scholarly journals Cytomorphological Aspects of Hashimoto's Thyroiditis: Our Experience at a Tertiary Center

2014 ◽  
Vol 7 ◽  
pp. CPath.S13580 ◽  
Author(s):  
Monika Rathi ◽  
Faiyaz Ahmad ◽  
Satish Kumar Budania ◽  
Seema Awasthi ◽  
Ashutosh Kumar ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Hashimoto’S Thyroiditis ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Hashimoto's Thyroiditis ◽  
Thyroid Function Tests ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Tertiary Center ◽  
Needle Aspiration Cytology

Introduction Hashimoto's thyroiditis is the most common form of acquired hypothyroidism. Fine needle aspiration cytology is one important tool in diagnosing Hashimoto's thyroditis, along with clinical, biochemical, immunological and ultrasonographical modalities. The present study examines cytological aspects of Hashimoto's thyroiditis along with their correlation with clinical, biochemical and immunological findings, whenever available. Materials and Methods This is a retrospective study of 50 cases of Hashimoto's thyroiditis. Cytological findings were reviewed and correlated with clinical, biochemical and immunological findings whenever available. Results The majority of the patients were middle-aged females, with a female to male ratio of 6.14:1. Most patients presented with diffuse thyromegaly (68%) and/or hypothyroidism (56.09%). The antibody profile was available in 22% of patients. Of these, anti-thyroid peroxidase antibodies were raised in 81.81% of patients and anti-thyroglobulin antibodies were raised in 63.63% of patients. In the present study, high lymphoid to epithelial cell ratio was seen in 78% of cases, and 74% of cases showed Hurthle cell change. Follicular atypia was seen in 36% of cases. Lymphoid follicle formation was seen in seen in 54% of cases. Follicular cell infiltration by lymphocytes, eosinophils and neutrophils was seen in 72%, 48% and 26% of cases, respectively. Plasma cells were seen in 18% of cases. Conclusion Thyroid function tests and immunological tests cannot diagnose all cases of Hashimoto's thyroiditis. Fine needle aspiration cytology continues to be a diagnostic tool of significance in diagnosing Hashimoto's thyroiditis. The presence of inflammatory cells, particularly lymphocytes and eosinophils, was detected in a significant proportion of cases.

scholarly journals Evaluation of Different Thyroid Lesions with Fine Needle Aspiration Cytology and Thyroid Function Tests

2018 ◽  
Vol 11 (1) ◽  
pp. 17-22
Author(s):  
S Ranabhat ◽  
B Parajuli ◽  
S Poudel ◽  
G Pun
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Age Groups ◽  
Needle Aspiration ◽  
Thyroid Function Tests ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Hormonal Analysis ◽  
Thyroid Lesions

Introduction: Swelling of the thyroid gland is a commonly encountered clinical problem in all age groups whether benign or malignant. Fine Needle Aspiration Cytology (FNAC) of the thyroid lesions along with hormonal function test helps in the proper preoperative assessment. Ultimately it changes clinical management and improves the patient outcome.Objectives: To describe the cytomorphological features of palpable thyroid nodules using fine needle aspiration cytology (FNAC) along with the assessment of thyroid hormonal status of the patient.Methods: The study was conducted in the Department of Pathology of Gandaki Medical College and Teaching hospital from January 2017 to December 2017 and included 50 patients with thyroid lesions. Cytological assessment was done using FNAC along with serological assessment of thyroid hormones.Results: In the study 50 cases of thyroid swelling were included and evaluated by cytological and hormonal analysis which comprises of 10% males and 90% females with a with a female to male ratio of 9 : 1. Maximum number of cases was seen in the age range 41 - 60 years (46%), mean age being 44.6 years. The cytological diagnosis comprised colloid goiter (58%), lymphocytic thyroiditis (16%), Hashimoto thyroiditis (10%). Thyroid hormone analysis showed 66% euthyroid, 22% hypothyroid and 12% hyperthyroid.Conclusions: The study showed that FNAC and TFT profile both are essential for the proper management of thyroid lesions. FNAC along with hormonal analysis helps in proper patient assessment and management. J-GMC-N | Volume 11 | Issue 01 | January-June 2018, Page: 17-22 

scholarly journals Study of Thyroid Lesions by Fine Needle Aspiration Cytology and its Correlation with Thyroid Function Test

