scholarly journals Treatment with a topical glucocorticoid, budesonide, reduced the variability of rhinomanometric nasal airway resistance

2014 ◽  
Vol 52 (1) ◽  
pp. 19-24
Author(s):  
H.L. Thulesius ◽  
A. Cervin ◽  
M. Jessen
Keyword(s):  
Visual Analogue Scale ◽  
Healthy Volunteers ◽  
Nasal Obstruction ◽  
Analogue Scale ◽  
Airway Resistance ◽  
Nasal Airway ◽  
Nasal Airway Resistance ◽  
The Mean ◽  
Active Anterior Rhinomanometry

Background: Previous rhinomanometry studies have shown significant long-term variability of the nasal airway resistance and questioned the clinical validity of rhinomanometry. Research question: Could treatment with a topical glucocorticoid, budesonide, influence the long-term variability of active anterior rhinomanometry? Methods: Eight healthy volunteers participated in an unblinded controlled trial without, and later with, nasal budesonide once a day for 5 months. Their nasal airway resistance was measured every two weeks with active anterior rhinomanometry before and after decongestion with xylometazoline hydrochloride. In addition, subjective nasal obstruction was evaluated on a Visual Analogue Scale before each measurement. The participants had a year earlier been investigated with rhinomanometry every two weeks during 5 months but without budesonide treatment. We compared the variability of nasal airway resistance during the two periods with and without treatment with topical budesonide. Results: Budesonide significantly reduced mean nasal airway resistance and the standard deviation of the mean after decongestion for 6 of 8 participants. The mean reduction of the nasal airway resistance was 40% for the decongested nasal cavity compared to the period without treatment with nasal budesonide. Subjective nasal obstruction assessed by Visual Analogue Scale was reduced in 3 of the 8 participants. Conclusion: The variability of nasal airway resistance was significantly reduced by treatment with topical budesonide for 6 out of 8 healthy volunteers participating in an unblinded repeated 5 month trial where the participants served as their own controls.

An Evaluation of Active Anterior and Posterior Rhinomanometry in British Adults

1996 ◽  
Vol 10 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Ercan I. Canbay ◽  
Suren N. Bhatia
Keyword(s):  
Airway Resistance ◽  
Repeated Measurements ◽  
Nasal Airway ◽  
Mean Values ◽  
Nasal Decongestant ◽  
Nasal Airway Resistance ◽  
On Line ◽  
The Mean ◽  
Reference Pressure ◽  
Active Anterior Rhinomanometry

In this study, active Anterior Rhinomanometry (ARM) and Posterior Rhinomanometry (PRM) were performed sequentially by 56 normal British Caucasian adults using an on-line Mercury Electronics NR6D Rhinomanometer. Xylometazoline nasal spray was used as a nasal decongestant before the test. In addition, repeated measurements were made on a randomly selected 13 subjects to evaluate the error of the methods. The mean total nasal airway resistance by the anterior method was found to be 0.182 Pa/cm3/s at a reference pressure of 150 Pascals, and by the posterior method 0.166 Pa/cm3/s at a reference pressure of 75 Pascals. These mean values are similar to those reported by other authors for Caucasians. The errors of the methods were found to be smaller than previously reported (Coefficient of variation, ARM = 6.9%; PRM = 7.7%). The total nasal airway resistance was higher during expiration than inspiration, and higher in women than in men. The ARM values were on an average 9% higher than those of the PRM, and the association between the two values was found to be moderate (r = 0.48). The higher ARM mean values could be attributed to inappropriateness of the conventional Ohm's law used in their calculation. For a number of reasons, PRM is considered to be more suitable than ARM for measuring nasal resistance.

scholarly journals Relationship between Nasal Airway Resistance and Sensation of Nasal Patency Evaluated by Visual Analogue Scale

2003 ◽  
Vol 42 (2) ◽  
pp. 99-105
Author(s):  
Satoshi Nonaka ◽  
Masaaki Adachi ◽  
Isamu Kunibe ◽  
Akihiro Katada ◽  
Masanobu Imada ◽  
...  
Keyword(s):  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Airway Resistance ◽  
Nasal Airway ◽  
Nasal Patency ◽  
Nasal Airway Resistance

