Oral submucous fibrosis: A case report and contemporary review of pathogenesis

2021 ◽  
Vol 12 (2) ◽  
pp. 108
Author(s):  
V Vasanthi ◽  
KB Vinitha ◽  
Diana Alexander ◽  
VM Shobika ◽  
HWahida Parveen ◽  
...  
Keyword(s):  
Case Report ◽  
Oral Submucous Fibrosis ◽  
Submucous Fibrosis

scholarly journals A 11-year-old boy with oral submucous fibrosis: A rare case report

2014 ◽  
Vol 4 (4) ◽  
pp. 511 ◽  
Author(s):  
Abhinav Srivastava ◽  
Chander Mohan ◽  
Mukta Pagrani ◽  
Shivesh Kumar
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Oral Submucous Fibrosis ◽  
Rare Case Report ◽  
Submucous Fibrosis

scholarly journals Immunohistochemical Analysis of Myofibroblasts Using α- SMA in Oral Submucous Fibrosis Turning into Malignancy- A Case Report and Review

2021 ◽  
pp. 192-198
Author(s):  
Swapan Kumar Purkait ◽  
. Abhinandan ◽  
Nimisha Priya ◽  
Sriyanshi Singh ◽  
Sneha Singh
Keyword(s):  
Case Report ◽  
Immunohistochemical Study ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Immunohistochemical Analysis ◽  
Invasive Front ◽  
Premalignant Condition ◽  
Submucous Fibrosis ◽  
Very High ◽  
Premalignant Conditions

Oral submucous fibrosis is a premalignant condition, characterized by fibrosis in oral mucosa causing stiffness of mucosa and leading to reduced mouth opening. The malignant transformation of oral submucous fibrosis is very high among the rest of the premalignant conditions. Chronic chewing of arecanut causes production of myofibroblasts. These myofibroblasts plays an important role in neoangiogenesis as well as disintegration of the basement membrane at the tumor invasive front leading to carcinoma.  Here, we are doing an Immunohistochemical study using alpha SMA for proper microscopic visulizations of myofibroblastic activity in an OSF patient, encompassing the pathogenesis and malignant potentiality of the disease.

scholarly journals Quality of Life in Oral Submucous Fibrosis- A Case Report with a Literature Review

2021 ◽  
Vol 15 (1) ◽  
pp. 4-10
Author(s):  
Shishir Ram Shetty ◽  
Sesha Reddy ◽  
Pooja Narain Adtani ◽  
Raghavendra Shetty ◽  
Ashwin Lakshminarayanan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Oral Submucous Fibrosis ◽  
Mouth Opening ◽  
Specific Questionnaire ◽  
Spicy Food ◽  
Potentially Malignant ◽  
Submucous Fibrosis ◽  
Published Research

Introduction: Oral Submucous Fibrosis (OSMF) is a potentially malignant disorder commonly found in the Southeast Asian region, classically characterized through restricted mouth opening and burning sensation in the mouth on consuming spicy food. The etiopathogenesis and treatment aspects of OSMF have been extensively researched and reviewed. However, the effect of this condition on the Quality of Life (QoL) of patients has not gained much consideration. The aim of our case report is to highlight the importance of evaluating the QoL in an OSMF patient by using discipline-specific questionnaire and also to present to the readers a review of the recently published research articles on the application of QoL questionnaires in OSMF patients. Results: It was observed that most of the researchers used generic and discipline-specific questionnaire for evaluating the quality of life in OSMF patients. Conclusion: Evaluation of QoL is recommended during the treatment of OSMF patients. There is a need to develop and employ more of disease-specific QoL instruments for OSMF patients.

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