2013 ◽  
Vol 1 (1) ◽  
pp. 28
Author(s):  
Anuj Paudel ◽  
S K Jain
Keyword(s):  
Thyroid Function ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Thyroid Function Tests ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Function Tests ◽  
Needle Aspiration Cytology ◽  
Thyroid Lesions

  Introduction: Fine needle aspiration cytology (FNAC) of the thyroid gland has been widely and successfully utilized for diagnosis. Assessment of thyroid pathology is even more informative if correlated with thyroid function tests (TFT). This study aims to compare the efficacy of fine needle aspiration cytology with thyroid function tests in different thyroid lesions.   Methods: A descriptive study was carried out among the patients who presented with thyroid swellingvisiting Department of Ear Nose Throat (ENT) of Lumbini Medical College and Teaching Hospital (LMCTH) fromJune 2012 to February 2013. The study population were selected on random basis. A total of fifty patients involved in the study and were sent to Department of Pathology for FNAC and TFT.   Results: Most of the cases (44%) of thyroid swelling were from 21 to 40 years of age. Among them, 86% were females. Out of total respondents, 48% were found to be colloid goiter. 70% findings of FNAC and TFT were in accordance.   Conclusions: The findings of FNAC and TFT were found to be significantly associated (P value <0.05).

scholarly journals Diagnostic accuracy of fine-needle aspiration cytology in diagnosis of thyroid nodules

2016 ◽  
Vol 5 (1) ◽  
pp. 106
Author(s):  
Gopal Krishna Damle ◽  
Ajit Vikram Daharwal
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Thyroid Function Tests ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Neoplastic Lesion ◽  
Needle Aspiration Cytology ◽  
Method Of Evaluation

Background: Thyroid nodules are a common clinical problem Epidemiologic studies have shown the prevalence of palpable thyroid nodules to be approximately 5% in women and 1% in men living in iodine- sufficient parts of the world. The prevalence of thyroid nodules ranges from 4% to 10% in the general adult population and from 0.2% to 1.2% in children. Currently, many investigations including diagnostic imaging studies, serologic and cytogenetic tests as well as histopathological techniques are available to evaluate to evaluate thyroid nodules out. Of all these investigations, fine needle aspiration cytology (FNAC) has become the diagnostic tool of choice for the initial evaluation of solitary thyroid nodule.Methods: A present prospective study was conducted in department of ENT, Dr. BRAM hospital, Pt. JNM Medical College, Raipur, Chhattisgarh, India during study period November 2011 to October 2012. Patients with thyroid nodule were selected for the study. After taking a detailed clinical history, all cases were underwent a thorough ENT and head and neck examination. The clinical findings were recorded. Thyroid function tests and other necessary investigations were also done. Then the patients were referred for fine needle aspiration cytology to the department of Pathology. Depending on the nature of the lesion, decision had taken regarding need for surgery and the extent of surgery. All fine needle aspiration cytology (FNAC) reports were correlated with histopathology diagnosis.Results: Male and female ratio was 1:3.5. Preoperatively FNAC done in 54 cases out of which 36 (66.66%) results were goiter followed by 4 (7.40%) hurthle cell thyroiditis and 2 (3.87%) chronic thyroditis Among 54 cases 1.85% results were follicular neoplasia followed by 3 (5.55%). Fine needle aspiration cytology was 87.5% sensitive in detection of neoplastic lesion and 95.65% sensation of neoplastic lesion and 95.65% specific. Accuracy was 94.44%.Conclusions: Fine needle aspiration cytology is a simple, rapid, inexpensive, well tolerated and harmless method of evaluation mass lesions of the neck especially when there is a close cooperation between the clinician and cytopathologist.

B cell lymphoma of the thyroid in hashimoto's thyroiditis monitored by fine-needle aspiration cytology

1990 ◽  
Vol 6 (2) ◽  
pp. 130-133 ◽  
Author(s):  
Gita Jayaram ◽  
Sudha Rani ◽  
Vinita Raina ◽  
Col Harcharan Singh ◽  
Mithilesh Chandra ◽  
...  
Keyword(s):  
B Cell ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Cell Lymphoma ◽  
B Cell Lymphoma ◽  
Needle Aspiration ◽  
Hashimoto's Thyroiditis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology
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