Organophosphorous pesticides poisoning can result from occupational, accidental or intentional exposure. Clinical manifestations include cholinergic syndromes, central nervous system and cardiovascular disorders Death is usually due to cardiovascular& respiratory failure.Material & methods: This case series was conducted in department Medicine AIMS, Bangalore from July 2013 to June 2014. Detailed history & clinical examination was done. Diagnosis of OP poisoning was based on clinical features, history of exposure to a known OP compound and low serum Achcholiesterase & pseudocholiesterase activity.Results: Out of one thirty three, one hundred and thirty (82.66%) patients ingested the compound, 23 (7.6%) & only three patients had dermal / inhaled exposure while spraying pesticides in rice fields. In our study female to male ratio in was 1: 3.2, age ranged from 13 to 50 years with mean age was 31.5 years. Acute complications were frequently noted and were related to morbidity & mortality. Most consistent clinical symptoms were miosis 93.6%, increased salivation 86.4%, anxiety and restlessness 82.7%, bronchospam 78.1% and incontinence in 58%.Conclusion: In OP acute complications are seen more frequently and are related to mortality & morbidity. The importance of rapid diagnosis, early and effective treatment should not be overlooked because patients who receive early& effective treatment generally will do better and have less complication and severity of poisoning.J MEDICINE January 2016; 17 (1) : 3-7
Artificial liver support system in pediatric acute liver failure due to mushroom poisoning: case series
