Bilateral Panner’s disease in sickle cell anaemia: Case report

AbstractObjective:To present the first published case of a child with bilateral profound sudden sensorineural hearing loss found in association with sickle cell anaemia, and to demonstrate the importance of early recognition, investigation and empirical treatment of sudden sensorineural hearing loss.Method:Case report and review of world literature.Case report:The authors present the case of a seven-year-old child with known sickle cell anaemia, who presented with bilateral profound sensorineural hearing loss developing over a period of five days. There was a history of ophthalmological disease in the preceding weeks, and inflammatory markers were raised. The differential diagnosis included a vaso-occlusive or inflammatory aetiology such as Cogan's syndrome, and treatment for both was instigated. Hearing thresholds did not recover, and the patient underwent cochlear implantation 12 weeks later.Conclusion:Sudden sensorineural hearing loss has a variable aetiology and is rare in children. Immediate treatment for all possible aetiologies is essential, along with targeted investigations and early referral for cochlear implantation if no recovery is demonstrated.

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Sickle cell anaemia in vaso-occlusive crisis and acute fatty liver of pregnancy: a case report

Ghana Medical Journal ◽

10.4314/gmj.v54i3.12 ◽

2020 ◽

Vol 54 (3) ◽

pp. 201-203

Author(s):

Michael Ezeanochie ◽

Oghenefegor Olokor ◽

Ofure Yamah

Keyword(s):

Case Report ◽

Fatty Liver ◽

Sickle Cell ◽

Sickle Cell Anaemia ◽

Elevated Serum ◽

Simultaneous Occurrence ◽

Published Data ◽

Care Providers ◽

Delay In Diagnosis ◽

Acute Fatty Liver

Acute fatty liver of pregnancy (AFLP) is an uncommon condition that manifests in the third trimester of pregnancy.Its association with vaso-occlusive crisis from Sickle Cell Anaemia is not common. Published data on the simultaneous occurrence of these two conditions is rare, hence this case report. A 32-year-old gravida 3 para 1+1 lady, with Sickle Cell Anaemia, had a vaso-occlusive crisis in association with AFLP at 32 weeks’ gestation, and the outcome of her management was successful. AFLP is a rare late-gestational event affecting about 1 in 10,000 to 15,000 pregnancies. The exact aetiology is not known. Profound hypoglycaemia and jaundice with elevated serum transaminases are recognized features of AFLP.These features may also be seen in haemoglobinopathies. The simultaneous occurrence of AFLP and Sickle Cell Anaemia may result in overlap of symptoms and delay in diagnosis and treatment. Therefore, maintaining a high index of suspicion is key. The cornerstone for treatment remains prompt delivery and supportive care. AFLP can coexist with Sickle cell crises. It is important that care providers, especially in populations with high burden of Sickle Cell Anaemia, consider this as a differential diagnosis, especially when the jaundice is associated with profound or recurring episodes of hypoglycaemia. Prompt diagnosis and delivery in a multidisciplinary approach is important to avoid adverse maternal and foetal outcomes.Keywords: Vaso-occlusive crises, acute fatty liver of pregnancy, hypoglycaemia, Sickle-cell anaemiaFunding: No funding sources

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Dependence Syndrome in a Male Nigerian Adult with Sickle Cell Anaemia : A Case Report

Biosciences Biotechnology Research Asia ◽

10.13005/bbra/911 ◽

2011 ◽

Vol 8 (2) ◽

pp. 623-626

Author(s):

V.O. Awusi ◽

E.B. Lawani

Keyword(s):

Case Report ◽

Sickle Cell ◽

Sickle Cell Anaemia

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Polyuria and vaso-occlusive crises in sickle cell anaemia — A case report

European Journal of Internal Medicine ◽

10.1016/j.ejim.2013.08.449 ◽

2013 ◽

Vol 24 ◽

pp. e174

Author(s):

J. Jácome ◽

I. Terrahe ◽

C. Rodrigues ◽

V. Kryvonos ◽

P. Mendonça ◽

...

Keyword(s):

Case Report ◽

Sickle Cell ◽

Sickle Cell Anaemia

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Diabetic-ketoacidosis in a nine-year-old child with homozygous sickle cell anaemia: a rare case report

Pan African Medical Journal ◽

10.11604/pamj.2019.33.7.18971 ◽

2019 ◽

Vol 33 ◽

Author(s):

Nuraddeen Ibrahim ◽

Abubakar Sani Lugga ◽

Olayinka Rasheed Ibrahim

Keyword(s):

Case Report ◽

Diabetic Ketoacidosis ◽

Sickle Cell ◽

Rare Case ◽

Sickle Cell Anaemia ◽

Rare Case Report

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Case Report of a Giant Adrenal Myelolipoma in a Patient with Sickle Cell Anaemia

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2021/v33i1731032 ◽

2021 ◽

pp. 88-93

Author(s):

Udochikwuka Patience Ikejiaku ◽

Chidinma Adaobi Udah ◽

Johnpatrick Uchenna Ugwoegbu ◽

Emeka Nwolisa

Keyword(s):

Case Report ◽

Physical Examination ◽

Sickle Cell ◽

Sickle Cell Anaemia ◽

Imaging Techniques ◽

Vena Cava ◽

Operative Management ◽

Lumbar Region ◽

Adrenal Myelolipoma ◽

The Right

Adrenal myelolipomas (AMLs) are rare benign adrenal tumours containing adipose and hematopoietic tissue as a result of reticuloendothelial cell metaplasia. In this case report, we describe the diagnostic evaluation and the operative management of a giant adrenal myelolipoma in a 14-year-old male who has sickle cell anaemia. He presented with a one-week history of bilateral leg swelling. A physical examination revealed a mass in the right lumbar region. Ultrasound of the abdomen revealed a well-defined rounded echo-complex encapsulated supra-renal mass impinging on the upper pole of the right kidney, displacing it downwards. There was also marked compression of the inferior vena cava. A computed tomography scan showed a large mass occupying the right adrenal gland. The patient had an exploratory laparotomy with excision of the right adrenal tumour. Histopathological (Immunohistochemistry) evaluation of the mass confirmed the diagnosis of adrenal myelolipoma. The diagnosis of an adrenal myelolipoma requires a good history, physical examination, a high index of suspicion, imaging techniques, and a thorough histopathological evaluation. Surgery is the main treatment modality and good post-operative management minimizes complications and guarantees rapid recovery.

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