scholarly journals Metastatic lung adenocarcinoma in appearance of diminutive colonic polyp

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Bora Aktaş ◽  
Ferdane Sapmaz ◽  
Sebahat Başyiğit ◽  
Metin Uzman
Keyword(s):  
Lung Adenocarcinoma ◽  
Distant Metastasis ◽  
Clinical Case ◽  
Colonic Polyp ◽  
Initial Diagnosis ◽  
Primary Adenocarcinoma ◽  
Colonic Metastasis ◽  
Lung Cancers ◽  
Adenocarcinoma Of The Lung ◽  
Metastatic Lung

Although about 50% of lung cancers have distant metastasis at the time of initial diagnosis, colonic metastases are extremely rare. This report presents a rare clinical case of colonic metastasis from primary adenocarcinoma of the lung.

scholarly journals Isolated colonic metastasis two years after resection of stage IA primary adenocarcinoma of the lung: A case report

2018 ◽  
Vol 25 ◽  
pp. 86-88
Author(s):  
Stylianos Vittorakis ◽  
Georgia Giannakopoulou ◽  
Konstantinos Konstantinides ◽  
Anna Daskalaki ◽  
Konstantinos Samitas
Keyword(s):  
Case Report ◽  
Primary Adenocarcinoma ◽  
Colonic Metastasis ◽  
Adenocarcinoma Of The Lung ◽  
Stage Ia

scholarly journals Metastatic Lung Adenocarcinoma Mimicking Colonic Polyp

2012 ◽  
Vol 107 ◽  
pp. S459
Author(s):  
Razvi Razack ◽  
Nishith Patel ◽  
Shamik Shah ◽  
Dharmesh Kaswala ◽  
Zamir Brelvi
Keyword(s):  
Lung Adenocarcinoma ◽  
Colonic Polyp ◽  
Metastatic Lung

scholarly journals Metastatic Lung Adenocarcinoma Presenting as Diminutive Colonic Polyp

2017 ◽  
Vol 112 ◽  
pp. S992
Author(s):  
Mohammad Maysara Asfari ◽  
Thomas Plesec ◽  
Prashanthi N. Thota
Keyword(s):  
Lung Adenocarcinoma ◽  
Colonic Polyp ◽  
Metastatic Lung

Colonic metastasis from a primary adenocarcinoma of the lung presenting with acute abdominal pain

2012 ◽  
Vol 44 (6) ◽  
pp. e11 ◽  
Author(s):  
Paolo Pozzato ◽  
Angela Salerno ◽  
Alessandra Cancellieri ◽  
Maurizio Ventrucci
Keyword(s):  
Abdominal Pain ◽  
Acute Abdominal Pain ◽  
Primary Adenocarcinoma ◽  
Colonic Metastasis ◽  
Adenocarcinoma Of The Lung

scholarly journals Metastatic lung adenocarcinoma mimicking a colonic polyp

2013 ◽  
Vol 5 (4) ◽  
pp. 306 ◽  
Author(s):  
ShamikS Shah ◽  
RazviM Razack ◽  
ValerieA Fitzhugh ◽  
ZamirS Brelvi ◽  
DharmeshH Kaswala ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Colonic Polyp ◽  
Metastatic Lung

Primary adenocarcinoma of the lung - histological subtypes and outcome after surgery, using the IASLC/ATS/ERS classification of lung adenocarcinoma

Apmis ◽  
2016 ◽  
Vol 124 (5) ◽  
pp. 384-392 ◽  
Author(s):  
Gudrun Nina Oskarsdottir ◽  
Johannes Bjornsson ◽  
Steinn Jonsson ◽  
Helgi J Isaksson ◽  
Tomas Gudbjartsson
Keyword(s):  
Lung Adenocarcinoma ◽  
Primary Adenocarcinoma ◽  
Histological Subtypes ◽  
Adenocarcinoma Of The Lung

scholarly journals A novel GHR-ALK fusion gene in a patient with metastatic lung adenocarcinoma and its response to crizotinib: a case report

2021 ◽  
Vol 49 (9) ◽  
pp. 030006052110446
Author(s):  
Xue Pan ◽  
Anyuan Zhong ◽  
Yufei Xing ◽  
Xi Li ◽  
Haiwei Du ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Growth Hormone Receptor ◽  
Kinase Inhibitors ◽  
Fusion Gene ◽  
Fusion Partner ◽  
Alk Rearrangement ◽  
Lung Cancers ◽  
Anaplastic Lymphoma ◽  
Metastatic Lung ◽  
Generation Sequencing

Anaplastic lymphoma kinase ( ALK) rearrangement occurs in approximately 5% of non-small cell lung cancers (NSCLCS), and EML4-ALK is the most commonly observed ALK fusion variant in NSCLC. However, growth hormone receptor ( GHR) as the fusion partner for ALK and the clinical response to ALK tyrosine kinase inhibitors in patients with metastatic lung adenocarcinoma (LUAD) who carry the GHR-ALK variant have not been documented. This case describes a 63-year-old woman diagnosed with metastatic LUAD. Immunohistochemistry revealed positive ALK expression, and the patient was treated with crizotinib. After 3 weeks of treatment, the patient had a partial response. Because of treatment-related adverse events, the dose of crizotinib was reduced. After 3.7 months, computed tomography uncovered disease progression. Next-generation sequencing identified a novel GHR-ALK fusion in the plasma of the patient. The patient was treated again with crizotinib, but the disease progressed again 2 months later. Then, the patient received chemotherapy. She succumbed to her disease 11 months after the initial diagnosis. Our work provides evidence supporting the use of crizotinib in patients with metastatic LUAD harboring GHR-ALK.

scholarly journals Metastatic lung adenocarcinoma presenting as diminutive colonic polyp

2018 ◽  
Vol 2 ◽  
pp. 14-14
Author(s):  
Prashanthi N. Thota ◽  
Thomas Plesec
Keyword(s):  
Lung Adenocarcinoma ◽  
Colonic Polyp ◽  
Metastatic Lung

The tyrosine kinase TEK is differentially expressed in non-small cell lung adenocarcinomas.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
United States ◽  
Tyrosine Kinase ◽  
Lung Adenocarcinoma ◽  
Microarray Data ◽  
The United States ◽  
Small Cell ◽  
Small Cell Lung ◽  
Significant Differential Expression ◽  
Lung Cancers ◽  
Lung Adenocarcinomas

Non-small cell lung adenocarcinoma (NSCLC) is a leading cause of death in the United States and worldwide (1, 2). We mined published microarray data (3, 4, 5) to discover genes associated with NSCLC. We identified significant differential expression of the tyrosine kinase TEK in tumors from patients with NSCLC. TEK may be of relevance to the initiation, progression or maintenance of non-small cell lung cancers.

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