scholarly journals Ethnobotanical survey of antimalarial plants in Awash-Fentale District of Afar Region of Ethiopia and in vivo evaluation of selected ones against Plasmodium berghei

2018 ◽  
Vol 8 (1) ◽  
pp. 73 ◽  
Author(s):  
Mirutse Giday ◽  
Nega Alelign ◽  
Tilahun Teklehaymanot ◽  
Abebe Animut
Keyword(s):  
Plasmodium Berghei ◽  
Ethnobotanical Survey ◽  
In Vivo Evaluation ◽  
Afar Region

scholarly journals In vivo Evaluation of Antiplasmodial Properties of Myosotis scorpioides L. (Boraginaceae) Extract in Albino Mice Infected with Plasmodium berghei

2018 ◽  
Vol 2 (4) ◽  
pp. 198-202
Author(s):  
Abdu Zakari ◽  
◽  
Sani Isyaka ◽  
Christiana Kendeson ◽  
Dimas Kubmarawa ◽  
...  
Keyword(s):  
Plasmodium Berghei ◽  
In Vivo Evaluation ◽  
Albino Mice

scholarly journals In vivo Evaluation of Anti-malarial Activity of Stem and Root Extracts of Erythrina abyssinica

2019 ◽  
pp. 1-5
Author(s):  
Daniel W. Onyango ◽  
Jacob O. Midiwo
Keyword(s):  
Survival Time ◽  
Plasmodium Berghei ◽  
Post Infection ◽  
In Vivo Evaluation ◽  
Female Mice ◽  
Root Extracts ◽  
Blood Smears ◽  
Erythrina Abyssinica ◽  
Dose Dependent

Aims: The aim of the study was to determine the in vivo anti-malarial activity of stem and root extracts of E. abyssinica using the 4-day suppressive in vivo anti-malarial test. Methodology: Female mice weighing approximately 20±2 g were intra-peritoneally injected with mice passaged Plasmodium berghei parasites. The extracts were then administered orally 2 h post-infection and, subsequently, daily for 4 days. On the 4th day, blood smears were prepared from all the mice, stained with giemsa and parasitaemia as well as chemosuppression determined. Results: Comparatively, the root extracts exhibited higher chemosuppression than stem extracts and the level of chemosuppression was dose dependent being the highest at 50 mg/kg and lowest at 12.5 mg/kg. Survival time in extract treated and chloroquine treated groups was 2 to 3 fold higher than the –ve control. Conclusion: These findings suggest that the root extracts are more efficacious in suppressing the development of full blown malaria compared to stem extracts and may be a useful candidate in managing malaria in future.

Radiolabelling and in vivo evaluation of [11C]GSK215083 as potential PET radioligand for the 5-HT6 receptor in the porcine brain

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S598-S598 ◽  
Author(s):  
Laurent Martarello ◽  
Vincent J Cunningham ◽  
Julian C Matthews ◽  
Eugenii Rabiner ◽  
Steen Jakobsen ◽  
...  
Keyword(s):  
In Vivo Evaluation ◽  
Porcine Brain

In vivo evaluation of [11C]CNS-5161 as a use-dependent ligand for the NMDA glutamate receptor channel

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S595-S595 ◽  
Author(s):  
Wynne K Schiffer ◽  
Deborah Pareto-Onghena ◽  
HaiTao Wu ◽  
Kuo-Shyan Lin ◽  
Andrew R Gibbs ◽  
...  
Keyword(s):  
Glutamate Receptor ◽  
In Vivo Evaluation ◽  
Nmda Glutamate Receptor ◽  
Receptor Channel

In vitro and in vivo evaluation of the anti-inflammatory effects of Arzanol from Helichrysum italicum

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
J Bauer ◽  
F Dehm ◽  
A Koeberle ◽  
F Pollastro ◽  
G Appendino ◽  
...  
Keyword(s):  
In Vivo Evaluation ◽  
Anti Inflammatory
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