scholarly journals Bacterial adhesion to Conventional and Silicone hydrogel contact lenses

2021 ◽  
Vol 23 (1) ◽  
pp. 25-35
Author(s):  
Eghosasere Iyamu ◽  
Frederick Osaro Ekhaise
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Contact Lens ◽  
Bacterial Adhesion ◽  
Contact Lenses ◽  
Bacterial Species ◽  
Soft Contact ◽  
Silicone Hydrogel ◽  
Soft Contact Lenses ◽  
Lens Wear

Purpose: The aim of this study was to investigate the adhesion of bacteria to worn silicone hydrogel and conventional soft contact lenses.Methods: Bacterial adhesion experiments / assays were performed on 24 worn and 6 unworn soft contact lenses each of different materials (high- and low- gas permeable lenses) using the strains such as Pseudomonas aeruginosa ATCC 27853 and Staphylococcus aureus ATCC 25923.Results: P. aeruginosa adhered in increased number to worn than unworn Lotrafilcon A and conventional lenses. However, a higher number of P. aeruginosa adhered to unworn than worn Lotrafilcon B, the difference in the mean adhesion was not significant (p = 0.66). S. aureus adhered in significantly decreased number to worn Lotrafilcon A, nelfilcon A, nesofilcon A, etafilcon A and omafilcon A (p<0.05); butsignificantly higher number adhered to worn than unworn polymacon (p<0.05). Lens wear had no effect on the adhesion of S. aureus to Lotrafilcon B (p>0.05). The least adhesion of P. aeruginosa to worn contact lenses was seen with polymacon, while S. aureus adhered in least number to worn Lotrafilcon A compared to the other contact lens materials that demonstrated the same trend in adhesion.Conclusion: The higher adhesion of P. aeruginosa to worn lenses is consistent with the claim that it is the most implicated in all culture-positive contact lens related bacterial keratitis. Lens wear has different effects on bacterial adhesion, which may be due to type of lens materials and bacterial species/genera studied. Keywords: Silicone hydrogel lenses, conventional lenses, Pseudomonas aeruginosa, Staphylococcus aureus, bacterial adhesion.

scholarly journals Comparison of the Antimicrobial Efficacy of Various Contact Lens Solutions to Inhibit the Growth of Pseudomonas aeruginosa and Staphylococcus aureus

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
B. Laxmi Narayana ◽  
Pooja Rao ◽  
Sevitha Bhat ◽  
K. Vidyalakshmi
Keyword(s):  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Contact Lens ◽  
Contact Lenses ◽  
Bacterial Species ◽  
Antimicrobial Effect ◽  
Test Method ◽  
Medical College ◽  
Soft Contact Lenses ◽  
Contact Lens Solution

Soft contact lenses provide perfect conditions for the breeding of pathogens. The study is a prospective, experimental study, conducted to know the antimicrobial ability of multipurpose contact lens solution against standard strains of Staphylococcus aureus and Pseudomonas aeruginosa by the stand-alone test. The test method is based on the procedures in the ISO 14729 standard primary stand-alone test. Three multipurpose contact lens care solutions commercially available in Mangalore markets, namely, Biotrue (Bausch & Lomb), Opti-Free Replenish (Alcon), and Aquasoft (Stericon Pharma), were tested for its antimicrobial effect in the microbiology lab at Kasturba Medical College, Mangalore. According to this study, the solutions named “Biotrue” and “Aquasoft” met the primary stand-alone and reached the 3log reduction and 5log reduction criteria in the manufacturer recommended time, respectively. No conclusion could be drawn for Opti-Free Replenish since the minimum recommended disinfection time was overnight, whereas it was noted for 6 hr only, and it should have been experimented further. The effectiveness of multipurpose solutions varies against different bacterial species. We have observed that the antimicrobial activity of different solutions varies with respect to time of incubation, and also there was a marked difference in the activity of some solutions against S. aureus and P. aeruginosa. So, it is necessary for the contact lens users to store their lenses in solutions for longer duration of hours. It is also recommended to use solutions that clear the ISO 14729 standards for better health conditions of the eye.