Active anterior rhinomanometry analysis in normal adult Malays

2003 ◽  
Vol 117 (8) ◽  
pp. 605-608 ◽  
Author(s):  
A. H. Suzina ◽  
M. Hamzah ◽  
A. R. Samsudin
Keyword(s):  
Airway Resistance ◽  
Objective Assessment ◽  
Nasal Airway ◽  
Nasal Resistance ◽  
Clinical Method ◽  
Pressure Point ◽  
Nasal Airway Resistance ◽  
The Mean ◽  
Reference Pressure ◽  
Active Anterior Rhinomanometry

The differences in facial anatomical structures of the major ethnic groups,may also be reflected in nasal resistance. Active anterior rhinomanometry (AAR) is the recommended technique for the objective assessment of nasal airway resistance (NAR). This study comprised of 85 adult Malay subjects. All the subjects had to undergo a primary assessment of relevantsymptoms of nasal disease and nasal examination before undergoing AAR assessment. The mean value of total nasal airway resistance (NAR) was 0.19 Pa/cm3/s (ranged from 0.09 to 0.55Pa/cm3/s) at 75 Pa pressure point and 0.24 Pa/cm3/s ranged from 0.12 to 0.52 Pa/cm3/s) at 150 Pa pressure point. The mean unilateral NARwas 0.46 Pa/cm3/s at a reference pressure of 75 Pa and 0.51 Pa/cm3/s at a reference pressure of 150 Pa. In this study we presented normal values for NAR in healthy Malay adult subjects. AARproves to be a valuable clinical method for recording and quantitating nasal resistance.

The Role of Mucosal Oedema in Nasal Obstruction in Patients with Septal Pathology

1995 ◽  
Vol 9 (4) ◽  
pp. 211-216 ◽  
Author(s):  
Jouko T. Suonpää ◽  
Jukka I. Sipilä
Keyword(s):  
Nasal Obstruction ◽  
Airway Resistance ◽  
Nasal Airway ◽  
Control Material ◽  
Nasal Airway Resistance ◽  
Mucosal Edema ◽  
Mucosal Oedema ◽  
The Mean ◽  
Mucosal Hypertrophy

The degree of mucosal edema was assessed using the decongestion effect achieved with vasoconstrictor spray in 102 patients referred for septoplasty. In preoperative rhinomanometry it was found that 62 patients had high postdecongestion nasal airway resistance (NAR) compared with control material, whereas in 40 cases, NAR was normal before operation. Our results show that the decongestion effect was higher, both pre- and postoperatively, in patients with high preoperative postdecongestion NAR. Although surgery succeeded in normalizing the mean decongestion values in these patients, there still remained considerable mucosal congestion compared to cases with low preoperative resistance. We conclude that a marked septal structural pathology causes not only high postdecongestion resistance, but that abnormal structures of the nasal airway also cause mucosal hypertrophy, mucosal irritation, and inflammation, which is measurable with rhinomanometry as elevated baseline resistance and higher decongestion effect.

scholarly journals Current guidelines for nut consumption are achievable and sustainable: a hazelnut intervention

2011 ◽  
Vol 105 (10) ◽  
pp. 1503-1511 ◽  
Author(s):  
S. L. Tey ◽  
R. Brown ◽  
A. Chisholm ◽  
A. Gray ◽  
S. Williams ◽  
...  
Keyword(s):  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Exposure Period ◽  
Long Term Effects ◽  
Stage Design ◽  
Regular Consumption ◽  
Optimal Health ◽  
The Mean ◽  
Current Guidelines

Nuts are known for their hypocholesterolaemic properties; however, to achieve optimal health benefits, nuts must be consumed regularly and in sufficient quantity. It is therefore important to assess the acceptability of regular consumption of nuts. The present study examined the long-term effects of hazelnut consumption in three different forms on ‘desire to consume’ and ‘overall liking’. A total of forty-eight participants took part in this randomised cross-over study with three dietary phases of 4 weeks: 30 g/d of whole, sliced and ground hazelnuts. ‘Overall liking’ was measured in a three-stage design: a pre- and post-exposure tasting session and daily evaluation over the exposure period. ‘Desire to consume’ hazelnuts was measured during the exposure period only. Ratings were measured on a 150 mm visual analogue scale. Mean ratings of ‘desire to consume’ were 92 (sd 35) mm for ground, 108 (sd 33) mm for sliced and 116 (sd 30) mm for whole hazelnuts. For ‘overall liking’, the mean ratings were 101 (sd 29) mm for ground, 110 (sd 32) mm for sliced and 118 (sd 30) mm for whole hazelnuts. Ground hazelnuts had significantly lower ratings than both sliced (P ≤ 0·034) and whole hazelnuts (P < 0·001), with no difference in ratings between sliced and whole hazelnuts (P ≥ 0·125). For each form of nut, ratings of ‘overall liking’ and ‘desire to consume’ were stable over the exposure period, indicating that not only did the participants like the nuts, but also they wished to continue eating them. Therefore, the guideline to consume nuts on a regular basis appears to be a sustainable behaviour to reduce CVD.

