters ◽  
2011 ◽  
Vol 11 (12) ◽  
pp. 5184-5188 ◽  
Author(s):  
Ye Lu ◽  
Christopher A. Merchant ◽  
Marija Drndić ◽  
A. T. Charlie Johnson

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