scholarly journals Is immediate adjuvant radiotherapy necessary for men with positive surgical margin after robotic-assisted radical prostatectomy?

2021 ◽  
Vol 54 (6) ◽  
pp. 213
Author(s):  
Chung-Yi Liu ◽  
Yu-Ting Chen ◽  
Shih-Huan Su ◽  
Kai-Jie Yu ◽  
Ying-Hsu Chang ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Adjuvant Radiotherapy ◽  
Surgical Margin ◽  
Positive Surgical Margin ◽  
Robotic Assisted ◽  
Robotic Assisted Radical Prostatectomy

C152 Removing the specimen with traction during robotic assisted radical prostatectomy does not cause positive surgical margin

2013 ◽  
Vol 12 (4) ◽  
pp. e1260, C152a-e1260, C152b
Author(s):  
S. Altinova ◽  
E. Isgoren ◽  
Z. Akbulut ◽  
M.F. Ozcan ◽  
A.E. Canda ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Surgical Margin ◽  
Positive Surgical Margin ◽  
Robotic Assisted ◽  
Robotic Assisted Radical Prostatectomy

scholarly journals Intrafascial Dissection Significantly Increases Positive Surgical Margin and Biochemical Recurrence Rates after Robotic-Assisted Radical Prostatectomy

2012 ◽  
Vol 89 (1) ◽  
pp. 17-24 ◽  
Author(s):  
Ashkan Mortezavi ◽  
Thomas Hermanns ◽  
Hans-Helge Seifert ◽  
Peter J. Wild ◽  
Daniel M. Schmid ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Biochemical Recurrence ◽  
Surgical Margin ◽  
Positive Surgical Margin ◽  
Recurrence Rates ◽  
Robotic Assisted ◽  
Robotic Assisted Radical Prostatectomy

Clinical predictors for biochemical failure in patients with positive surgical margin after robotic-assisted radical prostatectomy

2021 ◽  
pp. 030089162110079
Author(s):  
Shih-Huan Su ◽  
Ying-Hsu Chang ◽  
Liang-Kang Huang ◽  
Yuan-Cheng Chu ◽  
Hung-Cheng Kan ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Cox Regression ◽  
Specific Antigen ◽  
Surgical Margin ◽  
Biochemical Failure ◽  
Positive Surgical Margin ◽  
Cox Regression Analysis ◽  
Robotic Assisted ◽  
Robotic Assisted Radical Prostatectomy

Objective: Patients with positive surgical margins (PSMs) after radical prostatectomy for localized prostate cancer have a higher risk of biochemical failure (BCF). We investigated the risk factors of BCF in patients with PSMs after robotic-assisted radical prostatectomy (RARP). Methods: We evaluated 462 patients who underwent RARP in a single medical center from 2006 through 2013. Of them, 61 with PSMs did not receive any treatment before BCF. Kaplan-Meier curve and Cox regression analysis were used to compare patients with (n = 19) and without (n = 41) BCF. Results: Overall, 13.2% of patients had PSMs, and of those, 31.7% experienced BCF during follow-up. The mean follow-up duration was 43.7 months (42.4 [non-BCF] vs 46.35 (BCF], p = 0.51). In univariant analyses, the platelet to lymphocyte ratio (6.26 [non-BCF] vs 8.02 [BCF], p = 0.04) differed statistically. When patients were grouped by pathologic grade ≦2 or ≧3 ( p = 0.004), the BCF-free survival rates differed significantly. Seminal vesicle invasion also differed significantly (5 [non-BCF] vs 7 [BCF], p = 0.005). Patients with undetectable nadir prostate-specific antigen (PSA) after RARP (BCF rate 4/34) differed statistically from those with detectable PSA after RARP (BCF rate 15/26) ( p < 0.001). In the multivariate analysis, the platelet/lymphocyte (P/L) ratio, pathologic grade, and undetectable nadir PSA remained statistically significant. Conclusions: In patients who undergo RARP and have PSMs, P/L ratio >9 preoperatively, pathologic grade ⩾3, and detectable nadir PSA after RARP should be considered adverse features. Early intervention such as salvage radiation therapy or androgen deprivation therapy should be offered to these patients.

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