scholarly journals Long-term Outcomes of Combined Cataract Surgery and Trabeculotomy using Trabectome for Coexisting Cataract and Open-angle Glaucoma: A 5 Year Follow-Up

2018 ◽  
Vol 09 (05) ◽  
Author(s):  
Arezoo Miraftabi ◽  
Seyed Javad Hashemian ◽  
Leila Sasani ◽  
Mohammad Ebrahim Jafari ◽  
Mahsa Hashemian
Keyword(s):  
Cataract Surgery ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Long Term Outcomes

scholarly journals Long-term outcomes of two first-generation trabecular micro-bypass stents (iStent) with phacoemulsification in primary open-angle glaucoma: eight-year results

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Ali Salimi ◽  
Harrison Watt ◽  
Paul Harasymowycz
Keyword(s):  
Cataract Surgery ◽  
First Generation ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Long Term Outcomes ◽  
Surgical Success ◽  
Rnfl Thickness

Abstract Background The short- and medium-term outcomes of iStent have been extensively studied; however, only few studies have investigated its long-term outcomes. Here, we assessed the long-term efficacy and safety of two iStents with concomitant cataract surgery in glaucomatous eyes while also evaluating measures of disease stability using visual field and optical coherence tomography (OCT) of the optic nerve and the macula throughout 8 years of follow-up. Methods This longitudinal, single-center consecutive case series included glaucomatous eyes that underwent implantation of two first-generation trabecular micro-bypass stents (iStent) with concomitant cataract surgery. Eight-year efficacy outcomes included mean intraocular pressure (IOP) and medications, as well as surgical success. Eight-year safety outcomes included best-corrected visual acuity (BCVA), visual field mean deviation (VF-MD), cup-to-disc ratio (CDR), retinal nerve fiber layer (RNFL) thickness, ganglion cell-inner plexiform layer (GC-IPL) thickness, and adverse events. Results A total of 62 eyes with primary open-angle glaucoma (POAG) were included. At 8 years postoperative, IOP reduced by 26% from 19.2 ± 3.9 mmHg preoperatively to 14.2 ± 2.4 mmHg (P < 0.001), 91.1% of eyes achieved IOP ≤ 18 mmHg (vs. 51.6% preoperatively), 69.6% of eyes achieved IOP ≤ 15 mmHg (vs. 14.5% preoperatively), and 25% of eyes achieved IOP ≤ 12 mmHg (vs. 1.6% preoperatively). Medication use decreased by 17.9% from 2.8 ± 1.1 preoperatively to 2.3 ± 1.2 (P = 0.018). Surgical success was 90%, as six eyes underwent subsequent glaucoma surgeries. Safety measures of BCVA, CDR, RNFL thickness and GC-IPL thickness remained stable through 8 years postoperative. VF-MD remained stable until postoperative year 5 and subsequently progressed according to the natural history of glaucomatous disease. Conclusions Implantation of two iStents with concomitant cataract surgery is an effective and safe treatment option for surgery-naïve POAG eyes, evidenced by significant IOP and medication reductions, reasonable surgical success, and favorable safety outcomes, throughout the 8-year follow-up. Our data additionally supports the efficacy of this combined procedure in stabilizing or slowing disease progression.

scholarly journals Micro-Bypass Implantation for Primary Open-Angle Glaucoma Combined with Phacoemulsification: 4-Year Follow-Up

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Antonio Maria Fea ◽  
Giulia Consolandi ◽  
Marta Zola ◽  
Giulia Pignata ◽  
Paola Cannizzo ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Control Group ◽  
Open Angle ◽  
Long Term Follow Up ◽  
Baseline Values ◽  
The Mean

Purpose. To report the long-term follow-up results in patients with cataract and primary open-angle glaucoma (POAG) randomly assigned to cataract surgery combined with micro-bypass stent implantation or phacoemulsification alone.Methods. 36 subjects with cataract and POAG were randomized in a 1 : 2 ratio to either iStent implantation and cataract surgery (combined group) or cataract surgery alone (control group). 24 subjects agreed to be evaluated again 48 months after surgery. Patients returned one month later for unmedicated washout assessment.Results. At the long-term follow-up visit we reported a mean IOP of 15,9 ± 2,3 mmHg in the iStent group and 17 ± 2,5 mmHg in the control group (p=NS). After washout, a 14,2% between group difference in favour of the combined group was statistically significant (p=0,02) for mean IOP reduction. A significant reduction in the mean number of medications was observed in both groups compared to baseline values (p=0,005in the combined group andp=0,01in the control group).Conclusion. Patients in the combined group maintained low IOP levels after long-term follow-up. Cataract surgery alone showed a loss of efficacy in controlling IOP over time. Both treatments reduced the number of ocular hypotensive medications prescribed. This trial is registered with:NCT00847158.

scholarly journals Glaukos iStent inject® Trabecular Micro-Bypass Implantation Associated with Cataract Surgery in Patients with Coexisting Cataract and Open-Angle Glaucoma or Ocular Hypertension: A Long-Term Study

