scholarly journals A preliminary exploration of acute intracranial pressure-cerebrospinal fluid production relationships in experimental hydrocephalus

2020 ◽  
Vol 6 (3) ◽  
pp. 200
Author(s):  
AhmadH Khasawneh ◽  
PetrojC Alexandra ◽  
PaulA Zajciw ◽  
CarolynA Harris
Author(s):  
Alexander Gamble ◽  
Harold Rekate

Hydrocephalus is a condition characterized by a dynamic imbalance between the formation (production) and absorption of spinal fluid resulting in an increase in the size of the ventricular spaces. New techniques used to study the chemistry and physics of cerebrospinal fluid production, flow and absorption have led to new insights into the pathophysiology of hydrocephalus and other abnormalities of cerebrospinal fluid (CSF) dynamics. The importance of research into the role of aquaporins, other channel types and absorption of CSF into the systemic circulation via the lymphatics and intraparenchymal veins opens alternative explanations for enigmatic disorders of CSF. A contemporary classification of hydrocephalus based on the point of restriction of CSF flow has been shown to explain all problems related to clinical disorders of CSF and intracranial pressure. The distinct differences between hydrocephalus which develops in babies with growing heads and those that become symptomatic later in life.


2004 ◽  
Vol 19 (1) ◽  
pp. 76-78 ◽  
Author(s):  
Kotaro Oshio ◽  
Hiroyuki Watanabe ◽  
Yaunlin Song ◽  
A. S. Verkman ◽  
Geoffrey T. Manley

2020 ◽  
Vol 31 (11) ◽  
pp. 1117-1119
Author(s):  
Sharon Chi ◽  
Amy Weintrob

Idiopathic intracranial hypertension (IIH), or pseudotumor cerebri, is a diagnosis of exclusion. Elevated intracranial pressure (ICP) can result from a variety of inflammatory and structural causes affecting cerebrospinal fluid production and absorption. First described in 1935, syphilis is a well-established cause of elevated ICP, referred to as syphilitic hydrocephalus. We report a case of a 49-year-old man presenting with vision changes and headache who was treated for IIH without resolution of symptoms, and eventually diagnosed with syphilitic hydrocephalus. Syphilis should be considered as a cause of elevated ICP prior to a diagnosis of IIH.


2017 ◽  
Author(s):  
Hannah Botfield ◽  
Maria Uldall ◽  
Connar Westgate ◽  
James Mitchell ◽  
Snorre Hagen ◽  
...  

Author(s):  
Joanna M. Wardlaw ◽  
Helene Benveniste ◽  
Maiken Nedergaard ◽  
Berislav V. Zlokovic ◽  
Serge Charpak ◽  
...  

2021 ◽  
Vol 3 (3) ◽  
Author(s):  
Marcos Vilca ◽  
◽  
Carlos Palacios ◽  
Sofía Rosas ◽  
Ermitaño Bautista ◽  
...  

Introduction: Pneumocephalus is mainly associated with traumatic injuries, being a rare complication but with high mortality rates; it behaves like a space-occupying lesion and increases intracranial pressure. The symptoms are not specific, but in the event of trauma it is necessary to suspect this entity to carry out a timely diagnosis and treatment, since being the product of the skull base fracture it can cause communication with the outside, and the appearance of cerebrospinal fluid (CSF) leak. Clinical Case: a 38-year-old male patient who suffers trauma from a pyrotechnic explosion near his right ear, when handling a pyrotechnic object (whistle) during the New Year, presenting severe pain, slight bleeding in the right ear, feeling faint and holocranial headache that increased in a standing position; likewise, he presents high-flow aqueous secretion (CSF) from the right ear. Brain and skull base tomography (CT) showed air in the intracranial cavity, fracture of the skull base, and the ossicles of the right middle ear. Conservative management was performed using rest and lumbar drainage, presenting a satisfactory evolution. Conclusion: Pneumocephalus is a frequent and expected complication of trauma with a skull base fracture. Its early and timely diagnosis using skull base CT is essential to define therapeutic measures. Accidents due to the misuse of pyrotechnics continue to be a relevant problem in our country. Knowing and disseminating its consequences can help raise awareness in the population. Keywords: Pneumocephalus, Skull Base, Intracranial Pressure, Cerebrospinal Fluid Leak. (Source: MeSH NLM)


Sign in / Sign up

Export Citation Format

Share Document