Formulation and in vitro characterization of alginate microspheres loaded with diloxanide furoate for colon- specific drug delivery

2010 ◽  
Vol 4 (4) ◽  
pp. 199 ◽  
Author(s):  
Deepak Jain ◽  
Kavita Verma ◽  
Sofiya Verma ◽  
Shailendra Shukla
Keyword(s):  
Drug Delivery ◽  
Specific Drug ◽  
In Vitro Characterization ◽  
Colon Specific Drug Delivery

scholarly journals Synthesis, in-vitro characterization and pharmacological evaluation of conjugates of flurbiprofen and polysaccharides for colon specific drug delivery

2019 ◽  
Vol 9 (2) ◽  
pp. 316-320
Author(s):  
P Soni ◽  
K Soni ◽  
GP Choudhary
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Specific Drug ◽  
Glycosidic Linkage ◽  
In Vitro Drug Release ◽  
In Vitro Characterization ◽  
Microbial System ◽  
Colon Specific Drug Delivery ◽  
Upper Gastrointestinal

The aim of the study was to prepare site specific drug delivery of flurbiprofen using polysaccharides by the formation of glycosidic linkage which is hydrolysed by the microflora present in colon. This approach prevents drug release in the upper gastrointestinal environment. Due to the minimal degradation of conjugates in upper Git, the in vitro drug release in SGF, SIF and SCF was found upto 4.26±0.03%, 12.41±0.08% and 92.72±3.33% respectively. Keywords: Colon specific drug delivery, Conjugates, Flurbiprofen, Microbial system.

scholarly journals SYNTHESIS AND IN VITRO BIODEGRADATION OF AZO POLYMER FOR COLON-SPECIFIC DRUG DELIVERY

2009 ◽  
Vol 007 (1) ◽  
pp. 8-14
Author(s):  
Junying LAI ◽  
Wenjing LI ◽  
Hongjun WANG ◽  
Kehua TU ◽  
Liqun WANG
Keyword(s):  
Drug Delivery ◽  
Specific Drug ◽  
Azo Polymer ◽  
Colon Specific Drug Delivery
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