scholarly journals Unmet needs of corneal collagen cross-linking

2021 ◽  
Vol 53 (2) ◽  
pp. 173
Author(s):  
Tapasya Singha
Keyword(s):  
Unmet Needs ◽  
Cross Linking ◽  
Collagen Cross Linking ◽  
Corneal Collagen

Long term results of accelerated corneal collagen cross-linking in pediatric keratoconus

2021 ◽  
pp. 112067212110183
Author(s):  
Yasin Cinar ◽  
Cagla Cilem Han ◽  
Alparslan Sahin ◽  
Zeba A Syed
Keyword(s):  
Visual Acuity ◽  
Corneal Thickness ◽  
University Hospital ◽  
Long Term Results ◽  
Cross Linking ◽  
Distance Visual Acuity ◽  
The Mean ◽  
Collagen Cross Linking ◽  
Corneal Collagen

Purpose: To evaluate the long term visual, refractive, and corneal tomographic outcomes of epithelium-off accelerated corneal collagen cross-linking (ACXL) in the management of pediatric keratoconus (KC). Methods: This retrospective study included patients under 18 years old with progressive KC who underwent ACXL between 2012 and 2019 at Dicle University Hospital. Complete ophthalmic examination was performed including uncorrected distance visual acuity (UDVA), best spectacle-corrected distance visual acuity (CDVA), manifest refraction, and corneal tomography. Evaluations were performed preoperatively and at 6 months intervals postoperatively. Results: Forty-nine eyes of 49 patients were included in the study. The mean age of patients at the time of ACXL was 14.2 ± 1.8 (range: 9.5–17.3) years. Mean follow up was 4.61 ± 1.90 (range: 2.0–8.1) years. The mean LogMAR UDVA improved from 0.94 ± 0.41 to 0.81 ± 0.43, 0.69 ± 0.41, and 0.67 ± 0.33 after 1, 3, and 5 years respectively ( p = 0.001). The mean LogMAR CDVA improved from 0.58 ± 0.36 to 0.46 ± 0.31, 0.34 ± 0.23, and 0.39 ± 0.27 after 1, 3, and 5 years respectively ( p = 0.015). The mean refractive cylinder improved significantly from 6.01 ± 2.07 diopters (D) to 5.46 ± 1.87, 5.38 ± 2.18, and 5.02 ± 2.31 D after 1, 3, and 5 years respectively ( p = 0.005). As compared to preoperative values, steep keratometry and maximum keratometry were not significantly different ( p = 0.805 and 0.448, respectively) following ACXL, while flat keratometry significantly improved after ACXL ( p = 0.012). Although central corneal thicknesses decreased significantly ( p = 0.029), the decrease in thinnest corneal thickness was not statistically significant ( p = 0.205). Conclusion: Epithelium-off ACXL seems to be effective for halting KC progression with long term clinical benefits in pediatric patients.

Corneal Collagen Cross-Linking in Young Patients for Progressive Keratoconus

Cornea ◽  
2020 ◽  
Vol 39 (2) ◽  
pp. 186-191
Author(s):  
Paulo Rodolfo Tagliari Barbisan ◽  
Roberto Damian Pacheco Pinto ◽  
Camillo Carneiro Gusmão ◽  
Rosane Silvestre de Castro ◽  
Carlos Eduardo Leite Arieta
Keyword(s):  
Young Patients ◽  
Cross Linking ◽  
Collagen Cross Linking ◽  
Corneal Collagen

Evaluation of Subbasal Nerve Morphology and Corneal Sensation after Accelerated Corneal Collagen Cross-linking Treatment on Keratoconus

2014 ◽  
Vol 40 (5) ◽  
pp. 484-489 ◽  
Author(s):  
Engin Bilge Ozgurhan ◽  
Ugur Celik ◽  
Ercument Bozkurt ◽  
Ahmet Demirok
Keyword(s):  
Cross Linking ◽  
Corneal Sensation ◽  
Collagen Cross Linking ◽  
Corneal Collagen

Combined Transepithelial Phototherapeutic Keratectomy and Corneal Collagen Cross-Linking for Progressive Keratoconus

Ophthalmology ◽  
2012 ◽  
Vol 119 (9) ◽  
pp. 1777-1784 ◽  
Author(s):  
George D. Kymionis ◽  
Michael A. Grentzelos ◽  
George A. Kounis ◽  
Vasilios F. Diakonis ◽  
Aliki N. Limnopoulou ◽  
...  
Keyword(s):  
Cross Linking ◽  
Phototherapeutic Keratectomy ◽  
Collagen Cross Linking ◽  
Corneal Collagen
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