scholarly journals Association between Body Mass Index and Clinical Outcomes of Peripheral Artery Disease after Endovascular Therapy: Data from K-VIS ELLA Registry

2021 ◽  
Vol 51 ◽  
Author(s):  
Chewan Lim ◽  
Hoyoun Won ◽  
Young-Guk Ko ◽  
Seung-Jun Lee ◽  
Chul-Min Ahn ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Clinical Outcomes ◽  
Body Mass ◽  
Peripheral Artery Disease ◽  
Endovascular Therapy ◽  
Peripheral Artery ◽  
Artery Disease

scholarly journals Impact of Objective Malnutrition Status on the Clinical Outcomes in Patients With Peripheral Artery Disease Following Endovascular Therapy

2018 ◽  
Vol 82 (3) ◽  
pp. 847-856 ◽  
Author(s):  
Miyuki Yokoyama ◽  
Tetsu Watanabe ◽  
Yoichiro Otaki ◽  
Ken Watanabe ◽  
Taku Toshima ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Peripheral Artery Disease ◽  
Endovascular Therapy ◽  
Peripheral Artery ◽  
Artery Disease

Body mass index and outcome in patients with coronary, cerebrovascular, or peripheral artery disease: findings from the FRENA registry

2009 ◽  
Vol 16 (4) ◽  
pp. 457-463 ◽  
Author(s):  
Raquel Barba ◽  
Josep Bisbe ◽  
José Nicolas Alcalá Pedrajas ◽  
Jesús Toril ◽  
Rafael Monte ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cerebrovascular Disease ◽  
Body Mass ◽  
Peripheral Artery Disease ◽  
Cardiovascular Mortality ◽  
Inverse Correlation ◽  
Limb Ischemia ◽  
Arterial Disease ◽  
Peripheral Artery ◽  
Artery Disease

Background The relationship between body mass index (BMI) and mortality in patients with established arterial disease remains controversial. Methods FRENA is an ongoing, observational registry of consecutive outpatients with coronary artery disease (CAD), cerebrovascular disease, or peripheral artery disease (PAD). We examined the prognostic importance of accepted BMI categories on outcome among patients in the FRENA registry. Results In April 2008, 2274 patients (mean age, 66 years) had been enrolled, of whom 14 (0.6%) were underweight; 533 (23%) normal; 1051 (46%) overweight; and 676 (30%) were obese. Over a mean follow-up of 14 months, the incidence of major cardiovascular events (myocardial infarction, ischemic stroke, or critical limb ischemia) per 100 patient-years was: 7.1 [95% confidence interval (CI): 0.4–35]; 11 (95% CI: 8.4–14); 6.9 (95% CI: 5.6–8.5); and 8.5 (95% CI: 6.6–11), respectively. Their cardiovascular mortality was: 7.1 (95% CI: 0.4–35); 4.1 (95% CI: 5.9–11); 1.3 (95% CI: 0.9–2.3); and 1.5 (95% CI: 1.4–3.5), respectively. On multivariate analysis, the hazard ratio for cardiovascular mortality was: 2.2 (95% CI: 0.3–17); 1.0 (reference); 0.37 (95% CI: 0.20–0.69); and 0.37 (95% CI: 0.18–0.73), respectively. Survival benefit was only found in patients with CAD or PAD. Weight loss had little influence on outcome. Conclusion Patients with CAD or PAD (not those with cerebrovascular disease) have an inverse correlation between BMI and cardiovascular mortality, even after adjusting for confounding variables.

scholarly journals Body mass index and peripheral artery disease

2020 ◽  
Vol 292 ◽  
pp. 31-36 ◽  
Author(s):  
Sean P. Heffron ◽  
Aeshita Dwivedi ◽  
Caron B. Rockman ◽  
Yuhe Xia ◽  
Yu Guo ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Peripheral Artery Disease ◽  
Peripheral Artery ◽  
Artery Disease

Association Between Underweight Body Mass Index and In-Hospital Outcome in Patients Undergoing Endovascular Interventions for Peripheral Artery Disease: A Propensity Score Matching Analysis

