scholarly journals Immunoreactivity and trypsin sensitivity of recombinant virus-like particles of foot-and-mouth disease virus

2015 ◽  
Vol 59 (01) ◽  
pp. 84-91 ◽  
Author(s):  
S. H. BASAGOUDANAVAR ◽  
M. HOSAMANI ◽  
R. P. TAMIL ◽  
B. P. SREENIVASA ◽  
B. K. CHANDRASEKHAR ◽  
...  
2018 ◽  
Vol 244 ◽  
pp. 213-217 ◽  
Author(s):  
Varusha Pillay Veerapen ◽  
Albertha R. van Zyl ◽  
Andrés Wigdorovitz ◽  
Edward P. Rybicki ◽  
Ann E. Meyers

2012 ◽  
Vol 96 (3) ◽  
pp. 288-295 ◽  
Author(s):  
B. Mohana Subramanian ◽  
M. Madhanmohan ◽  
Rajan Sriraman ◽  
R.V. Chandrasekhar Reddy ◽  
S. Yuvaraj ◽  
...  

2016 ◽  
Vol 54 (5) ◽  
pp. 597
Author(s):  
Nguyen Hoang Duong ◽  
Chi-Ning Chuang ◽  
Nguyen Phuong Hoa ◽  
Tran Thi Kim Dung ◽  
Le Hong Minh ◽  
...  

Foot and mouth disease virus (FMDV) causing infectious disease affects broadly cloven-hoofed animals. It has 7 different serotypes. However O is the most prevalent type in 3 founded types (O, A, Asia1) recurrence in Vietnam fields. The current vaccine for FMDV is inactivated or attenuated forms. Vaccines were able to raise strong immune responses but still caused the safety concerns. Virus-like particles could be a new vaccine generation that fulfills the present questions. On the one hand, it can tackle the safety issues, on the other hand, it can reserve FMDV intrinsic form which will provoke high immunogenicity. The important initial step to make virus-like particles is expression the capsid proteins of FMDV in appropriate system. So this study we describe how to design, express and purify of all capsid proteins: VP0, VP1 and VP3 of O type FMDV isolated in Vietnam field using SUMO fusion expression system.


1969 ◽  
Vol 15 (1) ◽  
pp. 138-140 ◽  
Author(s):  
K. S. Tsai ◽  
I. Grinyer ◽  
I. C. Pan ◽  
L. Karstad

Aggregates of virus-like particles, which measured about 25 mμ in diameter in the form of crystalline arrays, were observed in the tissues of mink experimentally infected with Aleutian disease (AD). Such structures were not observed in normal control mink. The similarity between these structures and the viral crystals of porcine polioencephalomyelitis and early foot-and-mouth disease virus crystals is emphasized.


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