Metabotropic glutamate receptor 5-negative allosteric modulators for the treatment of psychiatric and neurological disorders (2009–July 2013)

2013 ◽  
Vol 2 (6) ◽  
pp. 767-802 ◽  
Author(s):  
Guiying Li ◽  
Morten Jørgensen ◽  
Brian M Campbell
Keyword(s):  
Glutamate Receptor ◽  
Neurological Disorders ◽  
Metabotropic Glutamate Receptor ◽  
Allosteric Modulators ◽  
Metabotropic Glutamate Receptor 5 ◽  
Metabotropic Glutamate

scholarly journals Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators

2017 ◽  
Vol 24 (7) ◽  
pp. 858-869.e5 ◽  
Author(s):  
Falgun Shah ◽  
Antonia F. Stepan ◽  
Alison O'Mahony ◽  
Sharlene Velichko ◽  
Alexandra E. Folias ◽  
...  
Keyword(s):  
Glutamate Receptor ◽  
Metabotropic Glutamate Receptor ◽  
Skin Toxicity ◽  
Allosteric Modulators ◽  
Metabotropic Glutamate Receptor 5 ◽  
Metabotropic Glutamate

A novel series of metabotropic glutamate receptor 5 negative allosteric modulators based on a 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine core

2013 ◽  
Vol 23 (16) ◽  
pp. 4523-4527 ◽  
Author(s):  
Guillaume Duvey ◽  
Benjamin Perry ◽  
Emmanuel Le Poul ◽  
Sonia Poli ◽  
Beatrice Bonnet ◽  
...  
Keyword(s):  
Glutamate Receptor ◽  
Metabotropic Glutamate Receptor ◽  
Allosteric Modulators ◽  
Metabotropic Glutamate Receptor 5 ◽  
Metabotropic Glutamate

scholarly journals Development of 1H-Pyrazolo[3,4-b]pyridines as Metabotropic Glutamate Receptor 5 Positive Allosteric Modulators

2016 ◽  
Vol 7 (12) ◽  
pp. 1082-1086 ◽  
Author(s):  
Matthew D. Hill ◽  
Haiquan Fang ◽  
Jeffrey M. Brown ◽  
Thaddeus Molski ◽  
Amy Easton ◽  
...  
Keyword(s):  
Glutamate Receptor ◽  
Metabotropic Glutamate Receptor ◽  
Allosteric Modulators ◽  
Metabotropic Glutamate Receptor 5 ◽  
Metabotropic Glutamate ◽  
Positive Allosteric Modulators
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