2019 ◽  
Vol 26 (3) ◽  
pp. 411-417 ◽  
Author(s):  
Homam Moussa Pacha ◽  
Yasser Al-khadra ◽  
Fahed Darmoch ◽  
Mohamad Soud ◽  
Amir Kaki ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Propensity Score ◽  
Propensity Score Matching ◽  
Body Mass ◽  
Peripheral Artery Disease ◽  
Peripheral Artery ◽  
Propensity Score Matching Analysis ◽  
Significant Difference ◽  
Low Bmi ◽  
Artery Disease

Purpose: To investigate in-hospital outcomes after endovascular therapy (EVT) in patients with severe peripheral artery disease (PAD) who had a low body mass index (BMI, kg/m2) compared to those with normal BMI. Materials and Methods: Using weighted data from the National Inpatient Sample (NIS) database between 2002 and 2014 and ICD-9 codes, 2614 patients were identified who were aged ≥18 years and underwent EVT for PAD in the lower limb vessels. EVT was defined as angioplasty, atherectomy, and/or stenting. After excluding individuals with BMI >24, there were 807 (31%) normal-weight (BMI 19–24) patients and 1807 (69%) underweight (BMI <19) individuals. All patients in both groups were matched for baseline demographic and clinical characteristics and critical limb ischemia in a 1:1 propensity score matching analysis using the nearest neighbor method. Results: Propensity score matching produced 2 groups of 685 patients that differed only in the incidence of chronic lung disease, which was more frequent in low-BMI patients (p=0.04). Patients with low BMI had a higher incidence of in-hospital mortality (4.8% vs 1.2%, p<0.001), major adverse cardiovascular events (composite of death, myocardial infarction, or stroke) (7.9% vs 4.1%, p=0.003), open bypass surgery (9.1% vs 6.0%, p=0.03), and infection (14.6% vs 10.5%, p=0.02) compared with the normal-BMI group. There was no significant difference in the incidence of vascular complications (p=0.31), major bleeding (p=0.17), major amputation (p=0.35), or acute kidney injury (p=0.09) between the low- and normal-BMI groups. Conclusion: Low-BMI patients with PAD have worse in-hospital survival and more adverse outcomes after EVT.

scholarly journals Midlife Cardiorespiratory Fitness and the Development of Peripheral Artery Disease in Later Life

2021 ◽  
Author(s):  
Neil Keshvani ◽  
Benjamin Willis ◽  
David Leonard ◽  
Ang Gao ◽  
Laura DeFina ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Cardiorespiratory Fitness ◽  
Peripheral Artery Disease ◽  
Lower Risk ◽  
Later Life ◽  
Peripheral Artery ◽  
Metabolic Equivalent ◽  
Metabolic Equivalent Task ◽  
Artery Disease

Background Data are sparse on the prospective associations between physical activity and incidence of lower extremity peripheral artery disease (PAD). Methods and Results Linking participant data from the CCLS (Cooper Center Longitudinal Study) to Medicare claims files, we studied 19 023 participants with objectively measured midlife cardiorespiratory fitness through maximal effort on the Balke protocol who survived to receive Medicare coverage between 1999 and 2009. The study aimed to determine the association between midlife cardiorespiratory fitness and incident PAD with proportional hazards intensity models, adjusted for age, sex, body mass index, and other covariates, to PAD failure time data. During 121 288 person‐years of Medicare follow‐up, we observed 805 PAD‐related hospitalizations/procedures among 19 023 participants (21% women, median age 50 years). Lower midlife fitness was associated with a higher rate of incident PAD in patients aged 65 years and older (low fit [quintile 1]: 11.4, moderate fit [quintile 2 to 3]: 7.8, and high fit [quintile 4 to 5]: 5.7 per 1000 person years). After multivariable adjustment for common predictors of incident PAD such as age, body mass index, hypertension, and diabetes, these findings persisted. Lower risk for PAD per greater metabolic equivalent task of fitness was observed (hazard ratio [HR], 0.93 [95% CI, 0.90–0.97]; P <0.001). Among a subset of patients with an additional fitness assessment, each 1 metabolic equivalent task increase from baseline fitness was associated with decreased risk of incident PAD (HR, 0.90 [95% CI, 0.82–0.99]; P =0.03). Conclusions Cardiorespiratory fitness in healthy, middle‐aged adults is associated with lower risk of incident PAD in later life, independent of other predictors of incident PAD.

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