Twelfth Cranial Nerve Involvement in Guillain-Barre Syndrome: A Case Report

INTRODUCTION: In this study, we aimed to revise the clinical, epidemiologic and prognostic features of childhood Guillain-Barré syndrome. METHODS: Thirty two children admitted to our hospital and diagnosed with Guillain-Barré syndrome between June 2007- November 2019 were enrolled in the study. We also administered clinical evaluation scale at onset, discharge, 1,3,6 and 12 months after discharge. RESULTS: The median age was 72.22 months (range from 6 to 202 months) with a male to female ratio of 1.46. Based on electrophysiological features; 22 patients were classified as acute inflammatory demyelinating polyradiculoneuropathy, 10 as acute motor axonal neuropathy. The incidence of cranial nerve involvement was 28.1 % and was related to lower clinical scale score at admission and discharge. Clinical scale scores were significantly different between axonal and demyelinating subgroups except for admission. At 12th month follow-up visit, 78.1% of patients were recovered without sequal. DISCUSSION AND CONCLUSION: We think that the most important predictor of morbidity is predicting the possible ventilatory support need during the follow up period. Short incubating period of antecedent infection and cranial nerve involvement will probably increase ventilatory support need. The prognosis was found to be significantly different between electrophysiological subtypes in our series, axonal forms being consistent with poor prognosis.

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Cranial nerve involvement in Guillain–Barre syndrome: Revisited

Journal of Pediatric Neurosciences ◽

10.4103/jpn.jpn_18_17 ◽

2017 ◽

Vol 12 (4) ◽

pp. 398

Author(s):

KhicharPurnaram Shubhakaran

Keyword(s):

Cranial Nerve ◽

Guillain Barre Syndrome ◽

Cranial Nerve Involvement ◽

Nerve Involvement ◽

Guillain Barré Syndrome ◽

Guillain Barré

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Case Report and Literature Analysis: Guillain-Barré Syndrome With Delayed Unilateral Facial Palsy

Frontiers in Neurology ◽

10.3389/fneur.2021.658266 ◽

2021 ◽

Vol 12 ◽

Author(s):

Xuanyu Huang ◽

Ziwei Lan ◽

Yajing Zhan ◽

Zhiping Hu

Keyword(s):

Facial Nerve ◽

Facial Palsy ◽

Guillain Barre Syndrome ◽

Facial Movement ◽

Cranial Nerve Involvement ◽

Nerve Involvement ◽

Rare Manifestation ◽

Guillain Barré Syndrome ◽

Ganglioside Antibodies ◽

Guillain Barré

Guillain-Barré syndrome (GBS) is an acute inflammatory polyradiculoneuropathy in which most patients have cranial nerve involvement, with facial nerve involvement being the most common. However, delayed facial palsy (DFP) with asymmetric facial palsy is a rare manifestation of GBS, and the mechanism is unclear. We report a case of GBS combined with delayed unilateral facial palsy and review previously reported cases of GBS combined with DFP. A total of 28 cases of GBS with DFP, including the case in this report, were included in this study. The occurrence of DFP may be related to early subclinical demyelination of the facial nerve, the blood-nerve barrier of the facial nerve, facial movement, and descending reversible paralysis. The occurrence of unilateral facial palsy may be related to Campylobacter jejuni, specific anti-ganglioside antibodies, and the site of central nervous system anatomical involvement. There is no evidence that immunotherapy is related to the shortening of DFP course and improving patients' prognosis.

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A case report of Guillain Barré syndrome revealing underlying infective endocarditis due to Cardiobacterium hominis

Medicine ◽

10.1097/md.0000000000015014 ◽

2019 ◽

Vol 98 (15) ◽

pp. e15014

Author(s):

Kévin Diallo ◽

Caroline Jacquet ◽

Corentine Alauzet ◽

Isabelle Beguinot ◽

Thierry May ◽

...

Keyword(s):

Case Report ◽

Infective Endocarditis ◽

Guillain Barre Syndrome ◽

Guillain Barré Syndrome ◽

Guillain Barré

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Co-Occurrence of Guillain-Barre Syndrome and Multiple Sclerosis: A Rare Case Report

Dubai Medical Journal ◽

10.1159/000512773 ◽

2021 ◽

pp. 1-5

Author(s):

Amr Hassan ◽

Alaa El-Mazny ◽

Mohammed Saher ◽

Ismail Ibrahim Ismail ◽

Mohammed Almuqbil

Keyword(s):

Multiple Sclerosis ◽

Differential Diagnosis ◽

Case Report ◽

Rare Case ◽

Guillain Barre Syndrome ◽

Guillain Barré Syndrome ◽

Rare Case Report ◽

Central Nervous Systems ◽

Guillain Barré ◽

Demyelinating Disorders

Guillain-Barre syndrome (GBS) and multiple sclerosis (MS) are autoimmune demyelinating disorders of the peripheral and central nervous systems, respectively. The co-occurrence of these 2 conditions is rare in the literature. Herein, we present a rare case of GBS and MS in a 19-year-old female who presented initially with GBS followed by MS, and we provide a literature review. Despite being rare, it should be kept in mind in the differential diagnosis of patients with atypical and usual presentation of both diseases.

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