d-Limonene: a bioactive food component from citrus and evidence for a potential role in breast cancer prevention and treatment

10.4081/14 ◽  
2011 ◽  
Vol 5 (1) ◽  
Author(s):  
Jessica A. Miller ◽  
Patricia A. Thompson ◽  
Iman A. Hakim ◽  
H.-H. Sherry Chow ◽  
Cynthia A. Thomson
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Potential Role ◽  
Breast Cancer Prevention ◽  
Food Component ◽  
Prevention And Treatment ◽  
Bioactive Food Component

d-Limonene: a bioactive food component from citrus and evidence for a potential role in breast cancer prevention and treatment

2010 ◽  
Vol 5 (1) ◽  
pp. 31-42 ◽  
Author(s):  
Jessica A. Miller ◽  
Patricia A. Thompson ◽  
Iman A. Hakim ◽  
H.-H. Sherry Chow ◽  
Cynthia A. Thomson
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Potential Role ◽  
Breast Cancer Prevention ◽  
Food Component ◽  
Prevention And Treatment ◽  
Bioactive Food Component

scholarly journals d-Limonene: a bioactive food component from citrus and evidence for a potential role in breast cancer prevention and treatment

2011 ◽  
pp. 31-42
Author(s):  
Jessica A. Miller ◽  
Patricia A. Thompson ◽  
Iman A. Hakim ◽  
H.-H. Sherry Chow ◽  
Cynthia A. Thomson
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Immune Modulation ◽  
Wide Spectrum ◽  
Perillyl Alcohol ◽  
Potent Effect ◽  
Food Component ◽  
Citrus Peel ◽  
Anti Cancer ◽  
Prevention And Treatment

Although limited, observations from cell culture, animal, and epidemiological studies support the presence of anti-cancer properties in citrus peel and the primary bioactive food constituent, d-limonene. Early evidence from animal models suggests that when ingested, d-limonene exhibits a wide spectrum of biologic activity including chemotherapeutic and chemopreventive effects. In some of these early models, an analog of d-limonene, perillyl alcohol, demonstrated a more potent effect than d-limonene itself. Yet, when perillyl alcohol advanced to clinical trials, several trials were ended early due to doselimiting toxicities. Alternatively, oral d-limonene administration in humans is well tolerated even at high doses supporting its investigation as a potential bioactive for cancer prevention. Though the exact mechanisms of action of d-limonene are unclear, immune modulation and antiproliferative effects are commonly reported. Here, we review the pre-clinical evidence for d-limonene’s anticancer mechanisms, bioavailability, and safety, as well as the evidence for anti-cancer effects in humans, focusing on studies relevant to its use in the prevention and treatment of breast cancer.

Use of potential dietary phytochemicals to target miRNA: Promising option for breast cancer prevention and treatment?

2017 ◽  
Vol 28 ◽  
pp. 177-193 ◽  
Author(s):  
Md. Abu Sayeed ◽  
Massimo Bracci ◽  
Raffaella Lazzarini ◽  
Marco Tomasetti ◽  
Monica Amati ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Breast Cancer Prevention ◽  
Prevention And Treatment ◽  
Dietary Phytochemicals

scholarly journals Herbal Remedies for Breast Cancer Prevention and Treatment

2020 ◽  
Author(s):  
Yahyea Baktiar Laskar ◽  
Romen Meitei Lourembam ◽  
Pranab Behari Mazumder
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Breast Cancer Prevention ◽  
Herbal Remedies ◽  
Prevention And Treatment

scholarly journals Recent advances of curcumin and its analogues in breast cancer prevention and treatment

RSC Advances ◽  
2015 ◽  
Vol 5 (92) ◽  
pp. 75575-75588 ◽  
Author(s):  
Charlotta D. Mock ◽  
Brian C. Jordan ◽  
Chelliah Selvam
Keyword(s):  
Breast Cancer ◽  
Cancer Treatment ◽  
Cancer Prevention ◽  
Breast Cancer Treatment ◽  
Delivery Systems ◽  
Breast Cancer Prevention ◽  
Curcumin Analogues ◽  
Prevention And Treatment ◽  
Recent Developments ◽  
Novel Delivery Systems

This review focuses on recent developments in the use of curcumin, curcumin analogues, and novel delivery systems as a preventive and therapeutic method for breast cancer treatment.

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