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Pedro Arriola-Villalobos ◽  
Jose Maria Martinez-de-la-Casa ◽  
David Diaz-Valle ◽  
Laura Morales-Fernandez ◽  
Cristina Fernandez-Perez ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Ocular Hypertension ◽  
Open Angle Glaucoma ◽  
Case Series ◽  
Open Angle ◽  
Long Term Study ◽  
Case Series Study ◽  
Complications Of Surgery

Purpose. To evaluate the long-term efficacy and safety of the iStentinjectdevice (Glaukos Corporation, Laguna Hills, CA) combined with phacoemulsification in patients with coexistent cataract and open-angle glaucoma or ocular hypertension (OHT).Methods. A prospective, uncontrolled, nonrandomized, interventional case series study was conducted in patients with both mild or moderate open-angle glaucoma or OHT and cataract. Patients underwent cataract surgery along with the implant of two iStentinjectdevices. Outcome measures were intraocular pressure (IOP), topical hypotensive medications required, and best-corrected visual acuity (BCVA).Results. 20 patients were enrolled. Mean follow-up was47.4±18.46months. Mean baseline IOP was19.95±3.71 mmHg with medication and26±3.11 mmHg after washout. Mean end-follow-up IOP was16.25±1.99 mmHg, representing an IOP decrease of 36.92%,9.74±3.14 mmHg (P<0.001), from baseline washout IOP. The mean number of medications was significantly reduced from1.3±0.66to0.75±0.79(P=0.017). 45% of patients were medication-free by the end of follow-up. Meanlog⁡MARBCVA improved significantly from0.42±0.16to0.18±0.16(P<0.001). No complications of surgery were observed.Conclusion. The iStentinjectdevice combined with cataract surgery served to significantly reduce both IOP and medication use in the long term in patients with coexistent open-angle glaucoma or ocular hypertension (OHT) and cataract.

Long-Term Follow-up in Preperimetric Open-Angle Glaucoma: Progression Rates and Associated Factors

2015 ◽  
Vol 159 (1) ◽  
pp. 160-168.e2 ◽  
Author(s):  
Ko Eun Kim ◽  
Jin Wook Jeoung ◽  
Dong Myung Kim ◽  
Seong Joon Ahn ◽  
Ki Ho Park ◽  
...  
Keyword(s):  
Associated Factors ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Glaucoma Progression ◽  
Long Term Follow Up

scholarly journals Open-angle glaucoma and mortality: A long-term follow-up study

2018 ◽  
Vol 96 (8) ◽  
pp. e1038-e1039
Author(s):  
Julius Sundqvist ◽  
Curt Ekström
Keyword(s):  
Open Angle Glaucoma ◽  
Open Angle ◽  
Follow Up Study ◽  
Long Term Follow Up

Long-term Follow-up of Diode Laser Trabeculoplasty for Primary Open-angle Glaucoma and Ocular Hypertension

Ophthalmology ◽  
1993 ◽  
Vol 100 (11) ◽  
pp. 1614-1618 ◽  
Author(s):  
Anthony P. Moriarty ◽  
J. Dominic A. McHugh ◽  
Timothy J. ffytche ◽  
John Marshall ◽  
A.M. Peter Hamilton
Keyword(s):  
Ocular Hypertension ◽  
Diode Laser ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Laser Trabeculoplasty ◽  
Long Term Follow Up

scholarly journals Trabeculectomy with Ologen implant versus perfluoropropane gas bubble for open angle glaucoma in pseudophakic eyes

2021 ◽  
Vol 14 (4) ◽  
pp. 510-516
Author(s):  
Ahmed S Elwehidy ◽  
◽  
Hossam Youssef Abouelkheir ◽  
Waleed Abou Samra ◽  
Faried M Wagdy ◽  
...  
Keyword(s):  
Open Angle Glaucoma ◽  
Randomized Study ◽  
Study Groups ◽  
Gas Bubble ◽  
Open Angle ◽  
Safety And Efficacy ◽  
Group I ◽  
The Mean

AIM: To evaluate the safety and efficacy of augmented trabeculotomy with Ologen versus perfluoropropane in management of pseudophakic glaucoma. METHODS: This is a comparative randomized study included 57 pseudophakic eyes of 57 patients with medically uncontrolled open angle glaucoma (OAG). Twenty-nine patients were allocated in group I (trabeculectomy with Ologen; trab-ologen group), while 28 patients were assigned in group II (trabeculectomy with perfluoropropane gas bubble; trab-C3F8 gas bubble group). RESULTS: The intraocular pressure (IOP) was significantly reduced in both study groups at all postoperative follow up intervals (1wk, 3, 6, 12, 18, 24, 30 and 36mo, P&#x0026;#x003C;0.001). The differences between the mean IOP values of both groups remained statistically insignificance during the early 12 months of follow up. However, the trab-ologen group achieved a statistically significant reduction over the trab-C3F8 gas bubble group during the last 24 months of follow up. CONCLUSION: Augmentation of trabeculectomy with either Ologen implant or perfluoropropane gas bubble are associated with strict long term IOP control and evident safety in medically-uncontrolled pseudophakic eyes with OAG.

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