A Case of Extra-Adrenal Pheochromocytoma with Abdominal Colic and Paroxysmal Hypertension

1993 ◽  
Vol 23 (4) ◽  
pp. 621
Author(s):  
Jeong Seong Kang ◽  
Soo Yeon Won ◽  
Il Mun Jeon ◽  
Myoung Kyu Jang ◽  
Suck Chei Choi ◽  
...  
Keyword(s):  
Abdominal Colic ◽  
Paroxysmal Hypertension ◽  
Adrenal Pheochromocytoma

scholarly journals Acute Heart Failure as a First Presentation of Pheochromocytoma Complicated with “Inverted” Takotsubo Syndrome

2020 ◽  
Vol 2020 ◽  
pp. 1-4 ◽  
Author(s):  
Jerrold Spapen ◽  
Jeroen de Filette ◽  
Stijn Lochy ◽  
Herbert Spapen
Keyword(s):  
Heart Failure ◽  
Pulmonary Oedema ◽  
Acute Heart Failure ◽  
Chromaffin Cells ◽  
Myocardial Injury ◽  
Takotsubo Syndrome ◽  
Healthy Patient ◽  
Lv Dysfunction ◽  
Paroxysmal Hypertension ◽  
Adrenal Pheochromocytoma

Takotsubo syndrome is a rare but emerging form of acute reversible myocardial injury characterized by transient systolic LV dysfunction, often related to emotional or physical stress. Pheochromocytoma is increasingly recognised as another possible trigger. Pheochromocytoma is a rare catecholamine-secreting tumour arising from chromaffin cells within the adrenal medulla or extra-adrenal paraganglia. The pathognomonic quartet of paroxysmal hypertension, palpitations, headache, and diaphoresis is rarely present, and diagnosis is often delayed. We describe a 43-year-old formerly healthy patient with an adrenal pheochromocytoma, presenting as an “inverted” takotsubo syndrome complicated with acute heart failure and pulmonary oedema.

48: Single Center Comparison of Laparoscopic and Open Surgery for Adrenal Pheochromocytoma

2007 ◽  
Vol 177 (4S) ◽  
pp. 17-17
Author(s):  
Monish Aron ◽  
Georges-Pascal Haber ◽  
Jose R. Colombo ◽  
Troy R. Gianduzzo ◽  
Jason M. Hafron ◽  
...  
Keyword(s):  
Open Surgery ◽  
Single Center ◽  
Adrenal Pheochromocytoma

Recurrent adrenal pheochromocytoma - a benign condition?

2016 ◽  
Author(s):  
Adriana de Sousa Lages ◽  
Patricia Oliveira ◽  
Dircea Rodrigues ◽  
Gracinda Costa ◽  
Maria Joao Martins ◽  
...  
Keyword(s):  
Benign Condition ◽  
Adrenal Pheochromocytoma

scholarly journals Autonomic dysreflexia associated with cervical spinal cord gliofibroma: case report

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hiroyuki Mizuno ◽  
Fumiaki Honda ◽  
Hayato Ikota ◽  
Yuhei Yoshimoto
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Spinal Cord Tumor ◽  
Autonomic Dysreflexia ◽  
Tumor Biopsy ◽  
Intramedullary Lesion ◽  
First Case ◽  
Cord Injury ◽  
Paroxysmal Hypertension ◽  
Upper And Lower Extremities

Abstract Background Autonomic dysreflexia (AD) is an abnormal reflex of the autonomic nervous system normally observed in patients with spinal cord injury from the sixth thoracic vertebra and above. AD causes various symptoms including paroxysmal hypertension due to stimulus. Here, we report a case of recurrent AD associated with cervical spinal cord tumor. Case presentation The patient was a 57-year-old man. Magnetic resonance imaging revealed an intramedullary lesion in the C2, C6, and high Th12 levels. During the course of treatment, sudden loss of consciousness occurred together with abnormal paroxysmal hypertension, marked facial sweating, left upward conjugate gaze deviation, ankylosis of both upper and lower extremities, and mydriasis. Seizures repeatedly occurred, with symptoms disappearing after approximately 30 min. AD associated with cervical spinal cord tumor was diagnosed. Histological examination by tumor biopsy confirmed the diagnosis of gliofibroma. Radiotherapy was performed targeting the entire brain and spinal cord. The patient died approximately 3 months after treatment was started. Conclusions AD is rarely associated with spinal cord tumor, and this is the first case associated with cervical spinal cord gliofibroma. AD is important to recognize, since immediate and appropriate response is required.

scholarly journals Characterization of neuroendocrine tumors in heterozygous mutant MENX rats: a novel model of invasive medullary thyroid carcinoma

2018 ◽  
Vol 25 (2) ◽  
pp. 145-162 ◽  
Author(s):  
Sara Molatore ◽  
Andrea Kügler ◽  
Martin Irmler ◽  
Tobias Wiedemann ◽  
Frauke Neff ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Early Stage ◽  
Pituitary Tumors ◽  
Transcriptome Profiling ◽  
Thyroid Neoplasms ◽  
Recessive Trait ◽  
Wild Type ◽  
Incurable Cancer ◽  
Medullary Thyroid ◽  
Adrenal Pheochromocytoma

Rats affected by the MENX syndrome spontaneously develop multiple neuroendocrine tumors (NETs) including adrenal, pituitary and thyroid gland neoplasms. MENX was initially reported to be inherited as a recessive trait and affected rats were found to be homozygous for the predisposingCdkn1bmutation encoding p27. We here report that heterozygous MENX-mutant rats (p27+/mut) develop the same spectrum of NETs seen in the homozygous (p27mut/mut) animals but with slower progression. Consequently, p27+/mut rats have a significantly shorter lifespan compared with their wild-type (p27+/+) littermates. In the tumors of p27+/mut rats, the wild-typeCdkn1ballele is neither lost nor silenced, implying that p27 is haploinsufficient for tumor suppression in this model. Transcriptome profiling of rat adrenal (pheochromocytoma) and pituitary tumors having different p27 dosages revealed a tissue-specific, dose-dependent effect of p27 on gene expression. In p27+/mut rats, thyroid neoplasms progress to invasive and metastatic medullary thyroid carcinomas (MTCs) accompanied by increased calcitonin levels, as in humans. Comparison of expression signatures of late-stage vs early-stage MTCs from p27+/mut rats identified genes potentially involved in tumor aggressiveness. The expression of a subset of these genes was evaluated in human MTCs and found to be associated with aggressive RET-M918T-positive tumors. Altogether, p27 haploinsufficiency in MENX rats uncovered a novel, representative model of invasive and metastatic MTC exploitable for translational studies of this often aggressive and incurable cancer.

Outcomes of resection of extra-adrenal pheochromocytomas/paragangliomas in the laparoscopic era: a comparison with adrenal pheochromocytoma

2012 ◽  
Vol 27 (2) ◽  
pp. 428-433 ◽  
Author(s):  
Trudie A. Goers ◽  
Michael Abdo ◽  
Jeffrey F. Moley ◽  
Brent D. Matthews ◽  
Mary Quasebarth ◽  
...  
Keyword(s):  
Adrenal Pheochromocytoma
Sign in / Sign up

Export Citation Format

Share Document