Targeting of Liver Mannan-Binding Lectin–Associated Serine Protease-3 with RNA Interference Ameliorates Disease in a Mouse Model of Rheumatoid Arthritis

Nirmal K. Banda; Dhruv Desai; Robert I. Scheinman; Rasmus Pihl; Hideharu Sekine; Teizo Fujita; Vibha Sharma; Annette G. Hansen; Peter Garred; Steffen Thiel; Anna Borodovsky; V. Michael Holers

doi:10.4049/immunohorizons.1800053

Targeting of Liver Mannan-Binding Lectin–Associated Serine Protease-3 with RNA Interference Ameliorates Disease in a Mouse Model of Rheumatoid Arthritis

ImmunoHorizons ◽

10.4049/immunohorizons.1800053 ◽

2018 ◽

Vol 2 (8) ◽

pp. 274-295 ◽

Cited By ~ 7

Author(s):

Nirmal K. Banda ◽

Dhruv Desai ◽

Robert I. Scheinman ◽

Rasmus Pihl ◽

Hideharu Sekine ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Rna Interference ◽

Mouse Model ◽

Serine Protease ◽

Mannan Binding Lectin ◽

Binding Lectin

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siRNA-mediated targeting of hepatocyte mannan-binding lectin-associated serine protease-3 for the treatment of murine collagen-antibody-inducsed arthritis (CAIA), a model for human rheumatoid arthritis

Molecular Immunology ◽

10.1016/j.molimm.2017.06.129 ◽

2017 ◽

Vol 89 ◽

pp. 161 ◽

Cited By ~ 1

Author(s):

Nirmal K. Banda ◽

Dhruv Desai ◽

Adam Casterano ◽

Robert I. Scheinman ◽

Sumitra Acharya ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Serine Protease ◽

Human Rheumatoid Arthritis ◽

Mannan Binding Lectin ◽

Binding Lectin

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Targeted inhibition by RNA interference-mediated gene silencing of mannan-binding lectin-associated serine protease (MASP)-1/3 expression attenuates collagen antibody-induced arthritis (CAIA)

Immunobiology ◽

10.1016/j.imbio.2016.06.017 ◽

2016 ◽

Vol 221 (10) ◽

pp. 1131-1132

Author(s):

Nirmal K. Banda ◽

Sumitra Acharya ◽

Robert I. Scheinman ◽

Gaurav Mehta ◽

Minoru Takahashi ◽

...

Keyword(s):

Rna Interference ◽

Gene Silencing ◽

Serine Protease ◽

Targeted Inhibition ◽

Mannan Binding Lectin ◽

Binding Lectin

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Mannan-Binding Lectin–Associated Serine Protease 1/3 Cleavage of Pro–Factor D into Factor D In Vivo and Attenuation of Collagen Antibody-Induced Arthritis through Their Targeted Inhibition by RNA Interference–Mediated Gene Silencing

The Journal of Immunology ◽

10.4049/jimmunol.1600719 ◽

2016 ◽

Vol 197 (9) ◽

pp. 3680-3694 ◽

Cited By ~ 10

Author(s):

Nirmal K. Banda ◽

Sumitra Acharya ◽

Robert I. Scheinman ◽

Gaurav Mehta ◽

Marilyne Coulombe ◽

...

Keyword(s):

Rna Interference ◽

Gene Silencing ◽

Serine Protease ◽

Targeted Inhibition ◽

Mannan Binding Lectin ◽

Binding Lectin

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Faculty Opinions recommendation of Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004704.370795 ◽

2006 ◽

Author(s):

Masaru Nonaka

Keyword(s):

Growth Factor ◽

Serine Protease ◽

Synthetic Peptides ◽

Binding Protein ◽

Insulin Like Growth Factor ◽

Factor Binding ◽

Mannan Binding Lectin ◽

Binding Lectin

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Faculty Opinions recommendation of Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.10191956.10981054 ◽

2011 ◽

Author(s):

Jens Christian Jensenius

Keyword(s):

Reperfusion Injury ◽

Serine Protease ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Mannan Binding Lectin ◽

Gastrointestinal Ischemia ◽

Binding Lectin

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Faculty Opinions recommendation of Composition of the lectin pathway of complement in Gallus gallus: absence of mannan-binding lectin-associated serine protease-1 in birds.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1025509.305732 ◽

2005 ◽

Author(s):

Masaru Nonaka

Keyword(s):

Serine Protease ◽

Gallus Gallus ◽

Lectin Pathway ◽

Mannan Binding Lectin ◽

Binding Lectin

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Mannan-Binding Lectin Serine Protease 1

Encyclopedia of Signaling Molecules ◽

10.1007/978-3-319-67199-4_102146 ◽

2018 ◽

pp. 2934-2934

Keyword(s):

Serine Protease ◽

Mannan Binding Lectin ◽

Binding Lectin

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Diabetes-induced Changes in Mannan-binding Lectin Levels and Complement Activation in a Mouse Model of Type 1 Diabetes

Scandinavian Journal of Immunology ◽

10.1111/sji.12027 ◽

2013 ◽

Vol 77 (3) ◽

pp. 187-194 ◽

Cited By ~ 16

Author(s):

J. A. Østergaard ◽

M. Bjerre ◽

F. Dagnaes-Hansen ◽

T. K. Hansen ◽

S. Thiel ◽

...

Keyword(s):

Type 1 Diabetes ◽

Mouse Model ◽

Complement Activation ◽

Induced Changes ◽

Mannan Binding Lectin ◽

Binding Lectin

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Serum concentrations of lectin-pathway components in healthy neonates, children and adults: mannan-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2)

Pediatric Allergy and Immunology ◽

10.1111/j.1399-3038.2010.01104.x ◽

2011 ◽

Vol 22 (4) ◽

pp. 424-430 ◽

Cited By ~ 68

Author(s):

Seraina Sallenbach ◽

Steffen Thiel ◽

Christoph Aebi ◽

Margrith Otth ◽

Susanna Bigler ◽

...

Keyword(s):

Serine Protease ◽

Lectin Pathway ◽

Serum Concentrations ◽

Mannan Binding Lectin ◽

Binding Lectin

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Mannan-binding lectin-associated serine protease-2 (MASP-2) in a large cohort of neonates and its clinical associations

Molecular Immunology ◽

10.1016/j.molimm.2009.02.022 ◽

2009 ◽

Vol 46 (8-9) ◽

pp. 1696-1701 ◽

Cited By ~ 24

Author(s):

Anna St. Swierzko ◽

Maciej Cedzynski ◽

Iwona Domzalska-Popadiuk ◽

Shirley L. MacDonald ◽

Monika Borkowska-Klos ◽

...

Keyword(s):

Serine Protease ◽

Large Cohort ◽

Clinical Associations ◽

Mannan Binding Lectin ◽

Binding Lectin

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