Profile of patients having pelvic inflammatory disease and prevalence of Chlamydia trachomatis infection in the symptomatic women attending Gynecology unit in a tertiary center

Chlamydia trachomatis is an important agent of pelvic inflammatory disease (PID) globally. Laboratory diagnosis, which is vital for early and appropriate treatment, remains a challenge in resource-limited settings. Our study was undertaken to detect C. trachomatis in women with clinical features of PID. Three endocervical swabs, each obtained from 100 women clinically diagnosed with PID, were subjected to C. trachomatis antigen detection, microscopy and bacteriological culture. Logistic regression was used to assess the risk factors associated with PID. C. trachomatis antigen was present in 6%. The use of hormonal contraception, previous history of PID and a smoking habit were found to have statistically significant association in those who tested positive. Adjunctive use of rapid Chlamydia antigen test with a routinely practiced syndromic approach is beneficial for timely and appropriate antimicrobial therapy in women with PID.

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Unveiling New Molecular Factors Useful for Detection of Pelvic Inflammatory Disease due to Chlamydia trachomatis Infection

ISRN Obstetrics and Gynecology ◽

10.5402/2012/581725 ◽

2012 ◽

Vol 2012 ◽

pp. 1-7

Author(s):

Carmen Rodriguez-Cerdeira ◽

Elena Sanchez-Blanco ◽

Alberto Molares-Vila ◽

Alfonso Alba

Keyword(s):

Chlamydia Trachomatis ◽

Pelvic Inflammatory Disease ◽

Inflammatory Disease ◽

Genital Tract ◽

Nucleic Acid Amplification ◽

Chlamydia Trachomatis Infection ◽

Diagnosis And Prognosis ◽

Pubmed Database ◽

Genital Tract Infections ◽

Tract Infections

Background. Untreated Chlamydia trachomatis infections in women can result in disease sequelae such as pelvic inflammatory disease (PID), ultimately culminating in tubal occlusion and infertility. While nucleic acid amplification tests can effectively diagnose uncomplicated lower genital tract infections, they are not suitable for diagnosing upper genital tract pathological sequelae. Objective. The purpose of this paper was to provide a comprehensive review of new molecular factors associated with the diagnosis and prognosis of PID. Material and Methods. The literature was searched using the key words “Chlamydia trachomatis infections,” “pelvic inflammatory disease,” and “molecular factors” in the PubMed database. Relevant articles published between 1996 and 2012 were evaluated. Conclusions. The use of new molecular factors could potentially facilitate earlier diagnosis and prognosis in women with PID due to C. trachomatis infection.

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Impact of the Levonorgestrel-Releasing Intrauterine System on the Progression of Chlamydia trachomatis Infection to Pelvic Inflammatory Disease in a Baboon Model

The Journal of Infectious Diseases ◽

10.1093/infdis/jix545 ◽

2017 ◽

Vol 217 (4) ◽

pp. 656-666 ◽

Cited By ~ 6

Author(s):

Alison J Eastman ◽

Ingrid L Bergin ◽

Daniel Chai ◽

Christine M Bassis ◽

William LeBar ◽

...

Keyword(s):

Chlamydia Trachomatis ◽

Pelvic Inflammatory Disease ◽

Inflammatory Disease ◽

Chlamydia Trachomatis Infection ◽

Baboon Model

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Dynamic laparascopy as a stage of hospital rehabilitation in patients with tubal pregnancy

Journal of obstetrics and women s diseases ◽

10.17816/jowd87218 ◽

2005 ◽

Vol 54 (5S) ◽

pp. 33-34

Author(s):

Е. V. Shipitsyna ◽

А. V. Novikov ◽

К. V. Shalepo ◽

V. F. Bezhenar ◽

А. М. Savicheva

Keyword(s):

Chlamydia Trachomatis ◽

Ectopic Pregnancy ◽

Pelvic Inflammatory Disease ◽

Inflammatory Disease ◽

Genital Tract ◽

Tubal Pregnancy ◽

Tubal Infertility ◽

Chlamydia Trachomatis Infection ◽

Hospital Rehabilitation

Objectives: Chlamydia trachomatis infection of the upper genital tract often results in pelvic inflammatory disease (PID), and its sequels include ectopic pregnancy (EP), miscarriage and tubal infertility. This study was aimed to evaluate the rate of C. trachomatis detection as well as anti-C trachomatis antibodies in women with EP.

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