scholarly journals Reliability and interobserver variability of evans' index and disproportionately enlarged subarachnoid space hydrocephalus as diagnostic criteria for idiopathic normal pressure hydrocephalus

2020 ◽  
Vol 15 (1) ◽  
pp. 107
Author(s):  
Kiyoshi Takagi ◽  
Ryota Watahiki ◽  
Toru Machida ◽  
Kenji Onouchi ◽  
Kazuyoshi Kato ◽  
...  
Keyword(s):  
Diagnostic Criteria ◽  
Normal Pressure Hydrocephalus ◽  
Subarachnoid Space ◽  
Interobserver Variability ◽  
Normal Pressure ◽  
Idiopathic Normal Pressure Hydrocephalus ◽  
Evans Index

scholarly journals Diagnostic Performance of Glymphatic System Evaluation Using Diffusion Tensor Imaging in Idiopathic Normal Pressure Hydrocephalus and Mimickers

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Hajime Yokota ◽  
Arvind Vijayasarathi ◽  
Milos Cekic ◽  
Yoko Hirata ◽  
Michael Linetsky ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Normal Pressure Hydrocephalus ◽  
Diagnostic Performance ◽  
Roc Analysis ◽  
Diffusion Tensor ◽  
Normal Pressure ◽  
Idiopathic Normal Pressure Hydrocephalus ◽  
Glymphatic System ◽  
Evans Index ◽  
Diffusion Tensor Imaging Dti

Purpose. To investigate the pathological change of the glymphatic system in idiopathic normal pressure hydrocephalus (iNPH) using diffusion tensor imaging (DTI) analysis. Materials and Methods. 24 right-handed patients were referred to our hydrocephalus clinic for assessment of ventriculomegaly and gait impairment. 12 of 24 were diagnosed as pseudo-iNPH (piNPH) based on assessment by a neurologist. Diffusivity maps in the direction of the x-axis (right-to-left) (Dx), y-axis (anterior-to-posterior) (Dy), and z-axis (inferior-to-superior) (Dz) were computed. The diffusion map was coregistered to International Consortium for Brain Mapping (ICBM) DTI-81 atlas. The analysis along the perivascular space (ALPS) index was defined as mean (Dxpro, Dypro)/mean (Dypro, Dzasc), where Dxpro and Dxasc are Dx values in the projection and association fiber areas, respectively. Evans index and callosal angle were also assessed on each case. Results. ALPS indexes of the control, piNPH, and iNPH cases were 1.18 ± 0.08, 1.08 ± 0.03, and 0.94 ± 0.06, respectively, and there were significant differences among the groups (control vs. piNPH, P = 0.003; control vs. iNPH P < 0.001; piNPH vs. iNPH, P < 0.001). Area under curve (AUC) was 0.92, 1.00, and 1.00 on control vs. piNPH, control vs. iNPH, and piNPH vs. iNPH on ROC analysis. Between piNPH and NPH, ALPS index has higher diagnostic performance than Evans index and callosal angle (AUC = 1.00 vs. 0.84, P = 0.028; AUC = 1.00 vs. 0.74, P = 0.016). Conclusion. Atlas-based ALPS index using the DTI method differentiated among iNPH, piNPH, and controls clearly.

scholarly journals Parkinsonian Symptomatology May Correlate with CT Findings before and after Shunting in Idiopathic Normal Pressure Hydrocephalus

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Mitsuaki Ishii ◽  
Toshio Kawamata ◽  
Ichiro Akiguchi ◽  
Hideo Yagi ◽  
Yuko Watanabe ◽  
...  
Keyword(s):  
Normal Pressure Hydrocephalus ◽  
Postural Stability ◽  
Rating Scale ◽  
Normal Pressure ◽  
Idiopathic Normal Pressure Hydrocephalus ◽  
Stepwise Multiple Regression ◽  
Ct Findings ◽  
Before And After ◽  
Evans Index ◽  
Disease Rating

We aimed to investigate the characteristics of Parkinsonian features assessed by the unified Parkinson's disease rating scale (UPDRS) and determine their correlations with the computed tomography (CT) findings in patients with idiopathic normal pressure hydrocephalus (iNPH). The total score and the scores for arising from chair, gait, postural stability, and body hypokinesia in the motor examination section of UPDRS were significantly improved after shunt operations. Stepwise multiple regression analysis revealed that postural stability was the determinant of the gait domain score of the iNPH grading scale. The canonical correlation analysis between the CT findings and the shunt-responsive Parkinsonian features indicated that Evans index rather than midbrain diameters had a large influence on the postural stability. Thus, the pathophysiology of postural instability as a cardinal feature of gait disturbance may be associated with impaired frontal projections close to the frontal horns of the lateral ventricles in the iNPH patients.

scholarly journals Changes in the Subarachnoid Space Precede Ventriculomegaly in Idiopathic Normal Pressure Hydrocephalus (iNPH)

2012 ◽  
Vol 51 (13) ◽  
pp. 1751-1753 ◽  
Author(s):  
Chifumi Iseki ◽  
Yoshimi Takahashi ◽  
Manabu Wada ◽  
Shigeki Arawaka ◽  
Toru Kawanami ◽  
...  
Keyword(s):  
Normal Pressure Hydrocephalus ◽  
Subarachnoid Space ◽  
Normal Pressure ◽  
Idiopathic Normal Pressure Hydrocephalus

WP1-10 Prevalence of normal pressure hydrocephalus in falls clinic patients

2019 ◽  
Vol 90 (3) ◽  
pp. e4.2-e4 ◽  
Author(s):  
S Sennik ◽  
C Craven ◽  
L D’Antona ◽  
H Asif ◽  
W Dawes ◽  
...  
Keyword(s):  
General Hospital ◽  
Normal Pressure Hydrocephalus ◽  
Normal Population ◽  
District General Hospital ◽  
Normal Pressure ◽  
Idiopathic Normal Pressure Hydrocephalus ◽  
List Type ◽  
Ventricular Enlargement ◽  
Evans Index ◽  
One Year

ObjectivesPatients with idiopathic Normal Pressure Hydrocephalus (iNPH) present with Hakim Adams triad and radiological findings suggestive of iNPH. We compare the presence of clinical and radiological signs of iNPH present in patients presenting to falls clinic at a District General Hospital with the general population.DesignRetrospective analysis of patients referred to falls clinic (January 2017 to December 2017) and interpretation of CT or MRI head imaging with Evans index.SubjectsFalls clinic patients presenting to a District General Hospital outpatient clinic.MethodsRetrospective cohort of patients admitted to a single District General Hospital with falls and recent CT or MRI head. An Evans Index above 0.35 was used as an indicator of hydrocephalic ventricular enlargement.Results371 patients were seen in one year. 216 had previous CT or MRI head. 6.75% of all patients seen in falls clinic (11.6% who have had brain imaging) have hydrocephalic ventricular enlargement. This is compared to 4.5% in a study of patients aged 70 and over in a normal population.1ConclusionsPatients seen in Falls clinic have an increased probability of having radiological signs consistent with idiopathic normal pressure hydrocephalus.ReferenceJaraj D, Marlow T, Jensen C, Skoog I, Wikkelso C. Prevalence of idiopathic normal-pressure hydrocephalus. Neurology2014April 22;82(16):1449–1454.

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