scholarly journals Cerebral venous thrombosis: diagnosis dilemma

2011 ◽  
Vol 3 (3) ◽  
pp. 13 ◽  
Author(s):  
Pipat Chiewvit ◽  
Siriwan Piyapittayanan ◽  
Niphon Poungvarin

Cerebral venous thrombosis is increasing common disease in daily practice with sharing clinical nonspecific symptoms. This disorder is potentially lethal but treatable, oftenly it was overlooked in both clinical and radiologic in routine practice.  Whenever, clinical suspected, prompt investigation by noninvasive imaging such as conventional technique of CT, MR or advanced modilities such as CTV, MRV will helpful in prompt diagnosis and treatment. These imaging modalities may reveal either direct sign( visualization of intraluminal clot) and indirect signs ( paranchymatous change, intracranial hemorrhage). By using of effective treatment will improve the prognosis of the patient. This review summarizes insights into etiology, incidence, imaging modalities and current of the treatment.<p> </p>

2015 ◽  
Vol 157 (10) ◽  
pp. 1679-1680 ◽  
Author(s):  
Raghvendra Ramdasi ◽  
Amit Mahore ◽  
Juhi Kawale ◽  
Smita Thorve

2021 ◽  
pp. 239698732110594
Author(s):  
Antonio Ochoa-Ferraro ◽  
Subadra Wanninayake ◽  
Charlotte Dawson ◽  
Adam Gerrard ◽  
Mary Anne Preece ◽  
...  

Background Cerebral venous thrombosis (CVT) is an important cause of stroke particularly in younger patients and potentially fatal if diagnosis is delayed. The presentation of symptoms is highly variable and consequently the diagnosis and underlying cause is often delayed or overlooked. Homocystinuria, a rare autosomal recessive disorder is an identified risk factor for CVT. Purpose A timely diagnosis and treatment of the underlying cause of CVT could result in improved outcome and prevent further events. This case series describes the clinical course of six adults presented with unprovoked CVT, in whom the diagnosis of underlying homocystinuria was delayed with adverse consequences. We aim to highlight the importance of recognising homocystinuria as an underlying cause of CVT and offer a practical approach to the diagnosis and management. Methods This is a retrospective case series of a cohort of 30 consecutive patients seen in a UK tertiary referral centre. Result Six out of 30 patients presented with CVT prior to homocystinuria diagnosis. The mean and range of age at the time of the first CVT episode was 22.6 (range 11–31) years. The mean ±SD age at diagnosis of homocystinuria as the underlying cause was 26 ± 4.2 years. The time between first CVT and diagnosis of homocystinuria ranged from 1.6 to 11 years resulting in a delay to introduction of effective treatment and, in some cases, a further large vessels thrombotic event. Conclusion Physician awareness of homocystinuria as an underlying cause for an unprovoked CVT will facilitate timely introduction of effective treatment to prevent a further event.


2020 ◽  
Vol 267 (11) ◽  
pp. 3292-3298
Author(s):  
K. Afifi ◽  
G. Bellanger ◽  
P. J. Buyck ◽  
S. M. Zuurbier ◽  
C. G. Esperon ◽  
...  

2019 ◽  
Vol 140 (6) ◽  
pp. 435-442 ◽  
Author(s):  
Banafsheh Shakibajahromi ◽  
Afshin Borhani‐Haghighi ◽  
Mehrnaz Ghaedian ◽  
Farnia Feiz ◽  
Hossein Molavi Vardanjani ◽  
...  

2016 ◽  
Vol 25 (9) ◽  
pp. 2312-2316 ◽  
Author(s):  
Michael A. Pizzi ◽  
David A. Alejos ◽  
Jason L. Siegel ◽  
Betty Y.S. Kim ◽  
David A. Miller ◽  
...  

2020 ◽  
Vol 267 (11) ◽  
pp. 3299-3300
Author(s):  
K. Afifi ◽  
G. Bellanger ◽  
P. J. Buyck ◽  
S. M. Zuurbier ◽  
C. Garcia-Esperon ◽  
...  

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
David García-Azorín ◽  
Thien Phu Do ◽  
Andreas R. Gantenbein ◽  
Jakob Møller Hansen ◽  
Marcio Nattan P. Souza ◽  
...  

Abstract Background Headache is a frequent symptom following COVID-19 immunization with a typical onset within days post-vaccination. Cases of cerebral venous thrombosis (CVT) have been reported in adenovirus vector-based COVID-19 vaccine recipients. Findings We reviewed all vaccine related CVT published cases by April 30, 2021. We assessed demographic, clinical variables and the interval between the vaccination and onset of headache. We assessed whether the presence of headache was associated with higher probability of death or intracranial hemorrhage. We identified 77 cases of CVT after COVID-19 vaccination. Patients’ age was below 60 years in 74/77 (95.8%) cases and 61/68 (89.7%) were women. Headache was described in 38/77 (49.4%) cases, and in 35/38 (92.1%) was associated with other symptoms. Multiple organ thrombosis was reported in 19/77 (24.7%) cases, intracranial hemorrhage in 33/77 (42.9%) cases and 19/77 (24.7%) patients died. The median time between vaccination and CVT-related headache onset was 8 (interquartile range 7.0–9.7) days. The presence of headache was associated with a higher odd of intracranial hemorrhage (OR 7.4; 95% CI: 2.7–20.8, p < 0.001), but not with death (OR: 0.51, 95% CI: 0.18–1.47, p = 0.213). Conclusion Delayed onset of headache following an adenovirus vector-based COVID-19 vaccine is associated with development of CVT. Patients with new-onset headache, 1 week after vaccination with an adenovirus vector-based vaccine, should receive a thorough clinical evaluation and CVT must be ruled out.


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