Predicting Future Events from Longitudinal Data with Multivariate Hierarchical Models and Bayes' Theorem Using SAS

Author(s):  
Larry J. Brant ◽  
Shan L. Sheng
2021 ◽  
pp. 427-480
Author(s):  
Gary L. Rosner ◽  
Purushottam W. Laud ◽  
Wesley O. Johnson

1995 ◽  
Vol 20 (2) ◽  
pp. 205-209 ◽  
Author(s):  
Nicholas T. Longford

The view is presented that multilevel methods are just one element in a hypothetical complete analysis of observational data on human subjects. In most contexts several sources of uncertainty, in addition to those captured by a multilevel analysis, are present, and so the confidence placed in the results of a typical multilevel analysis is unrealistically optimistic. A “soft-ware-free” analysis of longitudinal data with rectangular design is outlined. Questions posed by the National Center for Education Statistics and elaborated by de Leeuw and Kreft are briefly discussed.


Symmetry ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 586
Author(s):  
Stephen M. Barnett ◽  
John Jeffers ◽  
David T. Pegg

Prediction is the making of statements, usually probabilistic, about future events based on current information. Retrodiction is the making of statements about past events based on current information. We present the foundations of quantum retrodiction and highlight its intimate connection with the Bayesian interpretation of probability. The close link with Bayesian methods enables us to explore controversies and misunderstandings about retrodiction that have appeared in the literature. To be clear, quantum retrodiction is universally applicable and draws its validity directly from conventional predictive quantum theory coupled with Bayes’ theorem.


2019 ◽  
Vol 62 (3) ◽  
pp. 577-586 ◽  
Author(s):  
Garnett P. McMillan ◽  
John B. Cannon

Purpose This article presents a basic exploration of Bayesian inference to inform researchers unfamiliar to this type of analysis of the many advantages this readily available approach provides. Method First, we demonstrate the development of Bayes' theorem, the cornerstone of Bayesian statistics, into an iterative process of updating priors. Working with a few assumptions, including normalcy and conjugacy of prior distribution, we express how one would calculate the posterior distribution using the prior distribution and the likelihood of the parameter. Next, we move to an example in auditory research by considering the effect of sound therapy for reducing the perceived loudness of tinnitus. In this case, as well as most real-world settings, we turn to Markov chain simulations because the assumptions allowing for easy calculations no longer hold. Using Markov chain Monte Carlo methods, we can illustrate several analysis solutions given by a straightforward Bayesian approach. Conclusion Bayesian methods are widely applicable and can help scientists overcome analysis problems, including how to include existing information, run interim analysis, achieve consensus through measurement, and, most importantly, interpret results correctly. Supplemental Material https://doi.org/10.23641/asha.7822592


2015 ◽  
Vol 72 (2) ◽  
pp. 93-98
Author(s):  
Andreas R. Huber
Keyword(s):  

Biochemische Erkenntnisse und das Wissen über Stoffwechselvorgänge bis zum einzelnen Molekül und die rasche Entwicklung von neuen, sehr leistungsfähigen Methoden haben es erlaubt, dass die Labormedizin als wichtiger Bestandteil von Diagnose, Ausschluss, Therapie, Monitoring und als prädiktiver Test Einzug in die Medizin erhalten hat. Wichtig ist nicht nur die Qualität des Assays, sondern auch das Fachwissen um den Test, d. h. dass ein Test für die richtige Fragestellung eingesetzt wird und die Wertigkeit dem Kliniker bekannt ist. Hinzu kommen das Einhalten der präanalytischen Bedingungen, Kenntnisse über statistische Fakten wie Bayes Theorem und der gekonnte Miteinbezug anderer Resultate, klinischer Gegebenheiten. So lässt sich Berechnung oder wenigstens Abschätzung einer postanalytischen Wahrscheinlichkeit erheben. Der gleiche Test wird eine sehr unterschiedliche Performance haben je nach dem gewählten Einsatzort, resp. dem gewählten Patientenkollektiv. So macht z. B. ein erstmaliger PSA-Test bei einem 70-jährigen Patienten wenig Sinn. Weiter spielen auch die Qualitäten des Tests eine entscheidende Rolle. Es kann davon ausgegangen werden, dass gerade in der Labormedizin weitere Outcome-Studien folgen werden. Der Wert dieser nimmt zu, da die Tests in der Regel nicht bis wenig invasiv, relativ günstig und rasch erhältlich sind.


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