scholarly journals Neutrophil-to-lymphocyte ratio: relation to disease activity and carotid intima-media thickness in Behçet’s disease

2018 ◽  
Vol 45 (4) ◽  
pp. 133
Author(s):  
RashaM Fawzy ◽  
MounirSerag Elden ◽  
Gamal Hmmad ◽  
Hesham Farouk ◽  
Basma Abdelwhaba
Keyword(s):  
Disease Activity ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Neutrophil To Lymphocyte Ratio ◽  
Behcet's Disease ◽  
Lymphocyte Ratio ◽  
Media Thickness

Investigation of the arterial intima-media thickness in Behcet’s disease patients without vascular complaints

Vascular ◽  
2017 ◽  
Vol 26 (4) ◽  
pp. 356-361
Author(s):  
Nazım Kankilic ◽  
Aydın Aslan ◽  
Oguz Karahan ◽  
Sinan Demirtas ◽  
Ahmet Caliskan ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Intima Media Thickness ◽  
Vascular Involvement ◽  
Behcet's Disease ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Media Thickness ◽  
Arterial Intima

Objectives Behcet’s disease is a multisystemic, inflammatory disease. Various factors have been implicated in the disease, including genetics, infections, immunoglobulins, immune complexes, antibodies, and oxidative stress. However, the underlying etiopathogenesis remains unclear. Behcet’s disease can occur with or without vascular involvement. This prospective study investigated the relationship between the intima-media thickness of the major arteries, in addition to other factors affecting the disease process, in Behcet’s disease without vascular involvement. Methods Twenty-four patients (average age: 38.50 ± 10.931) without vascular involvement or any vascular complaints who were diagnosed with Behcet’s disease were included in the study. Sixteen healthy subjects (average age: 39.75 ± 7.793) were included as a control group. Demographic information and medical histories were recorded, and routine blood tests were performed in both groups. The intima-media thickness of the subclavian, axillary, femoral, and carotid arteries of all the participants were recorded using Doppler ultrasonography. The data were then subjected to intergroup statistical and correlation analyses. Results There were no significant differences between the arterial intima-media thickness values of the Behcet’s disease patients and those of the control group ( p > 0.05). However, there was a significant difference between the neutrophil–lymphocyte ratio ( p = 0.004), low-density lipoprotein ( p = 0.007), and triglyceride ( p = 0042) levels of the two groups. Significant correlations were found between intima-media thickness and neutrophil–lymphocyte ratio levels ( p = 0.012) and the disease duration ( p = 0.030). There was also a significant correlation between the intima-media thickness of the femoral artery and disease duration ( p = 0.014). Conclusions The results showed that the duration of illness had a significant effect on arterial intima-media thickness in Behcet’s disease. Blood neutrophil–lymphocyte ratio levels were also associated with increased intima-media thickness.

Intima-Media Thickness and Arterial Distensibility in Behçet’s Disease

Angiology ◽  
2004 ◽  
Vol 55 (4) ◽  
pp. 413-419 ◽  
Author(s):  
Sait Alan ◽  
Mehmet S. Ulgen ◽  
Sedat Akdeniz ◽  
Bircan Alan ◽  
Nizamettin Toprak
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Intima Media Thickness ◽  
Arterial Distensibility ◽  
Behcet's Disease ◽  
Media Thickness

Correlation of Clinical Signs and Symptoms of Behçet’s Disease With Platelet to Lymphocyte Ratio (PLR) and Neutrophil to Lymphocyte Ratio (NLR)

2021 ◽  
Author(s):  
Soraya Shadmanfar ◽  
Maryam Masoumi ◽  
Fereydoun Davatchi ◽  
Farhad Shahram ◽  
Maassoumeh Akhlaghi ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Neutrophil To Lymphocyte Ratio ◽  
P Value ◽  
Platelet To Lymphocyte Ratio ◽  
Behcet's Disease ◽  
Lymphocyte Ratio ◽  
Spearman's Rho ◽  
Spearman’S Rho

Abstract BackgroundBehçet’s disease (BD) is a chronic disorder that involves multiple organs and is pathologically considered as a form of vasculitis. The current study aims to assess the metric properties of platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) in assessing BD disease activity.MethodsThree-hundred-nineteen patients with BD were enrolled in this cross-sectional study. Demographic and epidemiological data, including IBDDAM, time since the onset, and medication and manifestation history was recorded. Complete blood counts (CBC), NLR, and PLR were assessed by analyzing blood samples. On the last visit, patients were assessed for active manifestations of disease. IBDDAM and ocular IBDAAM scores were calculated for activity of disease in each patient.ResultsBoth PLR and NLR were higher in patients with active BD (Man-Whitney U test, P-value<0.05). Patients with active ocular manifestation had significantly higher NLR and PLR (Man-Whitney U test, P-value<0.05). These ratios, however, were not associated with other active BD manifestations. A value of NLR >2.58 had 46% sensitivity and 85% specificity for the diagnosis of active ocular manifestations (AUC: 0.690). NLR had a significant though weak positive correlation with IBDDAM (Spearman’s rho = 0.162; p-value <0.05) and ocular IBDDAM (Spearman’s rho = 0.159; p-value < 0.05). ConclusionActive Behçet’s presented with higher NLR and PLR ratios; however, there was only a modest correlation between NLR and BD activity (IBDDAM score). Also NLR and PLR have significant relationship with ocular features of BD patients.

Intima-media Thickness of Carotid Artery in Patients with Behçet’s Disease

2011 ◽  
Vol 42 (5) ◽  
pp. 398-404 ◽  
Author(s):  
Meriam Messedi ◽  
Makram Frigui ◽  
Khaireddine Ben Mahfoudh ◽  
Hanen Feki ◽  
Salma Triki Ben Mahfoudh ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Intima Media Thickness ◽  
Behcet's Disease ◽  
Media Thickness
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