Bone Induction by Controlled Release of BMP-2 from a Biodegradable Hydrogel in Various Animal Species - From Mouse to Non-Human Primate -
2005 ◽
Vol 288-289
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pp. 253-256
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Keyword(s):
The objective of this study is to examine feasibility of biodegradable gelatin hydrogels incorporating bone morphogenetic protein (BMP)-2 in inducing bone regeneration at a bone defect of non-human primates and rabbits considering their BMP-2 release profiles. As a result, controlled release by the hydrogel system enabled BMP-2 to induce successful bone regeneration in non-human primates even at the BMP-2 dose as low as that for rabbit case (0.034 mg of BMP-2/cm3 of hydrogel).
2011 ◽
Vol 6
(4)
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pp. 291-298
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2005 ◽
pp. 253-256
Keyword(s):
2007 ◽
Vol 117
(3)
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pp. 380-386
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2013 ◽
Vol 9
(9)
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pp. 8374-8383
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2016 ◽
Vol 87
(4)
◽
pp. 470-480
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