scholarly journals Malignant histiocytosis of lungs and chest wall: A case report of diagnostic conundrum and treatment challenges in a resource-poor setting

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Jameel Ismail Ahmad ◽  
Ismail Mohammed Inuwa ◽  
Dalha Gwarzo Haliru ◽  
Imam Mohammed Ibrahim

Malignant histiocytosis is a rare condition with variable clinical presentation and prognosis. Its diagnosis requires high index of suspicion and further evaluation. Thus, it poses a diagnostic as well as management challenges especially in resource poor setting. The objective is to highlight the diagnosis and treatment challenges in the management of malignant histiocytosis so that physicians can diagnose it early and initiate appropriate treatment. Our patient is a 35-year-old man who presented with chest wall mass, dyspnoea and right cervical lymphadenopathy He was initially being evaluated for lymphoma. Biopsy of the lymph nodes was done twice in different hospitals and that of the chest wall mass done once. Histological diagnosis was arrived at with the aid of immunohistochemistry three months after his first presentation to the hospital. The patient was then commenced on chemotherapy and showed remarkable improvement on the short-term basis. Malignant histiocytosis is a rare disease laden with management challenges. Despite that, its diagnosis and treatment can be achieved even in resource poor setting with high index of suspicion, team work and good laboratory support.

2021 ◽  
Vol 64 ◽  
pp. 101725
Author(s):  
Danny Lascano ◽  
Michael J. Zobel ◽  
Abigail K. Zamora ◽  
Murad Alturkustani ◽  
Shengmei Zhou ◽  
...  

2016 ◽  
pp. bcr2016214797
Author(s):  
Ku Hung Hsieh ◽  
Grace Tan Hwei Ching ◽  
Angela Chong Phek Yoon ◽  
Melissa Teo

2019 ◽  
Vol 36 (1) ◽  
pp. 211-212
Author(s):  
Divya Ragate ◽  
Charanpreet Singh ◽  
Navneet Arora ◽  
Arihant Jain ◽  
Deepesh Lad ◽  
...  

CHEST Journal ◽  
2002 ◽  
Vol 121 (5) ◽  
pp. 1692-1694
Author(s):  
George S. Stoica ◽  
Harry N. Steinberg ◽  
Leonard J. Rossoff

Author(s):  
Jakob M Domm ◽  
Joanne M Langley

Empyema necessitans (EN) is a rare but dangerous complication of a lower respiratory tract infection. The diagnosis can be difficult to make and therefore delayed. We describe a case of a child with an atypical presentation of EN. He was afebrile and without chest pain and presented with a palpable chest wall mass after a history of recent respiratory infection. The threshold of suspicion for EN should be low, and it must be suspected in all children with a chest wall mass and recent history of respiratory infection.


2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
R Reid ◽  
F Alakhras Aljanadi ◽  
R Beattie ◽  
A Graham

Abstract Aim We aim to present here a case of a painless anterior chest wall mass which was first noted during routine follow up post coronary artery bypass graft surgery Case presentation An 80-year-old male developed an asymptomatic slow growing pronounced swelling over the right anterior chest wall post CABG. His other past medical history includes chronic obstructive pulmonary disease, pulmonary fibrosis, ischaemic heart disease, an AICD for complete heart block, hypertension, hyperlipidaemia and osteoarthritis. A CT scan demonstrated a 10 x 12 x 6.5 cm subcutaneous lesion at the mid-line of the lower chest wall adjacent to the xiphisternum and the previous sternotomy site. On clinical examination there was a large non-tender cystic swelling with peripheral calcifications, but overlying skin was normal. Fluid was aspirated from the lesion and cytology showed a paucicellular specimen with features in keeping with seroma. Due to the progressive increase in size patient underwent surgical resection. A gelatinous bloody fluid was aspirated from the lesion and it was then resected enbloc. The tumour base appeared to arise from 6/7th costal cartilage and tumour was shaved away. The mass was confirmed histologically to be chondrosarcoma. Conclusions Given the uncommon prevalence of malignant primary chest wall tumours this case highlights the importance of high clinical suspicion even after developing post CABG.


2011 ◽  
Vol 11 (1) ◽  
pp. 42-47
Author(s):  
Frederico Ferreira Souza ◽  
Mauricio De Angelo Andrade ◽  
Andrew Smith ◽  
Daniel B. Dei Santi

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