scholarly journals The role of side stream dark field microvasculature imaging in a rare case of vancomycin-resistant enterococcal endocarditis complicated by heparin-induced thrombocytopenia

2016 ◽  
Vol 19 (1) ◽  
pp. 197 ◽  
Author(s):  
Janak Bechar ◽  
Luigi Polesello ◽  
Maria Lombrano ◽  
Giampaolo Martinelli ◽  
Heyman Luckraz
Hematology ◽  
2016 ◽  
Vol 2016 (1) ◽  
pp. 262-268 ◽  
Author(s):  
Oluwatoyosi Onwuemene ◽  
Gowthami M. Arepally

Abstract Heparin-induced thrombocytopenia (HIT) remains an important diagnosis to consider in hospitalized patients developing thrombocytopenia. HIT is an immune-mediated prothrombotic disorder caused by antibodies to platelet factor 4 (PF4) and heparin. Recent basic scientific studies have advanced our understanding of disease pathogenesis through studies of the PF4/heparin structure, immune mechanisms, and cellular basis of thrombosis. Clinical advances have also occurred in areas of HIT prevention, description of disease variants, and diagnostic strategies. Emerging anticoagulants with the potential to change HIT treatment are evolving, although with limited data. This review will provide a current perspective on HIT pathogenesis, disease features, diagnostic strategies, and role of emerging therapies for the management of HIT.


2021 ◽  
Vol 36 (3) ◽  
pp. 312
Author(s):  
Tejonath Gadepalli ◽  
ZakirAli Abubacker ◽  
Pratyusha Bikkina ◽  
MadhuVijay Pasupula
Keyword(s):  
Ct Scan ◽  
Pet Ct ◽  

2021 ◽  
pp. 000313482110415
Author(s):  
James Alford Flippin ◽  
Evelyn Truong ◽  
Sami Kishawi ◽  
Annie Allan ◽  
Vanessa P. Ho

We present a rare case of traumatic self-enucleation of the bilateral globes resulting in traumatic subarachnoid and intraventricular hemorrhages. This case highlights the critical importance of multidisciplinary trauma care, starting with recognition of the potential for less obvious injuries such as contralateral optic nerve injury in unilateral enucleation, intracranial hemorrhage, and cerebrovascular injuries. We highlight the role of a thorough trauma assessment and workup, especially in the context of highly distracting injuries in patients who may also have severe mental illness. The trauma and acute care surgeon, who also serves as the critical care specialist, should be well prepared to facilitate care between multiple subspecialists including neurosurgeons, interventional radiologists, vascular surgeons, and psychiatrists, with a high index of suspicion for occult trauma in seemingly isolated injuries.


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