scholarly journals The influence of water content and ionicity on the efficacy of soft contact lens care regimens on Pseudomonas aeruginosa

2021 ◽  
Vol 80 (1) ◽  
Author(s):  
Rekha Hansraj ◽  
Siddeeqa Jhetam ◽  
Jared Haridutt ◽  
Tymon Lahner ◽  
Sthabile Madlala ◽  
...  
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Water Content ◽  
Contact Lens ◽  
Contact Lenses ◽  
High Water ◽  
Health Science ◽  
High Water Content ◽  
Three Solutions ◽  
Soft Contact ◽  
Soft Contact Lenses

Background: Contact lens care regimens appear to be prescribed based on familiarity or by matching contact lens brands rather than consideration to efficacy.Aim: This study compared the effectiveness of multipurpose and peroxide cleaning solutions on low- and high-water content ionic and non-ionic soft contact lenses, in removing Pseudomonas aeruginosa (P. aeruginosa).Setting: The laboratory work was conducted by health science students in a graduate level programme in the microbiology laboratory at a university in south-eastern South Africa.Methods: A quantitative analytical experimental design was used. Four groups (labelled I, II, III and IV) of soft contact lenses, varied ionicity and water content were inoculated with P. aeruginosa and then exposed to three solutions containing antimicrobial ingredients, polyaminopropyl biguanide (Dymed), hydrogen peroxide (H2O2) and polyquaternium-1 (Polyquad). Each group contained 14 soft contact lenses, with the exception of Group III in which eight lenses were used. Saline served as the control. After 18 h, the remaining colony-forming units were counted using visual inspection as an indicator of efficacy against P. aeruginosa.Results: The solution containing H2O2 was found to be the most effective in removing P. aeruginosa from all Food and Drug Administration (FDA) groups of contact lenses whilst Dymed was found to be comparatively ineffective for this organism. Water content and ionicity had no effect on the efficacy of the solutions.Conclusion: Practitioners should consider the efficacy of the active ingredients against microorganisms when dispensing contact lens solutions, particularly for contact lens wearers at risk for P. aeruginosa infections.

scholarly journals Contact Lens Visual Rehabilitation in Keratoconus and Corneal Keratoplasty

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Yelda Ozkurt ◽  
Mehmet Atakan ◽  
Tugba Gencaga ◽  
Sezen Akkaya
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Soft Contact ◽  
Visual Rehabilitation ◽  
Adequate Treatment ◽  
Contact Lens Wear ◽  
Soft Contact Lenses ◽  
Thinning Process ◽  
Lens Wear ◽  
Spectacle Correction

Keratoconus is the most common corneal distrophy. It’s a noninflammatory progressive thinning process that leads to conical ectasia of the cornea, causing high myopia and astigmatism. Many treatment choices include spectacle correction and contact lens wear, collagen cross linking, intracorneal ring segments implantation and finally keratoplasty. Contact lenses are commonly used to reduce astigmatism and increase vision. There are various types of lenses are available. We reviewed soft contact lenses, rigid gas permeable contact lenses, piggyback contact lenses, hybrid contact lenses and scleral-semiscleral contact lenses in keratoconus management. The surgical option is keratoplasty, but even after sutur removal, high astigmatism may stil exists. Therefore, contact lens is an adequate treatment option to correct astigmatism after keratoplasty.

scholarly journals Characterization of Soft Contact Lens Edge Fitting during Daily Wear Using Ultrahigh-Resolution Optical Coherence Tomography

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Lele Cui ◽  
Sisi Chen ◽  
Weihe Zhou ◽  
Kaixuan Sheng ◽  
Lei Zhang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Contact Lens ◽  
Contact Lenses ◽  
Optical Coherence ◽  
Soft Contact ◽  
Ultrahigh Resolution ◽  
Soft Contact Lenses ◽  
Soft Contact Lens ◽  
Lens Wear ◽  
Peripheral Cornea

