scholarly journals Periostin in Exhaled Breath Condensate and in Serum of Asthmatic Patients: Relationship to Upper and Lower Airway Disease

2017 ◽  
Vol 9 (2) ◽  
pp. 126 ◽  
Author(s):  
Aleksandra Wardzyńska ◽  
Joanna S. Makowska ◽  
Małgorzata Pawełczyk ◽  
Aleksandra Piechota-Polańczyk ◽  
Marcin Kurowski ◽  
...  
2016 ◽  
Vol 129 (7) ◽  
pp. 819-823 ◽  
Author(s):  
Chun-Hua Chi ◽  
Ji-Ping Liao ◽  
Yan-Ni Zhao ◽  
Xue-Ying Li ◽  
Guang-Fa Wang

2005 ◽  
Vol 169 (3) ◽  
pp. 385-396 ◽  
Author(s):  
Nathalie Kirschvink ◽  
David Marlin ◽  
François Delvaux ◽  
Jérôme Leemans ◽  
Cécile Clercx ◽  
...  

2014 ◽  
Vol 13 (12) ◽  
pp. 6107-6120 ◽  
Author(s):  
Andrea Motta ◽  
Debora Paris ◽  
Maria D’Amato ◽  
Dominique Melck ◽  
Cecilia Calabrese ◽  
...  

2010 ◽  
Vol 47 (9) ◽  
pp. 1057-1062 ◽  
Author(s):  
András Bikov ◽  
Réka Gajdócsi ◽  
Éva Huszár ◽  
Balázs Szili ◽  
Zsófia Lázár ◽  
...  

2004 ◽  
Vol 6 (5) ◽  
pp. 335-338 ◽  
Author(s):  
Andrew H. Sparkes ◽  
Eleanor J. Mardell ◽  
Chris Deaton ◽  
Nathalie Kirschvink ◽  
David Marlin

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Michael J. Coffey ◽  
Barbara Torretti ◽  
Peter Mancuso

Background. The prevalence of obesity has increased dramatically over the last decades, and its association with asthma is being increasingly recognized. Aims. Our hypothesis is that increased leptin and decreased adiponectin levels in obese subjects play a direct role in regulating inflammation in asthmatics. We wanted to examine the hypothesis that cysteinyl leukotrienes (cys-LT), inflammatory mediators that are regulated by adipokines, are involved in the pathogenesis of asthma. Methods. We studied a population of asthmatics and nonasthmatics, who in turn were divided into obese and nonobese categories. We examined leptin and its ratio to adiponectin, in asthmatics and nonasthmatics, with and without obesity. In addition, we measured cys-LT levels in exhaled breath condensate (EBC) and in peripheral blood monocytes (PBM) in these groups. Results. Leptin levels were increased in obese asthmatics compared to obese nonasthmatics. The leptin/adiponectin (L/A) ratio was higher in obese asthmatics compared to obese nonasthmatics. EBC cys-LT levels were elevated in asthmatics compared to nonasthmatics. Discussion. Proinflammatory adipokines, released from adipose tissue, may promote an asthma phenotype through enhanced cys-LT production that may result in more prevalent and difficult to control airway disease.


2002 ◽  
Vol 109 (1) ◽  
pp. S23-S23 ◽  
Author(s):  
John W Vaughan ◽  
Benjamin M Gaston ◽  
Thomas Pajewski ◽  
John F Hunt

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