scholarly journals Nasal obstruction causes a decrease in lip-closing force

2011 ◽  
Vol 81 (5) ◽  
pp. 750-753 ◽  
Author(s):  
Kishio Sabashi ◽  
Kaei Washino ◽  
Issei Saitoh ◽  
Youichi Yamasaki ◽  
Atsushi Kawabata ◽  
...  
Keyword(s):  
Nasal Obstruction ◽  
Airway Resistance ◽  
Correlation Coefficients ◽  
Significant Negative Correlation ◽  
Normal Group ◽  
Nasal Airway ◽  
Nasal Airway Resistance ◽  
Obstruction Group ◽  
Closing Force ◽  
Group A

Abstract Objective: To investigate the relationship between nasal obstruction and lip-closing force. Materials and Methods: Nasal airway resistance and lip-closing force measures were recorded for 54 Japanese females. The subjects were classified into normal and nasal obstruction groups according to nasal airway resistance values. Differences between the normal and nasal obstruction groups in lip-closing force were tested statistically. Correlation coefficients were calculated between the measures for the normal and nasal obstruction groups. Results: Lip-closing force for the nasal obstruction group was significantly less than for the normal group (P &lt; .05). In the normal group, nasal airway resistance did not correlate with lip-closing force, while in the nasal obstruction group a significant negative correlation was found between nasal airway resistance and lip-closing force (P &lt; .05). Conclusions: Nasal obstruction is associated with a decrease in lip-closing force. When the severity of nasal obstruction reaches a certain level, the lip-closing force is weakened.

scholarly journals Paradoxical increase in nasal airway resistance following a topical nasal decongestant spray

2011 ◽  
Vol 49 (1) ◽  
pp. 127-127
Author(s):  
N.M. Doddi ◽  
R. Eccles
Keyword(s):  
Nasal Obstruction ◽  
Common Cold ◽  
Airway Resistance ◽  
Nasal Airway ◽  
Nasal Decongestant ◽  
Nasal Airway Resistance

Nasal obstruction is a very common problem associated with common cold and topical nasal decongestant sprays are effective symptomatic treatments causing a decrease in nasal airway resistance (NAR).

Comparing the effectiveness of nasal dilator strips: does race play a role?

2014 ◽  
Vol 129 (S1) ◽  
pp. S51-S56 ◽  
Author(s):  
A W Kam ◽  
E Pratt ◽  
R J Harvey
Keyword(s):  
Analogue Scale ◽  
Airway Resistance ◽  
Inspiratory Flow ◽  
Nasal Airway ◽  
Sectional Area ◽  
Cross Sectional ◽  
Peak Inspiratory Flow ◽  
Nasal Airway Resistance ◽  
Nasal Dilator Strips ◽  
Nasal Peak Inspiratory Flow

AbstractBackground:Nasal dilator strips are thought to widen and stiffen the anterior nasal cavity, and thus improve symptoms of nasal obstruction. It is postulated that anthropomorphic differences in external nasal proportions between races may influence the effectiveness of such dilator strips.Methods:Caucasian and Asian subjects were compared. Nasal peak inspiratory flow, nasal airway resistance, minimum cross-sectional area and visual analogue scale measurements of nasal obstruction were recorded at baseline and following the application of two different dilator strips.Results:Nine Caucasian and six Asian subjects were recruited (n = 15). There was a significant difference between races in terms of nasal peak inspiratory flow improvements following nasal strip application (mean of 29.4 litres per minute in Caucasiansvs14.6 litres per minute in Asians;p = 0.04). Only Caucasians experienced a significant decrease in nasal airway resistance (median of 0.12 Pa/cm3/s;p < 0.01).Conclusion:Nasal peak inspiratory flow, minimum cross-sectional area and visual analogue scale values improved from baseline with strip application in both populations. Only Caucasians experienced significant nasal airway resistance improvement with strip application. Both cohorts experienced nasal peak inspiratory flow improvement, with Caucasians experiencing a significantly larger improvement.

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