Purpose. To determine conjunctival overlap over the edge of soft contact lens and to visualize the peripheral postlens tear film (PoLTF) underneath soft contact lenses using ultrahigh-resolution optical coherence tomography (UHR-OCT). Methods. Twenty participants (4 males and 16 females, 23.0 ± 3.7 years) were fitted with two different types of soft contact lenses randomly. The limbus with lens was imaged with the UHR-OCT at the horizontal meridian every two hours up to 6 hours during lens wear. The conjunctival overlap was ranked as the percentage of the edge covered by the conjunctiva. The frequency of occurrence for visualized peripheral PoLTF was determined. Results. The average conjunctival overlaps at insertion were 49% and 73% for galyfilcon A and balafilcon A lenses and increased significantly to 84% and 90% by 6 hours of lens wear (P<0.001). Lenses with rounded edges had more conjunctival overlap than the lenses with angled edges (P=0.014). There were significant decreases for PoLTF on the conjunctiva (P=0.014) and peripheral cornea (P=0.004) over the study period compared to insertion. The percentage of subjects with PoLTF on the conjunctiva (32.5%) and peripheral cornea (36%) were greater in subjects wearing balafilcon A lenses (P=0.017). Conclusions. Increased conjunctival overlap over the lens edges and reduced PoLTF underneath the peripheral region of soft contact lenses were shown during lens daily wear. The lens edge configuration may play a role in conjunctival response and peripheral PoLTF.

scholarly journals The structure of soft contact lens users and the incidence of papillary conjunctivitis in the analyzed groups according to the data of “Krugozor” ophthalmology clinic

The Eye ◽  
2020 ◽  
Vol 22 (4(132)) ◽  
pp. 30-35
Author(s):  
O. V. Dubovtseva ◽  
N. A. Bakalova
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Moderate Degree ◽  
Soft Contact ◽  
Wear Time ◽  
Soft Contact Lenses ◽  
Soft Contact Lens ◽  
Vision Correction ◽  
Lens Wear ◽  
Giant Papillary Conjunctivitis

Introduction. Vision correction by contact lenses is one of the most common and effective methods for correcting refractive errors in children and adults. Compliance with rules of soft contact lenses (SCLs) wearing is one of the most important conditions for a safe use, while violation of compliance is usually the main cause of complications.Purpose. To study the structure of contact lens wearers by ametropia and lens wearing time as well as to determine the relationship between the incidence of giant papillary conjunctivitis (GPC) with lens wear time and overwear time.Material and methods. A retrospective analysis of 1 000 records (1 000 patients) of patients who underwent vision correction by SCLs in “Krugozor” ophthalmology clinic in the year 2019 was carried out. Mean age of patients was 24.95 ± 8.62 years. Age, type and degree of ametropia, material (hydrogel, silicone hydrogel or biocompatible hydrogel), lens replacement schedule, presence of complications, lens overwear time and daily wear time were taken into account.Results. Most SCLs users are patients between 21 and 30 years old (47%) who have a moderate degree of ametropia (52%). Most of them (46%) preferred monthly replacement SCLs, 29% – bi-weekly replacement SCLs, 9% preferred daily replacement lenses, while quarterly replacement lenses were used by 16%. Only 26.9% of SCL users complied with the instructions for lens wear, while for 29.4% of them lens overwear time amounted to up to 14 days, for 34.1% – up to 28 days, and for 9.6% – more than 1 month. More than half (56%) of patients mainly wore SCLs during 16 hours a day, one in five (22.7%) used SCLs during 12 hours a day, and 12.6% – up to 20 hours a day. 8.7% wore lenses during up to 7 days. The incidence of GPC in patients who did not comply with replacement schedule and were overwearing lenses was significantly higher (38.71%) than in patients who followed the replacement schedule (3.21%).Conclusion. More than half of the users comprised young people with a moderate degree of myopia. The most commonly used SCLs were monthly replacement. It was discovered that only one in four wearers followed recommendations of manufacturers and replaced lenses on time. Lens overwear may lead to a development of a giant papillary conjunctivitis (GPC). 

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