Comparison of Optimal Positive End-Expiratory Pressure and Recruitment Maneuvers During Lung-Protective Mechanical Ventilation in Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome

2009 ◽  
Vol 54 (7) ◽  
pp. 847-854 ◽  
Author(s):  
Michel Badet ◽  
Frédérique Bayle ◽  
Jean-Christophe Richard ◽  
Claude Guérin
Keyword(s):  
Mechanical Ventilation ◽  
Acute Respiratory Distress Syndrome ◽  
Acute Lung Injury ◽  
Lung Injury ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Positive End Expiratory Pressure ◽  
Protective Mechanical Ventilation ◽  
Lung Protective Mechanical Ventilation

scholarly journals Acute Respiratory Distress Syndrome: Insights Gained from Clinical and Translational Research

2009 ◽  
Vol 9 (1) ◽  
pp. S59-S68 ◽  
Author(s):  
Marija Kojicic ◽  
Emir Festic ◽  
Ognjen Gajic
Keyword(s):  
Mechanical Ventilation ◽  
Acute Respiratory Distress Syndrome ◽  
Lung Injury ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Severe Form ◽  
Ventilator Induced Lung Injury ◽  
Protective Mechanical Ventilation ◽  
Lung Protective Mechanical Ventilation

Acute lung injury and its more severe form acute respiratory distress syndrome (ARDS) are characterized by diffuse impairment of alveolocapillary membrane in the settings of different predisposing conditions such as sepsis, trauma and shock. Many intrahospital exposures, including aspiration, delayed resuscitation, high tidal volume mechanical ventilation and non critical use of transfusions may contribute or worsen ARDS. Therapy is targeted to treatment of predisposing condition, life supportive measures and prevention of nosocomial complications. Rigorous adherence to lung-protective mechanical ventilation is critical to prevent ventilator induced lung injury and decrease mortality. Although survival of ARDS patients has improved in the last decades ARDS mortality rates are still high and survivors encounter significant physical and psychological impairments

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