Dermoscopy of “lichenoid pseudovesicular papular eruption on nose”

Scabies is an extremely contagious disorder caused by an itch mite, Sarcoptes scabiei, which attacks infants and children as well as adults. Infestation begins with a newly fertilized female mite. She tunnels into the stratum corneum and lives in cutaneous burrows which may measure several millimeters to a few centimeters in length. The parasite favors areas with a low concentration of pilosebaceous follicles and a thin stratum corneum. This seems to account for a difference in the distribution of lesions in infants and young children compared to older children and adults.1 INCIDENCE Epidemics of scabies occur in 30-year cycles, each one lasting about 15 years. We presently are near the end of a world-wide pandemic which began in 1964 and, if estimates are correct, should last until or beyond 1979 or 1980.2 CASE HISTOR A 3-month-old white female infant started with a pruritic eruption at 2 months of age. She had a scaly erythematous papular eruption on the trunk, the postauricular areas, and extremities (Fig 1) and was otherwise healthy.3 Microscopic examinations of skin scrapings and fungal cultures were performed, and the eruption was treated as a seborrheic dermatitis with frequent shampoos and topical fluocinolone acetonide cream. Two weeks later the rash had spread to the back of the head and neck, the entire trunk, and all extremities including the palms and soles.

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RABBIT POX

Journal of Experimental Medicine ◽

10.1084/jem.62.3.331 ◽

1935 ◽

Vol 62 (3) ◽

pp. 331-347 ◽

Cited By ~ 14

Author(s):

Paul D. Rosahn ◽

Ch'uan-K'uei Hu

Keyword(s):

Clinical Manifestations ◽

Nasal Discharge ◽

Vesicle Formation ◽

Definite Diagnosis ◽

Pathological Findings ◽

Papular Eruption ◽

Mucous Membranes ◽

Etiological Agents ◽

Microscopic Pathology ◽

Local Necrosis

Observations on an epidemic of rabbit pox occurring in an isolated animal room during the winter of 1933–34 are reported. The clinical manifestations, consisting of a generalized papular eruption involving the skin and mucous membranes, together with blepharitis, ophthalmia, nasal discharge and lymphadenopathy were essentially similar to those noted in a pox epidemic of the previous year. This was true in general also of the pathological findings except that vacuolization, local necrosis and vesicle formation were seen in the epidermis, while in the previous year the microscopic pathology in the skin was confined to the corium. Evidence was presented indicating that the infection can be transmitted through the medium of a personal carrier, and that transmission in this manner can occur during the incubation period or before a definite diagnosis is possible. The findings also demonstrated that the etiological agents responsible for the disease reported here and that of the previous year were immunologically related, and that the immunity in recovered animals effectively persisted during the entire period for which data are available, 9 to 12 months. It appeared also that young animals suckling an immune doe were more refractory to the development of the lesions of rabbit pox than were the young of susceptible does.

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